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Operational semantics have been enormously successful, in large part due to its flexibility and simplicity, but they are not compositional. Denotational semantics, on the other hand, are compositional but the lattice-theoretic models are…

Programming Languages · Computer Science 2017-10-24 Jeremy G. Siek

Recent work has shown that we can dramatically improve the performance of computer games and simulations through declarative processing: Character AI can be written in an imperative scripting language which is then compiled to relational…

Databases · Computer Science 2009-09-15 Benjamin Sowell , Alan Demers , Johannes Gehrke , Nitin Gupta , Haoyuan Li , Walker White

To celebrate Hans Frauenfelder's achievements, we examine energy(-like) "landscapes" for complex living systems. Energy landscapes summarize all possible dynamics of some physical systems. Energy(-like) landscapes can explain some…

Quantitative Methods · Quantitative Biology 2021-10-18 Lars Koopmans , Hyun Youk

The mathematical formalisms used to model biological systems induce both latent and ambiguous assumptions that can limit or distort their representational capabilities. Developing formalisms that can represent systems more precisely is…

Quantitative Methods · Quantitative Biology 2026-05-25 Léo Diaz , Sean T. Vittadello , Michael P. H. Stumpf

Procedural models (i.e. symbolic programs that output visual data) are a historically-popular method for representing graphics content: vegetation, buildings, textures, etc. They offer many advantages: interpretable design parameters,…

Deep generative models are able to suggest new organic molecules by generating strings, trees, and graphs representing their structure. While such models allow one to generate molecules with desirable properties, they give no guarantees…

Machine Learning · Computer Science 2019-12-05 John Bradshaw , Brooks Paige , Matt J. Kusner , Marwin H. S. Segler , José Miguel Hernández-Lobato

In this introductory article we present the basics of an approach to implementing computational interpreting of natural language aiming to model the meanings of words and phrases. Unlike other approaches, we attempt to define the meanings…

Computation and Language · Computer Science 2019-08-12 Michael Kapustin , Pavlo Kapustin

Our goal is to define an algebraic language for reasoning about non-deterministic computations. Towards this goal, we introduce an algebra of string-to-string transductions. Specifically, it is an algebra of partial functions on words over…

Logic in Computer Science · Computer Science 2023-11-22 Eugenia Ternovska

The role of the descriptor system representation as basis for reliable numerical computations for system analysis and synthesis, and in particular, for the manipulation of rational matrices, is discussed and available robust numerical…

Systems and Control · Electrical Eng. & Systems 2021-06-08 Andreas Varga

Many real-world dynamic systems, both natural and artificial, are understood to be performing computations. For artificial dynamic systems, explicitly designed to perform computation - such as digital computers - by construction, we can…

Computational Physics · Physics 2026-02-24 David H. Wolpert , Jan Korbel

This paper is placed at the intersection-point between the study of theoretical computational models aimed at capturing the essence of genetic regulatory networks and the field of Artificial Embryology (or Computational Development). A…

Adaptation and Self-Organizing Systems · Physics 2016-10-12 Alessandro Fontana

Massive data collection holds the promise of a better understanding of complex phenomena and, ultimately, better decisions. Representation learning has become a key driver of deep learning applications, as it allows learning latent spaces…

Machine Learning · Computer Science 2025-11-10 Caroline Uhler , Jiaqi Zhang

Agent-based modeling is a computational dynamic modeling technique that may be less familiar to some readers. Agent-based modeling seeks to understand the behaviour of complex systems by situating agents in an environment and studying the…

Multiagent Systems · Computer Science 2023-04-19 G. Wade McDonald , Nathaniel D. Osgood

Previous work has presented our ongoing e orts to define a "reference semantics" for the UML, that is, a mathematically defined system model that is envisaged to cover all of the UML eventually, and that also carefully avoids the…

Software Engineering · Computer Science 2014-09-24 Maria Victoria Cengarle , Jürgen Dingel , Hans Grönninger , Bernhard Rumpe

Large language models have shown unprecedented abilities in generating linguistically coherent and syntactically correct natural language output. However, they often return incorrect and inconsistent answers to input questions. Due to the…

Databases · Computer Science 2023-12-27 Jasmin Mousavi , Arash Termehchy

In this chapter we provide an overview of computational modeling for semantic change using large and semi-large textual corpora. We aim to provide a key for the interpretation of relevant methods and evaluation techniques, and also provide…

Computation and Language · Computer Science 2023-04-14 Nina Tahmasebi , Haim Dubossarsky

The growing complexity of modern practical problems puts high demands on the mathematical modelling. Given that various models can be used for modelling one physical phenomenon, the role of model comparison and model choice becomes…

Category Theory · Mathematics 2021-08-16 Dmitrii Legatiuk

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

Biomolecules · Quantitative Biology 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

We describe a mathematical structure that can give extensional denotational semantics to higher-order probabilistic programs. It is not limited to discrete probabilities, and it is compatible with integration in a way the models that have…

Logic in Computer Science · Computer Science 2021-04-14 Guillaume Geoffroy

In material science, models are derived to predict emergent material properties (e.g. elasticity, strength, conductivity) and their relations to processing conditions. A major drawback is the calibration of model parameters that depend on…

Neural and Evolutionary Computing · Computer Science 2021-11-22 Gabriel Kronberger , Evgeniya Kabliman , Johannes Kronsteiner , Michael Kommenda
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