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Purpose. Early squamous cell neoplasia (ESCN) in the oesophagus is a highly treatable condition. Lesions confined to the mucosal layer can be curatively treated endoscopically. We build a computer-assisted detection (CADe) system that can…

Squamous Cell Carcinoma (SCC) is the most common cancer type of the epithelium and is often detected at a late stage. Besides invasive diagnosis of SCC by means of biopsy and histo-pathologic assessment, Confocal Laser Endomicroscopy (CLE)…

Computer Vision and Pattern Recognition · Computer Science 2020-01-06 Marc Aubreville , Miguel Goncalves , Christian Knipfer , Nicolai Oetter , Helmut Neumann , Florian Stelzle , Christopher Bohr , Andreas Maier

Convolutional neural networks have been shown to develop internal representations, which correspond closely to semantically meaningful objects and parts, although trained solely on class labels. Class Activation Mapping (CAM) is a recent…

Computer Vision and Pattern Recognition · Computer Science 2016-05-26 Amir Rosenfeld , Shimon Ullman

Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer of the oral epithelium. Despite their high impact on mortality, sufficient screening methods for early diagnosis of OSCC often lack accuracy and thus OSCCs are mostly diagnosed…

Computer Vision and Pattern Recognition · Computer Science 2017-09-21 Marc Aubreville , Christian Knipfer , Nicolai Oetter , Christian Jaremenko , Erik Rodner , Joachim Denzler , Christopher Bohr , Helmut Neumann , Florian Stelzle , Andreas Maier

Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hanliang Jiang , Fuhao Shen , Fei Gao , Weidong Han

Interpretation of deep learning remains a very challenging problem. Although the Class Activation Map (CAM) is widely used to interpret deep model predictions by highlighting object location, it fails to provide insight into the salient…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Yuguang Yang , Runtang Guo , Sheng Wu , Yimi Wang , Juan Zhang , Xuan Gong , Baochang Zhang

Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Oral squamous cell carcinoma (OSCC) represents a significant global health concern, with increasing incidence rates and challenges in early diagnosis and treatment planning. Early detection is crucial for improving patient outcomes and…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Samrat Kumar Dev Sharma

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

We present a reproducible deep learning pipeline for leukemic cell classification, focusing on system architecture, experimental robustness, and software design choices for medical image analysis. Acute lymphoblastic leukemia (ALL) is the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Douglas Costa Braga , Daniel Oliveira Dantas

Early detection of lung cancer is critical to improving survival outcomes. We present a deep learning framework for automated lung cancer screening from chest computed tomography (CT) images with integrated explainability. Using the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Nishan Rai , Sujan Khatri , Devendra Risal

With the growing demand for interpretable deep learning models, this paper introduces Integrative CAM, an advanced Class Activation Mapping (CAM) technique aimed at providing a holistic view of feature importance across Convolutional Neural…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Aniket K. Singh , Debasis Chaudhuri , Manish P. Singh , Samiran Chattopadhyay

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

The interpretability of deep neural networks has become a subject of great interest within the medical and healthcare domain. This attention stems from concerns regarding transparency, legal and ethical considerations, and the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Mahbub Ul Alam , Jaakko Hollmén , Jón Rúnar Baldvinsson , Rahim Rahmani

Oral Cavity Squamous Cell Carcinoma (OCSCC) is the most common type of head and neck cancer. Due to the subtle nature of its early stages, deep and hidden areas of development, and slow growth, OCSCC often goes undetected, leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Vishal Manikanden , Aniketh Bandlamudi , Daniel Haehn

Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Gyanendar Manohar , Ruairi O'Reilly

Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Mukaffi Bin Moin , Fatema Tuj Johora Faria , Swarnajit Saha , Busra Kamal Rafa , Mohammad Shafiul Alam

The convolutional neural network (CNN) has become a powerful tool for various biomedical image analysis tasks, but there is a lack of visual explanation for the machinery of CNNs. In this paper, we present a novel algorithm,…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Guannan Zhao , Bo Zhou , Kaiwen Wang , Rui Jiang , Min Xu

Screening is critical for prevention and early detection of cervical cancer but it is time-consuming and laborious. Supervised deep convolutional neural networks have been developed to automate pap smear screening and the results are…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Yu Ando , Nora Jee-Young Park and , Gun Oh Chong , Seokhwan Ko , Donghyeon Lee , Junghwan Cho , Hyungsoo Han
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