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X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

We consider a density estimation problem arising in nuclear physics. Gamma photons are impinging on a semiconductor detector, producing pulses of current. The integral of this pulse is equal to the total amount of charge created by the…

Statistics Theory · Mathematics 2007-06-13 Eric Moulines , Francois Roueff , Antoine Souloumiac , Thomas Trigano

We have developed a simulation-based method of spectral analysis for pile-up affected data of X-ray CCDs without any loss of photon statistics. As effects of the photon pile-up appear as complicated nonlinear detector responses, we employ a…

Instrumentation and Methods for Astrophysics · Physics 2022-03-14 Tsubasa Tamba , Hirokazu Odaka , Aya Bamba , Hiroshi Murakami , Koji Mori , Kiyoshi Hayashida , Yukikatsu Terada , Tsunefumi Mizuno , Masayoshi Nobukawa

Photon counting detectors (PCDs) bring valuable advantages to diagnostic computed tomography (CT), including lower noise and higher resolution than energy integrating detectors. However, there are still several nonideal factors preventing…

Medical Physics · Physics 2024-03-27 Shengzi Zhao , Le Shen , Yuxing Xing

Microdosimetry investigates the energy deposition of ionizing radiation at microscopic scales, beyond the assessment capabilities of macroscopic dosimetry. This contributes to an understanding of the biological response in radiobiology,…

A formalism for treating the pile-up produced in solid-state detectors by laser-driven pulsed x-ray sources has been developed. It allows the direct use of x-ray spectroscopy without artificially decreasing the number of counts in the…

Instrumentation and Detectors · Physics 2018-06-01 Guillermo Hernández , Francisco Fernández

Pulse-pileup affects most photon counting systems and occurs when photon detections occur faster than the detector's registration and recovery time. At high input rates, shaped pulses interfere and the source spectrum, as well as intensity…

Instrumentation and Methods for Astrophysics · Physics 2013-04-30 Vandiver Chaplin , Narayana Bhat , Michael Briggs , Valerie Connaughton

Improving the efficiency of current neural networks and modeling them in biological neural systems have become popular research directions in recent years. Pulse-coupled neural network (PCNN) is a well applicated model for imitating the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Haoran Liu , Mingzhe Liu , Peng Li , Jiahui Wu , Xin Jiang , Zhuo Zuo , Bingqi Liu

Research in neural models inspired by mammal's visual cortex has led to many spiking neural networks such as pulse-coupled neural networks (PCNNs). These models are oscillating, spatio-temporal models stimulated with images to produce…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Nurul Rafi , Pablo Rivas

An essential metric for the quality of a particle-identification experiment is its statistical power to discriminate between signal and background. Pulse shape discrimination (PSD) is a basic method for this purpose in many nuclear,…

Instrumentation and Detectors · Physics 2024-05-17 Shubham Dutta , Sayan Ghosh , Satyaki Bhattacharya , Satyajit Saha

-Purpose: A neural network estimator to process x-ray spectral measurements from photon counting detectors with pileup. The estimator is used with an expansion of the attenuation coefficient as a linear combination of functions of energy…

Medical Physics · Physics 2017-02-06 Robert Alvarez

Microdosimetry provides a superior characterization of the radiation field compared to conventional LET-based methodology, and for this reason it has become increasingly attractive for quality assurance in particle therapy. However, the…

Medical Physics · Physics 2025-04-08 E. Pierobon , M. Missiaggia , F. G. Cordoni , C. La Tessa

As photon counting detectors are being explored for medical and industrial imaging applications, there is a critical need to understand spectral characteristics of scattered x-ray photons. Scattered radiation is detrimental to x-ray imaging…

Medical Physics · Physics 2022-12-14 Cale E. Lewis , Mini Das

Using Time-Correlated Single Photon Counting (TCSPC) for the purpose of fluorescence lifetime measurements is usually limited in speed due to pile-up. With modern instrumentation this limitation can be lifted significantly but some…

Data Analysis, Statistics and Probability · Physics 2018-05-23 Matthias Patting , Paja Reisch , Marcus Sackrow , Rhys Dowler , Marcelle Koenig , Michael Wahl

A Pixelized Photon Detector (PPD) is a generic name for the semiconductor devices operated in the Geiger-mode, such as Silicon PhotoMultiplier and Multi-Pixel Photon Counter, which has high photon counting capability. While the internal…

Instrumentation and Detectors · Physics 2009-11-13 H. Otono , H. Oide , S. Yamashita , T. Yoshioka

Silicon drift detectors (SDDs) revolutionized spectroscopy in fields as diverse as geology and dentistry. For a subset of experiments at ultra-fast, x-ray free-electron lasers (FELs), SDDs can make substantial contributions. Often the…

We consider the counting rate estimation of an unknown radioactive source, which emits photons at times modeled by an homogeneous Poisson process. A spectrometer converts the energy of incoming photons into electrical pulses, whose number…

Methodology · Statistics 2015-06-04 Y. Sepulcre , T. Trigano , Y. Ritov

Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…

A multi-imaging strategy is proposed and experimentally tested to improve the accuracy of photon counting with an electron multiplying charge-coupled device (EMCCD), by taking into account the random nature of its on-chip gain and the…

Astrophysics · Physics 2009-11-13 Eric Lantz , Jean Luc Blanchet , Luca Furfaro , Fabrice Devaux

X-ray photon-counting detector (PCD) offers low noise, high resolution, and spectral characterization, representing a next generation of CT and enabling new biomedical applications. It is well known that involuntary patient motion may…

Medical Physics · Physics 2022-10-20 Mengzhou Li , Chiara Lowe , Anthony Butler , Phil Butler , Ge Wang
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