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Drug repositioning is an attractive cost-efficient strategy for the development of treatments for human diseases. Here, we propose an interpretable model that learns disease self-representations for drug repositioning. Our…

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…

Computation and Language · Computer Science 2018-08-09 Peter J. Liu

Effectively representing medical concepts and patients is important for healthcare analytical applications. Representing medical concepts for healthcare analytical tasks requires incorporating medical domain knowledge and prior information…

Machine Learning · Computer Science 2023-05-02 Shaodong Wang , Qing Li , Wenli Zhang

Algorithmic case-based decision support provides examples to help human make sense of predicted labels and aid human in decision-making tasks. Despite the promising performance of supervised learning, representations learned by supervised…

Machine Learning · Computer Science 2023-03-10 Han Liu , Yizhou Tian , Chacha Chen , Shi Feng , Yuxin Chen , Chenhao Tan

Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

Machine Learning · Computer Science 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Entity recognition is a critical first step to a number of clinical NLP applications, such as entity linking and relation extraction. We present the first attempt to apply state-of-the-art entity recognition approaches on a newly released…

Computation and Language · Computer Science 2019-10-04 Kathleen C. Fraser , Isar Nejadgholi , Berry De Bruijn , Muqun Li , Astha LaPlante , Khaldoun Zine El Abidine

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Genomics are rapidly transforming medical practice and basic biomedical research, providing insights into disease mechanisms and improving therapeutic strategies, particularly in cancer. The ability to predict the future course of a…

Neural and Evolutionary Computing · Computer Science 2016-09-29 Safoora Yousefi , Congzheng Song , Nelson Nauata , Lee Cooper

Today, machine learning is applied in almost any field. In machine learning, where there are numerous methods, classification is one of the most basic and crucial ones. Various problems can be solved by classification. The feature selection…

Machine Learning · Computer Science 2022-07-01 Ahmet Tuğrul Bayrak

Electronic health record (EHR) foundation models have been an area ripe for exploration with their improved performance in various medical tasks. Despite the rapid advances, there exists a fundamental limitation: Processing unseen medical…

Artificial Intelligence · Computer Science 2025-08-15 Junmo Kim , Namkyeong Lee , Jiwon Kim , Kwangsoo Kim

The success of neural networks builds to a large extent on their ability to create internal knowledge representations from real-world high-dimensional data, such as images, sound, or text. Approaches to extract and present these…

Artificial Intelligence · Computer Science 2023-01-03 Lars Holmberg , Paul Davidsson , Per Linde

Electronic health records (EHRs), digital collections of patient healthcare events and observations, are ubiquitous in medicine and critical to healthcare delivery, operations, and research. Despite this central role, EHRs are notoriously…

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-10-01 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

Collaborative filtering (CF) is a core technique for recommender systems. Traditional CF approaches exploit user-item relations (e.g., clicks, likes, and views) only and hence they suffer from the data sparsity issue. Items are usually…

Information Retrieval · Computer Science 2020-10-19 Guangneng Hu

A key component of deep learning (DL) for natural language processing (NLP) is word embeddings. Word embeddings that effectively capture the meaning and context of the word that they represent can significantly improve the performance of…

Automated analysis of chest radiography using deep learning has tremendous potential to enhance the clinical diagnosis of diseases in patients. However, deep learning models typically require large amounts of annotated data to achieve high…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Keegan Quigley , Miriam Cha , Ruizhi Liao , Geeticka Chauhan , Steven Horng , Seth Berkowitz , Polina Golland

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-09-23 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

Finetuning is a common practice widespread across different communities to adapt pretrained models to particular tasks. Text classification is one of these tasks for which many pretrained models are available. On the other hand, ensembles…

Computation and Language · Computer Science 2024-10-29 Sebastian Pineda Arango , Maciej Janowski , Lennart Purucker , Arber Zela , Frank Hutter , Josif Grabocka

In this paper, we describe TextEnt, a neural network model that learns distributed representations of entities and documents directly from a knowledge base (KB). Given a document in a KB consisting of words and entity annotations, we train…

Computation and Language · Computer Science 2018-06-11 Ikuya Yamada , Hiroyuki Shindo , Yoshiyasu Takefuji

Data representation is a fundamental task in machine learning. The representation of data affects the performance of the whole machine learning system. In a long history, the representation of data is done by feature engineering, and…

Computation and Language · Computer Science 2016-11-21 Siwei Lai
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