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We consider a stochastic SIS infection model for a population partitioned into $m$ households assuming random mixing. We solve the model in the limit $m \to \infty$ by using the self-consistent field method of statistical physics. We derive…

Statistical Mechanics · Physics 2007-05-23 G. Ghoshal , L. M. Sander , I. M. Sokolov

We show that disease transmission models in a spatially heterogeneous environment can have a large number of coexisting endemic equilibria. A general compartmental model is considered to describe the spread of an infectious disease in a…

Classical Analysis and ODEs · Mathematics 2014-04-01 Diána H. Knipl , Gergely Röst

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

Applications · Statistics 2014-11-18 Le Bao , Mary Mahy , Xiaoyue Niu , Tim Brown , Peter Ghys

The impact of spatial structure on the spread of an epidemic is an important issue in the propagation of infectious diseases. Recent studies, both deterministic and stochastic, have made it possible to understand the importance of the…

Probability · Mathematics 2023-01-09 Alphonse Emakoua

In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape from multiple CTL responses. Under this model, we describe two…

Populations and Evolution · Quantitative Biology 2012-08-16 Sivan Leviyang

The worldwide spread of COVID-19 has called for fast advancement of new modelling strategies to estimate its unprecedented spread. Here, we introduce a model based on the fundamental SIR equations with a stochastic disorder by a random…

Physics and Society · Physics 2020-04-28 Suman Dutta

The study of epidemic models plays an important role in mathematical epidemiology. There are many researches on epidemic models using ordinary differential equations, partial differential equations or stochastic differential equations. In…

Probability · Mathematics 2023-03-10 Yuqi Li , Lihua Zhang

In this paper, we investigate a novel 3-compartment model of HIV infection of CD4$^+$ T-cells with a mass action term by including two versions: one baseline ODE model and one delay-differential equation (DDE) model with a constant discrete…

Populations and Evolution · Quantitative Biology 2021-01-05 Hoang Anh Ngo , Hung Dang Nguyen , Mehmet Dik

The precise mechanism that causes HIV infection to progress to AIDS is still unknown. This paper presents a mathematical model which is able to predict the entire trajectory of the HIV/AIDS dynamics, then a possible explanation for this…

Cell Behavior · Quantitative Biology 2015-03-19 Esteban A. Hernandez-Vargas , Dhagash Mehta , Richard H. Middleton

This article is concerned with a nonlocal dispersal susceptible-infected-susceptible (SIS) epidemic model with Neumann boundary condition, where the rates of disease transmission and recovery are assumed to be spatially heterogeneous and…

Analysis of PDEs · Mathematics 2016-01-21 Fei-Ying Yang , Wan-Tong Li , Liang Zhang

We have developed a mathematical model for in-host virus dynamics that includes spatial chemotaxis and diffusion across a two dimensional surface representing the vaginal or rectal epithelium at primary HIV infection. A linear stability…

Quantitative Methods · Quantitative Biology 2016-03-07 Ognjen Stancevic , Christopher Angstmann , John M. Murray , Bruce I. Henry

In this paper, we further investigate the global dynamics of a stochastic differential equation SIS (Susceptible-Infected-Susceptible) epidemic model recently proposed in [A. Gray et al., SIAM. J. Appl. Math., 71 (2011), 876-902]. We…

Dynamical Systems · Mathematics 2016-08-24 Chuang Xu

We use a cellular automata model to study the evolution of HIV infection and the onset of AIDS. The model takes into account the global features of the immune response to any pathogen, the fast mutation rate of the HIV and a fair amount of…

Statistical Mechanics · Physics 2009-10-31 Rita Maria Zorzenon dos Santos , Sergio Coutinho

A stochastic SIR epidemic model taking into account the heterogeneity of the spatial environment is constructed. The deterministic model is given by a partial differential equation and the stochastic one by a space-time jump Markov process.…

Probability · Mathematics 2024-12-10 Thierry Gallouët , Etienne Pardoux , Ténan Yeo

This work proposes and analyzes a family of spatially inhomogeneous epidemic models. This is our first effort to use stochastic partial differential equations (SPDEs) to model epidemic dynamics with spatial variations and environmental…

Dynamical Systems · Mathematics 2020-01-01 Dang H Nguyen , Nhu N Nguyen , George Yin

In this article, we construct a numerical method for a stochastic version of the Susceptible Infected Susceptible (SIS) epidemic model, expressed by a suitable stochastic differential equation (SDE), by using the semi-discrete method to a…

Numerical Analysis · Mathematics 2023-07-28 Yiannis Kiouvrekis , Ioannis S. Stamatiou

This paper considers a mathematical model based on the transmission dynamics of hepatitis C virus (HCV) infection. In addition to the usual compartments for susceptible, exposed, and infected individuals, this model includes compartments…

Populations and Evolution · Quantitative Biology 2017-12-25 Daniah Tahir , Abid Ali Lashari , Kazeem Oare Okosun

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

Dynamical Systems · Mathematics 2025-10-03 Abdallah Alsammani

We study the spread of disease in an SIS model. The model considered is a time-varying, switched model, in which the parameters of the SIS model are subject to abrupt change. We show that the joint spectral radius can be used as a threshold…

Dynamical Systems · Mathematics 2014-04-21 Mustapha Ait Rami , Vahid S. Bokharaie , Oliver Mason , Fabian R. Wirth