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Incorporating historical or real-world data into analyses of treatment effects for rare diseases has become increasingly popular. A major challenge, however, lies in determining the appropriate degree of congruence between historical and…

Methodology · Statistics 2025-10-01 Shixuan Wang , Jing Zhang , Emily L. Kang , Bin Zhang

Most scientific publications follow the familiar recipe of (i) obtain data, (ii) fit a model, and (iii) comment on the scientific relevance of the effects of particular covariates in that model. This approach, however, ignores the fact that…

Methodology · Statistics 2021-03-08 Nicholas Kissel , Lucas Mentch

Using the perturbation-response scanning (PRS) technique, we study a set of 23 proteins that display a variety of conformational motions upon ligand binding (e.g. shear, hinge, allosteric). In most cases, PRS determines residues that may be…

Biomolecules · Quantitative Biology 2015-05-18 C Atilgan , Z N Gerek , S B Ozkan , A R Atilgan

The conventional formulation of quantum sensing is based on the assumption that the probe is reset to its initial state after each measurement. In a very distinct approach, one can also pursue a sequential measurement scheme in which…

Quantum Physics · Physics 2023-08-08 Yaoling Yang , Victor Montenegro , Abolfazl Bayat

Mixed membership models are an extension of finite mixture models, where each observation can partially belong to more than one mixture component. A probabilistic framework for mixed membership models of high-dimensional continuous data is…

Receiver sensitivity is a particularly important metric in optical communication links operating at low signal-to-noise ratios (SNRs), for example in deep-space communication, since it directly limits the maximum achievable reach and data…

Signal Processing · Electrical Eng. & Systems 2021-04-23 Ravikiran Kakarla , Mikael Mazur , Jochen Schröder , Peter A. Andrekson

We study the fundamental bounds on precision measurements of parameters contained in a time-dependent nonlinear optomechanical Hamiltonian, which includes the nonlinear light-matter coupling, a mechanical displacement term, and a…

A suitable scalar metric can help measure multi-calibration, defined as follows. When the expected values of observed responses are equal to corresponding predicted probabilities, the probabilistic predictions are known as "perfectly…

Methodology · Statistics 2026-04-17 Ido Guy , Daniel Haimovich , Fridolin Linder , Nastaran Okati , Lorenzo Perini , Niek Tax , Mark Tygert

This paper proposes a verification-based decoding approach for reconstruction of a sparse signal with incremental sparse measurements. In its first step, the verification-based decoding algorithm is employed to reconstruct the signal with a…

Information Theory · Computer Science 2013-02-12 Xiaofu Wu , Zhen Yang , Lu Gan

We investigate the sequential composition of weak values in the framework of time-symmetric quantum mechanics. Specifically, we consider a forward'' weak measurement from a preselected state $\ket{\psi}$ to a post-selected state…

Quantum Physics · Physics 2025-07-15 Mirco A. Mannucci

The accuracy of a measurement of the spin direction of a spin-s particle is characterised, for arbitrary half-integral s. The disturbance caused by the measurement is also characterised. The approach is based on that taken in several…

Quantum Physics · Physics 2007-05-23 D. M. Appleby

The weak measurements based amplification of ultra-small phase was proposed in our previous work. Due to the technical imperfections, the ability of amplification is usually limited in practice. Here we introduce the concept of cascaded…

Quantum Physics · Physics 2017-09-06 Meng-Jun Hu , Yong-Sheng Zhang

Modulation constellation design is a core challenge in digital communications, especially under stringent demands on spectral efficiency, robustness, and energy consumption. Classical schemes like PSK and QAM, while analytically tractable,…

Signal Processing · Electrical Eng. & Systems 2026-01-22 Nipun Agarwal

This paper studies the optimal transmission switching (OTS) problem for power systems, where certain lines are fixed (uncontrollable) and the remaining ones are controllable via on/off switches. The goal is to identify a topology of the…

Optimization and Control · Mathematics 2017-11-29 Salar Fattahi , Javad Lavaei , Alper Atamturk

It is known that protocols based on weak measurements can be used to steer quantum systems into pre-designated pure states. Here we show that weak-measurement-based steering protocols can be harnessed for on-demand engineering of…

Quantum Physics · Physics 2020-10-28 Parveen Kumar , Kyrylo Snizhko , Yuval Gefen

Compressive sensing has been receiving a great deal of interest from researchers in many areas because of its ability in speeding up data acquisition. This framework allows fast signal acquisition and compression when signals are sparse in…

Information Theory · Computer Science 2020-03-17 Fatima Salahdine , Elias Ghribi , Naima Kaabouch

In this paper, we compare four measures of the empirical observability gramian, including the determinant, the trace, the minimum eigenvalue, and the condition number, which can be used to quantify the observability of system states and to…

Optimization and Control · Mathematics 2016-06-09 Junjian Qi , Kai Sun , Wei Kang

A calibration scheme is presented for improved polarization state measurement of terahertz pulses. In this scheme the polarization response of a two-contact terahertz photoconductive detector is accurately measured, and is used to correct…

Optics · Physics 2012-01-25 M. Neshat , N. P. Armitage

We introduce a new approach to variable selection, called Predictive Correlation Screening, for predictor design. Predictive Correlation Screening (PCS) implements false positive control on the selected variables, is well suited to small…

Machine Learning · Statistics 2013-04-11 Hamed Firouzi , Bala Rajaratnam , Alfred Hero

Genetic algorithms are a widely used method in chemometrics for extracting variable subsets with high prediction power. Most fitness measures used by these genetic algorithms are based on the ordinary least-squares fit of the resulting…

Computation · Statistics 2017-11-21 David Kepplinger , Peter Filzmoser , Kurt Varmuza