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Related papers: FPGA Acceleration of Short Read Alignment

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Genetic algorithms have played an important role in engineering optimization. Traditional GAs treat each gene separately. However, biophysical studies of gene regulatory networks revealed direct associations between different genes. It…

Neural and Evolutionary Computing · Computer Science 2024-05-01 Zhaoning Shi , Meng Xiang , Zhaoyang Hai , Xiabi Liu , Yan Pei

At the last step of short read mapping, the candidate locations of the reads on the reference genome are verified to compute their differences from the corresponding reference segments using sequence alignment algorithms. Calculating the…

Genomics · Quantitative Biology 2024-07-04 Zülal Bingöl , Mohammed Alser , Onur Mutlu , Ozcan Ozturk , Can Alkan

Field-Programmable Gate Array (FPGA)-based Software-Defined Radio (SDR) is well-suited for experimenting with advanced wireless communication systems, as it allows to alter the architecture promptly while obtaining high performance.…

Hardware Architecture · Computer Science 2023-05-24 Thijs Havinga , Xianjun Jiao , Wei Liu , Ingrid Moerman

Sequence alignments are fundamental to bioinformatics which has resulted in a variety of optimized implementations. Unfortunately, the vast majority of them are hand-tuned and specific to certain architectures and execution models. This not…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-17 André Müller , Bertil Schmidt , Andreas Hildebrandt , Richard Membarth , Roland Leißa , Matthis Kruse , Sebastian Hack

There is a large body of legacy scientific code written in languages like Fortran that is not optimised to get the best performance out of heterogeneous acceleration devices like GPUs and FPGAs, and manually porting such code into parallel…

Performance · Computer Science 2019-01-25 Wim Vanderbauwhede , Syed Waqar Nabi

FPGAs are commonly used to accelerate domain-specific algorithmic implementations, as they can achieve impressive performance boosts, are reprogrammable and exhibit minimal power consumption. In this work, the SqueezeNet DCNN is accelerated…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Panagiotis G. Mousouliotis , Konstantinos L. Panayiotou , Emmanouil G. Tsardoulias , Loukas P. Petrou , Andreas L. Symeonidis

Photoacoustic (PA) imaging has been widely applied in both preclinical and clinical applications. With a significantly increasing number of data acquisition channels, fast and high-quality image reconstruction for real-time PA imaging is an…

Medical Physics · Physics 2024-08-20 Zijian Gao , Yuting Shen , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

Fine-tuning large-scale pretrained models is prohibitively expensive in terms of computational and memory costs. LoRA, as one of the most popular Parameter-Efficient Fine-Tuning (PEFT) methods, offers a cost-effective alternative by…

Machine Learning · Computer Science 2024-07-17 Shaowen Wang , Linxi Yu , Jian Li

FPGAs provide a flexible and efficient platform to accelerate rapidly-changing algorithms for computer vision. The majority of existing work focuses on accelerating image classification, while other fundamental vision problems, including…

Image and Video Processing · Electrical Eng. & Systems 2020-03-25 Qijing Huang , Dequan Wang , Yizhao Gao , Yaohui Cai , Zhen Dong , Bichen Wu , Kurt Keutzer , John Wawrzynek

Genomics is the foundation of precision medicine, global food security and virus surveillance. Exact-match is one of the most essential operations widely used in almost every step of genomics such as alignment, assembly, annotation, and…

Hardware Architecture · Computer Science 2021-01-15 Lei Jiang , Farzaneh Zokaee

Intensive computation is entering data centers with multiple workloads of deep learning. To balance the compute efficiency, performance, and total cost of ownership (TCO), the use of a field-programmable gate array (FPGA) with…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Xiaoyu Yu , Yuwei Wang , Jie Miao , Ephrem Wu , Heng Zhang , Yu Meng , Bo Zhang , Biao Min , Dewei Chen , Jianlin Gao

Image feature extraction and matching is a fundamental but computation intensive task in machine vision. This paper proposes a novel FPGA-based embedded system to accelerate feature extraction and matching. It implements SURF feature point…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Qi Ni , Fei Wang , Ziwei Zhao , Peng Gao

Client heterogeneity poses significant challenges to the performance of Quantum Federated Learning (QFL). To overcome these limitations, we propose a new approach leveraging deep unfolding, which enables clients to autonomously optimize…

Machine Learning · Computer Science 2025-06-26 Shanika Iroshi Nanayakkara , Shiva Raj Pokhrel

FP8 low-precision formats have gained significant adoption in Transformer inference and training. However, existing digital compute-in-memory (DCIM) architectures face challenges in supporting variable FP8 aligned-mantissa bitwidths, as…

Hardware Architecture · Computer Science 2026-05-19 Liang Zhao , Kunming Shao , Zhipeng Liao , Xijie Huang , Tim Kwang-Ting Cheng , Chi-Ying Tsui , Yi Zou

Neuromorphic accelerators promise unparalleled energy efficiency and computational density for spiking neural networks (SNNs), especially in edge intelligence applications. However, most existing platforms exhibit rigid architectures with…

Hardware Architecture · Computer Science 2026-02-23 Mohammad Farahani , Mohammad Rasoul Roshanshah , Saeed Safari

With the development of hardware-optimized deployment of spiking neural networks (SNNs), SNN processors based on field-programmable gate arrays (FPGAs) have become a research hotspot due to their efficiency and flexibility. However,…

Neural and Evolutionary Computing · Computer Science 2026-01-06 Hou Yue , Xiang Shuiying , Zou Tao , Huang Zhiquan , Shi Shangxuan , Guo Xingxing , Zhang Yahui , Zheng Ling , Hao Yue

Motivation: Protein-to-genome alignment is critical to annotating genes in non-model organisms. While there are a few tools for this purpose, all of them were developed over ten years ago and did not incorporate the latest advances in…

Genomics · Quantitative Biology 2022-12-29 Heng Li

The acceleration of pruned Deep Neural Networks (DNNs) on edge devices such as Microcontrollers (MCUs) is a challenging task, given the tight area- and power-constraints of these devices. In this work, we propose a three-fold contribution…

Machine Learning · Computer Science 2025-03-20 Francesco Daghero , Daniele Jahier Pagliari , Francesco Conti , Luca Benini , Massimo Poncino , Alessio Burrello

Today, artificial neural networks are one of the major innovators pushing the progress of machine learning. This has particularly affected the development of neural network accelerating hardware. However, since most of these architectures…

Hardware Architecture · Computer Science 2021-02-12 Simon Pfenning , Philipp Holzinger , Marc Reichenbach

We propose a lightweight data structure for indexing and querying collections of NGS reads data in main memory. The data structure supports the interface proposed in the pioneering work by Philippe et al. for counting and locating $k$-mers…

Data Structures and Algorithms · Computer Science 2017-03-03 Tomasz Kowalski , Szymon Grabowski , Sebastian Deorowicz
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