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Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu

Deep learning has emerged as a promising approach for learning the nonlinear mapping between diffusion-weighted MR images and tissue parameters, which enables automatic and deep understanding of the brain microstructures. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenxin Fan , Jian Cheng , Qiyuan Tian , Ruoyou Wu , Juan Zou , Zan Chen , Shanshan Wang

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Recent studies show that deep learning (DL) based MRI reconstruction outperforms conventional methods, such as parallel imaging and compressed sensing (CS), in multiple applications. Unlike CS that is typically implemented with…

Image and Video Processing · Electrical Eng. & Systems 2022-08-22 Hongyi Gu , Burhaneddin Yaman , Steen Moeller , Il Yong Chun , Mehmet Akçakaya

Deep learning (DL) has emerged as a leading approach in accelerating MR imaging. It employs deep neural networks to extract knowledge from available datasets and then applies the trained networks to reconstruct accurate images from limited…

Image and Video Processing · Electrical Eng. & Systems 2024-02-06 Shanshan Wang , Ruoyou Wu , Sen Jia , Alou Diakite , Cheng Li , Qiegen Liu , Leslie Ying

A novel unsupervised deep learning method is developed to identify individual-specific large scale brain functional networks (FNs) from resting-state fMRI (rsfMRI) in an end-to-end learning fashion. Our method leverages deep Encoder-Decoder…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Hongming Li , Yong Fan

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data. Here we show that a single self-supervised representation can…

Machine Learning · Computer Science 2026-05-27 Yizhou Wu , Shansong Wang , Yuheng Li , Mojtaba Safari , Mingzhe Hu , Chih-Wei Chang , Harini Veeraraghavan , Xiaofeng Yang

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

While functional Magnetic Resonance Imaging (fMRI) offers valuable insights into cognitive processes, its inherent spatial limitations pose challenges for detailed analysis of the fine-grained functional architecture of the brain. More…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Fernando Pérez-Bueno , Hongwei Bran Li , Matthew S. Rosen , Shahin Nasr , Cesar Caballero-Gaudes , Juan Eugenio Iglesias

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Deep Learning (DL) methods can reconstruct highly accelerated magnetic resonance imaging (MRI) scans, but they rely on application-specific large training datasets and often generalize poorly to out-of-distribution data. Self-supervised…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Hongze Yu , Jeffrey A. Fessler , Yun Jiang

Although deep learning has solved difficult problems in visual pattern recognition, it is mostly successful in tasks where there are lots of labeled training data available. Furthermore, the global back-propagation based training rule and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-03 Luis Sa-Couto , Andreas Wichert

Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Fang-Cheng Yeh

Unsupervised learning has always been appealing to machine learning researchers and practitioners, allowing them to avoid an expensive and complicated process of labeling the data. However, unsupervised learning of complex data is…

Computer Vision and Pattern Recognition · Computer Science 2020-11-10 Evgenii Zheltonozhskii , Chaim Baskin , Alex M. Bronstein , Avi Mendelson

Deep learning (DL) based unrolled reconstructions have shown state-of-the-art performance for under-sampled magnetic resonance imaging (MRI). Similar to compressed sensing, DL can leverage high-dimensional data (e.g. 3D, 2D+time, 3D+time)…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Ke Wang , Michael Kellman , Christopher M. Sandino , Kevin Zhang , Shreyas S. Vasanawala , Jonathan I. Tamir , Stella X. Yu , Michael Lustig

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

Image reconstruction from undersampled k-space data has been playing an important role for fast MRI. Recently, deep learning has demonstrated tremendous success in various fields and also shown potential to significantly speed up MR…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Dong Liang , Jing Cheng , Ziwen Ke , Leslie Ying