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Multi-omic datasets offer opportunities for improved biomarker discovery in cancer research, but their high dimensionality and limited sample sizes make identifying compact and effective biomarker panels challenging. Feature selection in…

Genomics · Quantitative Biology 2026-04-02 Luca Cattelani , Vittorio Fortino

We consider the scenario where important signals are not strong enough to be separable from a large amount of noise. Such weak signals commonly exist in large-scale data analysis and play vital roles in many biomedical applications.…

Methodology · Statistics 2022-01-26 X. Jessie Jeng , Yifei Hu

The feature subset selection problem aims at selecting the relevant subset of features to improve the performance of a Machine Learning (ML) algorithm on training data. Some features in data can be inherently noisy, costly to compute,…

Neural and Evolutionary Computing · Computer Science 2022-05-04 Ayaz Ur Rehman , Anas Nadeem , Muhammad Zubair Malik

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

Computation and Language · Computer Science 2022-01-13 Haoran Shi , Pengtao Xie , Zhiting Hu , Ming Zhang , Eric P. Xing

In this study, we propose a machine learning-based method for noise reduction and disease-causing gene feature extraction in gene sequencing DeepSeqDenoise algorithm combines CNN and RNN to effectively remove the sequencing noise, and…

Machine Learning · Computer Science 2025-05-27 Weichen Si , Yihao Ou , Zhen Tian

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Driven by new software development processes and testing in clouds, system and integration testing nowadays tends to produce enormous number of alarms. Such test alarms lay an almost unbearable burden on software testing engineers who have…

Software Engineering · Computer Science 2017-03-03 He Jiang , Xiaochen Li , Zijiang Yang , Jifeng Xuan

False alerts due to misconfigured/ compromised IDS in ICS networks can lead to severe economic and operational damage. To solve this problem, research has focused on leveraging deep learning techniques that help reduce false alerts.…

Artificial Intelligence · Computer Science 2022-03-14 Abhijeet Sahu , Katherine Davis

Feature Selection is a crucial procedure in Data Science tasks such as Classification, since it identifies the relevant variables, making thus the classification procedures more interpretable, cheaper in terms of measurement and more…

Machine Learning · Statistics 2024-01-17 Sandra Benítez-Peña , Rafael Blanquero , Emilio Carrizosa , Pepa Ramírez-Cobo

The analysis of electroencephalogram (EEG) waves is of critical importance for the diagnosis of sleep disorders, such as sleep apnea and insomnia, besides that, seizures, epilepsy, head injuries, dizziness, headaches and brain tumors. In…

Neural and Evolutionary Computing · Computer Science 2019-06-12 Icaro Marcelino Miranda , Claus Aranha , Marcelo Ladeira

In this paper, we propose an anomaly detection algorithm for machine sounds with a deep complex network trained by self-supervision. Using the fact that phase continuity information is crucial for detecting abnormalities in time-series…

Audio and Speech Processing · Electrical Eng. & Systems 2023-12-22 Miseul Kim , Minh Tri Ho , Hong-Goo Kang

The pattern of state changes in a biomedical time series can be related to health or disease. This work presents a principled approach for selecting a changepoint detection algorithm for a specific task, such as disease classification.…

Machine Learning · Computer Science 2024-04-22 Ayse Cakmak , Erik Reinertsen , Shamim Nemati , Gari D. Clifford

Sophisticated automatic incident detection (AID) technology plays a key role in contemporary transportation systems. Though many papers were devoted to study incident classification algorithms, few study investigated how to enhance feature…

Machine Learning · Computer Science 2016-11-18 Jimmy SJ. Ren , Wei Wang , Jiawei Wang , Stephen Liao

Feature selection is one of the most relevant processes in any methodology for creating a statistical learning model. Usually, existing algorithms establish some criterion to select the most influential variables, discarding those that do…

Machine Learning · Statistics 2024-05-10 Carlos Sebastián , Carlos E. González-Guillén

Artifacts are a common problem in physiological time series collected from intensive care units (ICU) and other settings. They affect the quality and reliability of clinical research and patient care. Manual annotation of artifacts is…

Machine Learning · Computer Science 2024-08-06 Hollan Haule , Ian Piper , Patricia Jones , Chen Qin , Tsz-Yan Milly Lo , Javier Escudero

Accurately labeling biomedical data presents a challenge. Traditional semi-supervised learning methods often under-utilize available unlabeled data. To address this, we propose a novel reliability-based training data cleaning method…

Machine Learning · Computer Science 2023-09-15 Xianghao Zhan , Qinmei Xu , Yuanning Zheng , Guangming Lu , Olivier Gevaert

Heart disease is the number one killer, and ECGs can assist in the early diagnosis and prevention of deadly outcomes. Accurate ECG interpretation is critical in detecting heart diseases; however, they are often misinterpreted due to a lack…

Machine Learning · Computer Science 2021-10-29 Dharma KC , Chicheng Zhang , Chris Gniady , Parth Sandeep Agarwal , Sushil Sharma

Modern bio-technologies have produced a vast amount of high-throughput data with the number of predictors far greater than the sample size. In order to identify more novel biomarkers and understand biological mechanisms, it is vital to…

Machine Learning · Statistics 2018-05-18 Kevin He , Jian Kang , Hyokyoung Grace Hong , Ji Zhu , Yanming Li , Huazhen Lin , Han Xu , Yi Li

In the high dimensional regression analysis when the number of predictors is much larger than the sample size, an important question is to select the important variable which are relevant to the response variable of interest. Variable…

Methodology · Statistics 2023-01-09 Pengsheng Ji , Zhigen Zhao

Epilepsy is a well-known neuronal disorder that can be identified by interpretation of the electroencephalogram (EEG) signal. Usually, the length of an EEG signal is quite long which is challenging to interpret manually. In this work, we…

Machine Learning · Computer Science 2019-03-07 Md Mursalin , Syed Shamsul Islam , Md Kislu Noman , Adel Ali Al-Jumaily