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Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

The inversion of linear systems is a fundamental step in many inverse problems. Computational challenges exist when trying to invert large linear systems, where limited computing resources mean that only part of the system can be kept in…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-05 Yushan Gao , Thomas Blumensath

We propose algorithms based on an optimisation method for inverse multislice ptychography in, e.g. electron microscopy. The multislice method is widely used to model the interaction between relativistic electrons and thick specimens. Since…

We consider inpainting in an unsupervised setting where there is neither access to paired nor unpaired training data. The only available information is provided by the uncomplete observations and the inpainting process statistics. In this…

Computer Vision and Pattern Recognition · Computer Science 2019-12-30 Arthur Pajot , Emmanuel de Bezenac , Patrick Gallinari

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Tomography can be used to reveal internal properties of a 3D object using any penetrating wave. Advanced tomographic imaging techniques, however, are vulnerable to both systematic and random errors associated with the experimental…

Numerical Analysis · Mathematics 2019-02-08 Anthony P. Austin , Zichao Wendy Di , Sven Leyffer , Stefan M. Wild

Classical methods for X-ray computed tomography are based on the assumption that the X-ray source intensity is known, but in practice, the intensity is measured and hence uncertain. Under normal operating conditions, when the exposure time…

Numerical Analysis · Mathematics 2017-07-17 Hari Om Aggrawal , Martin Skovgaard Andersen , Sean Rose , Emil Y. Sidky

In this paper, we study the missing sample recovery problem using methods based on sparse approximation. In this regard, we investigate the algorithms used for solving the inverse problem associated with the restoration of missed samples of…

Machine Learning · Statistics 2017-06-29 Amirhossein Javaheri , Hadi Zayyani , Farokh Marvasti

Novel Magnetic Resonance (MR) imaging modalities can quantify hemodynamics but require long acquisition times, precluding its widespread use for early diagnosis of cardiovascular disease. To reduce the acquisition times, reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Lauren Partin , Daniele E. Schiavazzi , Carlos A. Sing Long

Diffusion-based inpainting can reconstruct missing image areas with high quality from sparse data, provided that their location and their values are well optimised. This is particularly useful for applications such as image compression,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-24 Pascal Peter , Karl Schrader , Tobias Alt , Joachim Weickert

Electron tomography (ET) has become a standard technique for 3D characterization of materials at the nano-scale. Traditional reconstruction algorithms such as weighted back projection suffer from disruptive artifacts with insufficient…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Yi Jiang , Elliot Padgett , Robert Hovden , David A. Muller

Spectral computed tomography has received considerable interest in recent years since spectral measurements contain much richer information about the object of interest. In spectral computed tomography, we are interested in the energy…

Numerical Analysis · Mathematics 2022-03-04 Katrine O Bangsgaard , Genoveva Burca , Evelina Ametova , Martin S Andersen , Jakob S Jørgensen

Computed tomography is a widely used imaging modality with applications ranging from medical imaging to material analysis. One major challenge arises from the lack of scanning information at certain angles, resulting in distortion or…

This paper proposes a randomized optimization framework for constrained signal reconstruction, where the word "constrained" implies that data-fidelity is imposed as a hard constraint instead of adding a data-fidelity term to an objective…

Optimization and Control · Mathematics 2024-06-28 Shunsuke Ono

Recent CT Metal Artifacts Reduction (MAR) methods are often based on image-to-image convolutional neural networks for adjustment of corrupted sinograms or images themselves. In this paper, we are exploring the capabilities of a multi-domain…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Artem Pimkin , Alexander Samoylenko , Natalia Antipina , Anna Ovechkina , Andrey Golanov , Alexandra Dalechina , Mikhail Belyaev

The Diffuse Optical Tomography (DOT) has received considerable attention in the recent years in the field of biomedical imaging and disease detection. However, imaging through highly diffusive medium is a challenge and stability is always…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Tapan Das , P. K. Dutta

Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…

We present an alternative numerical reconstruction algorithm for direct tomographic reconstruction of a sample refractive indices from the measured intensities of its far-field coherent diffraction patterns. We formulate the well-known…

Computational Physics · Physics 2019-02-06 T. Ramos , Bastian E. Grønager , Martin Skovgaard Andersen , J. W. Andreasen

Using recent advances in generative artificial intelligence (AI) brought by diffusion models, this paper introduces a new synergistic method for spectral computed tomography (CT) reconstruction. Diffusion models define a neural network to…

Most existing learning-based methods for solving imaging inverse problems can be roughly divided into two classes: iterative algorithms, such as plug-and-play and diffusion methods leveraging pretrained denoisers, and unrolled architectures…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Matthieu Terris , Samuel Hurault , Maxime Song , Julian Tachella