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The minimum description length (MDL) principle states that the best model to account for some data minimizes the sum of the lengths, in bits, of the descriptions of the model and the residual error. The description length is thus a…

Quantitative Methods · Quantitative Biology 2015-07-21 Peter T. Hraber , Bette T. Korber , Steven Wolinsky , Henry A. Erlich , Elizabeth A. Trachtenberg , Thomas B. Kepler

The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised…

In this paper we explore different regression models based on Clusterwise Linear Regression (CLR). CLR aims to find the partition of the data into $k$ clusters, such that linear regressions fitted to each of the clusters minimize overall…

Machine Learning · Computer Science 2018-05-01 Igor Gitman , Jieshi Chen , Eric Lei , Artur Dubrawski

Incidence estimation of HIV infection can be performed using recent infection testing algorithm (RITA) results from a cross-sectional sample. This allows practitioners to understand population trends in the HIV epidemic without having to…

Methodology · Statistics 2023-09-13 Marlena Bannick , Deborah Donnell , Richard Hayes , Oliver Laeyendecker , Fei Gao

A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The…

Neurons and Cognition · Quantitative Biology 2017-05-09 Javier Rasero , Mario Pellicoro , Leonardo Angelini , Jesus M. Cortes , Daniele Marinazzo , Sebastiano Stramaglia

Accurate identification and localization of the vertebrae in CT scans is a critical and standard preprocessing step for clinical spinal diagnosis and treatment. Existing methods are mainly based on the integration of multiple neural…

Image and Video Processing · Electrical Eng. & Systems 2020-01-03 Chunli Qin , Demin Yao , Han Zhuang , Hui Wang , Yonghong Shi , Zhijian Song

This paper considers a network of sensors without fusion center that may be difficult to set up in applications involving sensors embedded on autonomous drones or robots. In this context, this paper considers that the sensors must perform a…

Statistics Theory · Mathematics 2017-06-13 Dominique Pastor , Elsa Dupraz , François-Xavier Socheleau

Cloud computing data centers are growing in size and complexity to the point where monitoring and management of the infrastructure become a challenge due to scalability issues. A possible approach to cope with the size of such data centers…

Machine Learning · Computer Science 2019-03-07 Matteo Stefanini , Riccardo Lancellotti , Lorenzo Baraldi , Simone Calderara

The new coronavirus has caused more than one million deaths and continues to spread rapidly. This virus targets the lungs, causing respiratory distress which can be mild or severe. The X-ray or computed tomography (CT) images of lungs can…

Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are starting to be used as markers to improve prognosis or…

Genomics · Quantitative Biology 2008-01-22 Franck Rapaport , Emmanuel Barillot , Jean-Philippe Vert

Introduction. Can the infection due to the human immunodeficiency virus type 1 induce a change in the differentiation status or process in T cells?. Methods. We will consider two stochastic Markov chain models, one which will describe the…

Molecular Networks · Quantitative Biology 2021-02-09 Alfonso Vivanco-Lira , José-Raúl Nieto-Saucedo

Clustering of time series based on their underlying dynamics is keeping attracting researchers due to its impacts on assisting complex system modelling. Most current time series clustering methods handle only scalar time series, treat them…

Machine Learning · Statistics 2025-05-21 Zuogong Yue , Xinyi Wang , Victor Solo

Like many chronic diseases, human immunodeficiency virus (HIV) is managed over time at regular clinic visits. At each visit, patient features are assessed, treatments are prescribed, and a subsequent visit is scheduled. There is a need for…

Methodology · Statistics 2024-10-31 Arman Oganisian , Joseph Hogan , Edwin Sang , Allison DeLong , Ben Mosong , Hamish Fraser , Ann Mwangi

This study develops a pattern recognition method that identifies patterns based on their similarity and their association with the outcome of interest. The practical purpose of developing this pattern recognition method is to group…

Machine Learning · Computer Science 2020-11-20 Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Gholamreza Haffari , Behrooz Hassani-Mahmooei

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

This study investigates the heterogeneity in survival times among COVID-19 patients with Heart Failure (HF) hospitalized in the Lombardy region of Italy during the pandemic. To address this, we propose a novel mixture model for…

Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…

Machine Learning · Computer Science 2024-12-31 Anand Karna , Naina Khan , Rahul Rauniyar , Prashant Giridhar Shambharkar

This paper explores the use of clustering methods and machine learning algorithms, including Natural Language Processing (NLP), to identify and classify problems identified in credit risk models through textual information contained in…

Machine Learning · Computer Science 2023-06-05 Szymon Lis , Mariusz Kubkowski , Olimpia Borkowska , Dobromił Serwa , Jarosław Kurpanik

Applying a ML approach to the temporal variability of the Spike protein sequence enables us to identify, classify and track emerging virus variants. Our analysis is unbiased, in the sense that it does not require any prior knowledge of the…

Decision-makers frequently must choose a single action from a finite set of alternatives -- for example, physicians selecting a treatment, investors choosing a portfolio risk level, or judges determining sentences. To improve outcomes,…

Applications · Statistics 2026-05-19 Raphaël Langevin
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