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Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical…
Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive and prone to inter observer variability. Deep convolutional…
Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…
Medulloblastoma (MB) is a primary central nervous system tumor and the most common malignant brain cancer among children. Neuropathologists perform microscopic inspection of histopathological tissue slides under a microscope to assess the…
Clinical diagnostic and treatment decisions rely upon the integration of patient-specific data with clinical reasoning. Cancer presents a unique context that influence treatment decisions, given its diverse forms of disease evolution.…
Brain tumors present a grave risk to human life, demanding precise and timely diagnosis for effective treatment. Inaccurate identification of brain tumors can significantly diminish life expectancy, underscoring the critical need for…
Accurate and reliable brain tumor segmentation is a critical component in cancer diagnosis, treatment planning, and treatment outcome evaluation. Build upon successful deep learning techniques, a novel brain tumor segmentation method is…
Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However,…
Acute lymphoblastic leukemia (ALL) is a prevalent hematological malignancy in both pediatric and adult populations. Early and accurate detection with precise subtyping is essential for guiding therapy. Conventional workflows are complex,…
Early detection and accurate diagnosis are essential to improving patient outcomes. The use of convolutional neural networks (CNNs) for tumor detection has shown promise, but existing models often suffer from overparameterization, which…
Convolutional Neural Networks (CNNs) are propelling advances in a range of different computer vision tasks such as object detection and object segmentation. Their success has motivated research in applications of such models for medical…
Melanoma is a sort of skin cancer that starts in the cells known as melanocytes. It is more dangerous than other types of skin cancer because it can spread to other organs. Melanoma can be fatal if it spreads to other parts of the body.…
Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…
Prenatal ultrasound evaluates fetal growth and detects congenital abnormalities during pregnancy, but the examination of ultrasound images by radiologists requires expertise and sophisticated equipment, which would otherwise fail to improve…
Brain tumors are collections of abnormal cells that can develop into masses or clusters. Because they have the potential to infiltrate other tissues, they pose a risk to the patient. The main imaging technique used, MRI, may be able to…
Accurate segmentation of the optic disc (OD) and cup (OC)in fundus images from different datasets is critical for glaucoma disease screening. The cross-domain discrepancy (domain shift) hinders the generalization of deep neural networks to…
A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…
The rapid development in representation learning techniques such as deep neural networks and the availability of large-scale, well-annotated medical imaging datasets have to a rapid increase in the use of supervised machine learning in the…
Accurate segmentation of brain metastases (BMs) in MR image is crucial for the diagnosis and follow-up of patients. Methods based on deep convolutional neural networks (CNNs) have achieved high segmentation performance. However, due to the…
Purpose: Gliomas are the most common and aggressive type of brain tumors due to their infiltrative nature and rapid progression. The process of distinguishing tumor boundaries from healthy cells is still a challenging task in the clinical…