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Deep learning has been successfully applied to low-dose CT (LDCT) image denoising for reducing potential radiation risk. However, the widely reported supervised LDCT denoising networks require a training set of paired images, which is…

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second…

Computed Tomography (CT) plays a pivotal role in medical diagnosis; however, variability across reconstruction kernels hinders data-driven approaches, such as deep learning models, from achieving reliable and generalized performance. To…

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

In this paper, we introduced a novel deep learning-based reconstruction technique for low-dose CT imaging using 3 dimensional convolutions to include the sagittal information unlike the existing 2 dimensional networks which exploits…

Diversity in data is critical for the successful training of deep learning models. Leveraged by a recurrent generative adversarial network, we propose the CT-SGAN model that generates large-scale 3D synthetic CT-scan volumes ($\geq…

Cone Beam Computed Tomography(CBCT) is a now known method to conduct CT imaging. Especially, The Low Dose CT imaging is one of possible options to protect organs of patients when conducting CT imaging. Therefore Low Dose CT imaging can be…

Low-dose computed tomography (LDCT) has become the technology of choice for diagnostic medical imaging, given its lower radiation dose compared to standard CT, despite increasing image noise and potentially affecting diagnostic accuracy. To…

To facilitate a prospective estimation of CT effective dose and risk minimization process, a prospective spatial dose estimation and the known anatomical structures are expected. To this end, a CT reconstruction method is required to…

Recently, multi-channel speech enhancement has drawn much interest due to the use of spatial information to distinguish target speech from interfering signal. To make full use of spatial information and neural network based masking…

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion…

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Accurate Computer-Assisted Diagnosis, relying on large-scale annotated pathological images, can alleviate the risk of overlooking the diagnosis. Unfortunately, in medical imaging, most available datasets are small/fragmented. To tackle…

Low-dose computed tomography (LDCT) scans, which can effectively alleviate the radiation problem, will degrade the imaging quality. In this paper, we propose a novel LDCT reconstruction network that unrolls the iterative scheme and performs…

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…

In clinical examinations and diagnoses, low-dose computed tomography (LDCT) is crucial for minimizing health risks compared with normal-dose computed tomography (NDCT). However, reducing the radiation dose compromises the signal-to-noise…

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Complete and high-quality multi-modal Magnetic Resonance Imaging (MRI) is essential for accurate neuro-oncological assessment, as each contrast provides complementary anatomical and pathological information. However, acquiring all…