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In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

Despite deep convolutional neural networks boost the performance of image classification and segmentation in digital pathology analysis, they are usually weak in interpretability for clinical applications or require heavy annotations to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yongxiang Huang , Albert C. S. Chung

In minimally invasive surgery, surgical instrument localization is a crucial task for endoscopic videos, which enables various applications for improving surgical outcomes. However, annotating the instrument localization in endoscopic…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Rongfeng Wei , Jinlin Wu , Xuexue Bai , Ming Feng , Zhen Lei , Hongbin Liu , Zhen Chen

Within medical imaging, manual curation of sufficient well-labeled samples is cost, time and scale-prohibitive. To improve the representativeness of the training dataset, for the first time, we present an approach to utilize large amounts…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Fernando Navarro , Sailesh Conjeti , Federico Tombari , Nassir Navab

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhixiang Lu , Shijie Xu , Kaicheng Yan , Xuyue Cai , Chong Zhang , Yulong Li , Angelos Stefanidis , Anh Nguyen , Jionglong Su

Universal models for medical image segmentation, such as interactive and in-context learning (ICL) models, offer strong generalization but require extensive annotations. Interactive models need repeated user prompts for each image, while…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Jinyan Zhou , Jianfeng Cao , Hanyang Peng , Ting Ma

Weakly Supervised Object Detection (WSOD), using only image-level annotations to train object detectors, is of growing importance in object recognition. In this paper, we propose a novel deep network for WSOD. Unlike previous networks that…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Peng Tang , Xinggang Wang , Song Bai , Wei Shen , Xiang Bai , Wenyu Liu , Alan Yuille

Accurate and automatic analysis of breast MRI plays an important role in early diagnosis and successful treatment planning for breast cancer. Due to the heterogeneity nature, accurate diagnosis of tumors remains a challenging task. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Luyang Luo , Hao Chen , Xi Wang , Qi Dou , Huangjin Lin , Juan Zhou , Gongjie Li , Pheng-Ann Heng

Surgical tool localization is an essential task for the automatic analysis of endoscopic videos. In the literature, existing methods for tool localization, tracking and segmentation require training data that is fully annotated, thereby…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Armine Vardazaryan , Didier Mutter , Jacques Marescaux , Nicolas Padoy

We present an Expectation-Maximization (EM) Regularized Deep Learning (EMReDL) model for weakly supervised tumor segmentation. The proposed framework is tailored to glioblastoma, a type of malignant tumor characterized by its diffuse…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Chao Li , Wenjian Huang , Xi Chen , Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb

Weakly Supervised Object Localization (WSOL), which aims to localize objects by only using image-level labels, has attracted much attention because of its low annotation cost in real applications. Recent studies leverage the advantage of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Haotian Bai , Ruimao Zhang , Jiong Wang , Xiang Wan

The segmentation of endoscopic images plays a vital role in computer-aided diagnosis and treatment. The advancements in deep learning have led to the employment of numerous models for endoscopic tumor segmentation, achieving promising…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Lingcong Cai , Yun Li , Xiaomao Fan , Kaixuan Song , Ruxin Wang , Wenbin Lei

Weakly supervised learning has been rapidly advanced in biomedical image analysis to achieve pixel-wise labels (segmentation) from image-wise annotations (classification), as biomedical images naturally contain image-wise labels in many…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Ruining Deng , Quan Liu , Shunxing Bao , Aadarsh Jha , Catie Chang , Bryan A. Millis , Matthew J. Tyska , Yuankai Huo

Cell classification and counting in immunohistochemical cytoplasm staining images play a pivotal role in cancer diagnosis. Weakly supervised learning is a potential method to deal with labor-intensive labeling. However, the inconstant cell…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Shichuan Zhang , Chenglu Zhu , Honglin Li , Jiatong Cai , Lin Yang

Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Rocío del Amor , Laëtitia Launet , Adrián Colomer , Anaïs Moscardó , Andrés Mosquera-Zamudio , Carlos Monteagudo , Valery Naranjo

Accurate lesion classification in Wireless Capsule Endoscopy (WCE) images is vital for early diagnosis and treatment of gastrointestinal (GI) cancers. However, this task is confronted with challenges like tiny lesions and background…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Kunpeng Qiu , Zhiying Zhou , Yongxin Guo

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Melanoma is a curable aggressive skin cancer if detected early. Typically, the diagnosis involves initial screening with subsequent biopsy and histopathological examination if necessary. Computer aided diagnosis offers an objective score…

Computer Vision and Pattern Recognition · Computer Science 2018-04-12 Xin Yi , Ekta Walia , Paul Babyn

Purpose: Probe-based Confocal Laser Endomicroscopy (pCLE) enables performing an optical biopsy, providing real-time microscopic images, via a probe. pCLE probes consist of multiple optical fibres arranged in a bundle, which taken together…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Agnieszka Barbara Szczotka , Dzhoshkun Ismail Shakir , DanieleRavi , Matthew J. Clarkson , Stephen P. Pereira , Tom Vercauteren