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The time-dependent density functional theory (TDDFT) provides a unified description of the structure and reaction. The linear approximation leads to the random-phase approximation (RPA) which is capable of describing a variety of collective…

Nuclear Theory · Physics 2016-05-09 Kai Wen , Kouhei Washiyama , Ni Fang , Takashi Nakatsukasa

The computation of bounce action in a phase transition involves solving partial differential equations, inherently introducing non-negligible numerical uncertainty. Deriving characteristic temperatures and properties of this transition…

High Energy Physics - Phenomenology · Physics 2025-10-14 Ligong Bian , Hongxin Wang , Yang Xiao , Ji-Chong Yang , Jin Min Yang , Yang Zhang

We implemented a gradient-based algorithm for transition state search which uses Gaussian process regression. Besides a description of the algorithm, we provide a method to find the starting point for the optimization if only the reactant…

Chemical Physics · Physics 2020-09-15 Alexander Denzel , Johannes Kästner

Deep learning has advanced efficient chemical process simulations on the surfaces, accelerating high-throughput materials screening and rational design in heterogeneous catalysis, energy storage and conversion, and gas separation. However,…

Disordered Systems and Neural Networks · Physics 2026-03-12 Zhihao Zhang , Xiao-Ming Cao

Reaction barriers are a crucial ingredient for first principles based computational retro-synthesis efforts as well as for comprehensive reactivity assessments throughout chemical compound space. While extensive databases of experimental…

A fast method is developed for calculating the Random-Phase-Approximation (RPA) correlation energy for density functional theory. The correlation energy is given by a trace over a projected RPA response matrix and the trace is taken by a…

Chemical Physics · Physics 2013-01-01 Daniel Neuhauser , Eran Rabani , Roi Baer

Accurately modeling chemical reactions in molecular dynamics simulations requires detailed pre- and post-reaction templates, often created through labor-intensive manual workflows. This work introduces a Python-based algorithm that…

Computational Engineering, Finance, and Science · Computer Science 2025-07-24 Julian Konrad , Robert Meißner

Accurately determining resonance frequencies and quality factors (Q) is crucial in accelerator physics and radiofrequency engineering, as these factors have direct impacts on system design, operational stability, and research results. The…

Accelerator Physics · Physics 2025-10-08 Kerem Semiz

The analysis of non-equilibrium steady states of biochemical reaction networks relies on finding the configurations of fluxes and chemical potentials satisfying stoichiometric (mass balance) and thermodynamic (energy balance) constraints.…

Molecular Networks · Quantitative Biology 2011-07-13 Daniele De Martino , Matteo Figliuzzi , Andrea De Martino , Enzo Marinari

Next generation architectures necessitate a shift away from traditional workflows in which the simulation state is saved at prescribed frequencies for post-processing analysis. While the need to shift to in~situ workflows has been…

Computational Engineering, Finance, and Science · Computer Science 2015-08-20 Maher Salloum , Janine C. Bennett , Ali Pinar , Ankit Bhagatwala , Jacqueline H. Chen

The Pixel Array (PA) Method, originally introduced by Spivak et. al., is a fast method for solving nonlinear or linear systems. One of its distinguishing features is that it presents all solutions within a bounding box, represented by a…

Analysis of PDEs · Mathematics 2018-08-07 Cynthia T. Liu , David I. Spivak

Learning robotic manipulation policies through supervised learning from demonstrations remains challenging when policies encounter execution variations not explicitly covered during training. While incorporating historical context through…

Robotics · Computer Science 2026-03-10 Giovanni Minelli , Giulio Turrisi , Victor Barasuol , Claudio Semini

Understanding the movement patterns of objects (e.g., humans and vehicles) in a city is essential for many applications, including city planning and management. This paper proposes a method for predicting future city-wide crowd flows by…

Machine Learning · Computer Science 2023-10-05 Chung Park , Junui Hong , Cheonbok Park , Taesan Kim , Minsung Choi , Jaegul Choo

Accelerating finite automata processing is critical for advancing real-time analytic in pattern matching, data mining, bioinformatics, intrusion detection, and machine learning. Recent in-memory automata accelerators leveraging SRAMs and…

Hardware Architecture · Computer Science 2021-12-02 Yi Huang , Zhiyu Chen , Dai Li , Kaiyuan Yang

Nonlinear frequency response analysis is a widely used method for determining system dynamics in the presence of nonlinearities. In dusty plasmas, the plasma-grain interaction (e.g., grain charging fluctuations) can be characterized by a…

Plasma Physics · Physics 2020-10-26 Zhiyue Ding , Lorin S. Matthews , Truell W. Hyde

We present a fast computational method to efficiently screen enzyme activity. In the presented method, the effect of mutations on the barrier height of an enzyme-catalysed reaction can be computed within 24 hours on roughly 10 processors.…

Chemical Physics · Physics 2013-09-16 Martin R. Hediger , Luca De Vico , Allan Svendsen , Werner Besenmatter , Jan H. Jensen

First principles calculations based on density functional theory are having an incerasing impact on our understanding of molecule-surface interactions. For example, calculations of the multi-dimensional potential energy surface have…

Materials Science · Physics 2007-05-23 O. Gulseren , D. M. Bird , S. E. Humphreys

Fast and accurate protein structure prediction is one of the major challenges in structural biology, biotechnology and molecular biomedicine. These fields require 3D protein structures for rational design of proteins with improved or novel…

Data Analysis, Statistics and Probability · Physics 2013-11-14 Lars A. Bratholm

The task of locating first order saddle points on high-dimensional surfaces describing the variation of energy as a function of atomic coordinates is an essential step for identifying the mechanism and estimating the rate of thermally…

Chemical Physics · Physics 2025-07-24 Rohit Goswami , Maxim Masterov , Satish Kamath , Alejandro Peña-Torres , Hannes Jónsson

We propose an adiabatic reweighting algorithm for computing the free energy along an external parameter from adaptive molecular dynamics simulations. The adaptive bias is estimated using Bayes identity and information from all the sampled…

Statistical Mechanics · Physics 2014-04-08 Lingling Cao , Gabriel Stoltz , Tony Lelièvre , Mihai-Cosmin Marinica , Manuel Athènes