Related papers: Dose Delivery Verification
Dose painting has been developed to modulate the required dose in the target area without increasing the toxicity in healthy areas. Apart from determining the accurate location and size of tumors, quantitative functional imaging can be used…
Proton therapy systems without a gantry can be more compact and less expensive in terms of capital cost, and therefore more available to a larger patient population. Would the advances in pencil beam scanning and robotics make gantry-less…
HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). In addition, the HollandPTC R&D…
Precision luminosity measurements are essential to determine the fundamental properties of the physics processes at the LHC. The estimation of the integrated luminosity at the CMS experiment requires absolute scale calibration of the…
We demonstrate a coherent quantum measurement for the determination of the degree of polarization (DOP). This method allows to measure the DOP in the presence of fast polarization state fluctuations, difficult to achieve with the typically…
We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…
Purpose: This is a theoretical simulation study for proof of concept of radiochromic film dosimetry to measure physical and biological doses without plan-based quenching correction for patient-specific quality assurance of carbon-ion…
Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and…
Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…
Anatomical motion and deformation pose challenges to the understanding of the delivered dose distribution during radiotherapy treatments. Hence, deformable image registration (DIR) algorithms are increasingly used to map contours and dose…
For the in vivo range verification in proton therapy, it has been tried to measure the spatial distribution of the prompt gammas generated by the proton-induced interactions with the close relationship with the proton dose distribution.…
This article proposes a new method to measure the proton detector efficiency for use in "beam" determinations of the free neutron lifetime. There is currently a 4{\sigma} disagreement between the "beam" and "storage" methods of measuring…
The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains challenging with several crucial aspects missing. This work…
In Chinese Spallation Neutron Source (CSNS), proton beam is used to hit metal tungsten target, and then high flux neutron are generated for experiments on instruments. For neutron flux spectrum correction, the current of proton beam is for…
Objective: To assess the accuracy and computational performance of a stochastic differential equation (SDE)--based model for proton beam dose calculation by benchmarking against Geant4 in simplified phantom geometries. Approach: Building on…
Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…
Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…
Proton therapy is nowadays becoming a wide spread clinical practice in cancer therapy and sophisticated treatment planning systems are routinely used to exploit at best the ballistic properties of charged particles. The information on the…
Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…
Technical Note describing studies, in 2011, of time resolved diode dosimetry in an anthropomorphic phantom at the Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, Boston, MA. This technique measures the water…