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With the advent of large language models (LLMs), there is a growing interest in applying LLMs to scientific tasks. In this work, we conduct an experimental study to explore applicability of LLMs for configuring, annotating, translating,…

Human-Computer Interaction · Computer Science 2025-10-13 Orcun Yildiz , Tom Peterka

Evolution Strategies are inspired in biology and part of a larger research field known as Evolutionary Algorithms. Those strategies perform a random search in the space of admissible functions, aiming to optimize some given objective…

Optimization and Control · Mathematics 2007-12-30 Pedro A. F. Cruz , Delfim F. M. Torres

Modern Large Language Model (LLM) serving operates in highly volatile environments characterized by severe runtime dynamics, such as workload fluctuations and elastic cluster autoscaling. Traditional serving systems rely on static,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-09 Youhe Jiang , Ran Yan , You Peng , Wenshuang Li , Taiyi Wang , Fangcheng Fu , Binhang Yuan

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

Context: Refactoring is the art of modifying the design of a system without altering its behavior. The idea is to reorganize variables, classes and methods to facilitate their future adaptations and comprehension. As the concept of behavior…

Software Engineering · Computer Science 2021-07-23 Eman Abdullah AlOmar , Mohamed Wiem Mkaouer , Christian Newman , Ali Ouni

The code written by developers usually suffers from efficiency problems and contain various performance bugs. These inefficiencies necessitate the research of automated refactoring methods for code optimization. Early research in code…

Software Engineering · Computer Science 2024-08-23 Shuzheng Gao , Cuiyun Gao , Wenchao Gu , Michael Lyu

Many tools used to process programs, like compilers, analyzers, or verifiers, perform transformations on their intermediate program representation, like abstract syntax trees. Implementing such program transformations is a non-trivial task,…

Programming Languages · Computer Science 2026-01-21 Michael Hanus , Steven Libby

Algorithms play a crucial role in many technological systems that control or affect various aspects of our lives. As a result, providing explanations for their decisions to address the needs of users and organisations is increasingly…

Software Engineering · Computer Science 2023-05-29 Trung Dong Huynh , Niko Tsakalakis , Ayah Helal , Sophie Stalla-Bourdillon , Luc Moreau

LLMs are widely used for code generation and mathematical reasoning tasks where they are required to generate structured output. They either need to reason about code, generate code for a given specification, or reason using programs of…

Computation and Language · Computer Science 2026-04-21 Poorva Garg , Renato Lui Geh , Daniel Israel , Todd Millstein , Kyle Richardson , Guy Van den Broeck

We propose a reinforcement-learning algorithm to tackle the challenge of reconstructing phylogenetic trees. The search for the tree that best describes the data is algorithmically challenging, thus all current algorithms for phylogeny…

Populations and Evolution · Quantitative Biology 2023-03-14 Dana Azouri , Oz Granit , Michael Alburquerque , Yishay Mansour , Tal Pupko , Itay Mayrose

One of the important questions in biological evolution is to know if certain changes along protein coding genes have contributed to the adaptation of species. This problem is known to be biologically complex and computationally very…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-03-15 Sébastien Moretti , Riccardo Murri , Sergio Maffioletti , Arnold Kuzniar , Briséïs Castella , Nicolas Salamin , Marc Robinson-Rechavi , Heinz Stockinger

Automating the end-to-end scientific research process poses a fundamental challenge: it requires both evolving high-level plans that are novel and sound, and executing these plans correctly amidst dynamic and uncertain conditions. To…

Artificial Intelligence · Computer Science 2025-10-09 Zhi Zhang , Yan Liu , Zhejing Hu , Gong Chen , Sheng-hua Zhong , Jiannong Cao

Plasticity-led evolution is a form of evolution where a change in the environment induces novel traits via phenotypic plasticity, after which the novel traits are genetically accommodated over generations under the novel environment. This…

Populations and Evolution · Quantitative Biology 2023-01-18 Eden Tian Hwa Ng , Akira R. Kinjo

In this paper, we develop approximate dynamic programming methods for stochastic systems modeled as Markov Decision Processes, given both soft performance criteria and hard constraints in a class of probabilistic temporal logic called…

Optimization and Control · Mathematics 2018-10-08 Lening Li , Jie Fu

Contemporary bioinformatics has seen in profound new visibility into the composition, structure, and history of the natural world around us. Arguably, the central pillar of bioinformatics is phylogenetics -- the study of hereditary…

Populations and Evolution · Quantitative Biology 2024-09-24 Matthew Andres Moreno , Mark T. Holder , Jeet Sukumaran

Real-time log analysis is the cornerstone of observability for modern infrastructure. However, existing online parsers are architecturally unsuited for the dynamism of production environments. Built on fundamentally static template models,…

Databases · Computer Science 2026-01-05 Satyam Singh , Sai Niranjan Ramachandran

Over the past decade, advances in generative modeling, such as generative adversarial networks, masked autoencoders, and diffusion models, have significantly transformed biological research and discovery, enabling breakthroughs in molecule…

Machine Learning · Computer Science 2026-03-10 Zihao Li , Zhichen Zeng , Xiao Lin , Feihao Fang , Yanru Qu , Zhe Xu , Zhining Liu , Xuying Ning , Tianxin Wei , Ge Liu , Hanghang Tong , Jingrui He

Recursive loops in a logic program present a challenging problem to the PLP framework. On the one hand, they loop forever so that the PLP backward-chaining inferences would never stop. On the other hand, they generate cyclic influences,…

Artificial Intelligence · Computer Science 2007-05-23 Y. D. Shen , Q. Yang , J. H. You , L. Y. Yuan

Evolutionary computation (EC), as a powerful optimization algorithm, has been applied across various domains. However, as the complexity of problems increases, the limitations of EC have become more apparent. The advent of large language…

Neural and Evolutionary Computing · Computer Science 2024-05-24 Jinyu Cai , Jinglue Xu , Jialong Li , Takuto Ymauchi , Hitoshi Iba , Kenji Tei