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Related papers: Dose Delivery Verification

200 papers

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

This paper describes the dose delivery system used at the Centro Nazionale di Adroterapia Oncologica (CNAO) for ion beam modulated scanning radiotherapy. CNAO Foundation, INFN and University of Torino have developed and commissioned a Dose…

PET imaging is a non-invasive technique for particle range verification in proton therapy. It is based on measuring the beta+ annihilations caused by nuclear interactions of the protons in the patient. In this work we present measurements…

Purpose: Highlight the distinctions, both in terms of concept and numerical values, of the various definitions that can be established for the dose rate in PBS proton therapy. Methods: In an in silico study, five definitions of the dose…

Medical Physics · Physics 2023-07-17 Sylvain Deffet , Valentin Hamaide , Edmond Sterpin

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

Due to the increasing complexity of radiotherapy delivery, accurate dose verification has become an essential part of the clinical treatment process. The purpose of this work was to develop an electronic portal image (EPI) based…

Medical Physics · Physics 2015-06-17 Reid W Townson , Sergei Zavgorodni

Standard dosimetry protocols exist for highly penetrating photon and particle beams used in the clinic and in research. However, these protocols cannot be directly applied to shallow penetration MeV-range ion beams. The Radiological…

Accelerator Physics · Physics 2022-02-23 Guy Garty , Andrew D. Harken , David J. Brenner

We compute, from first principles, the absolute dose or fluence distribution per incident proton charge in a known heterogeneous terrain exposed to known proton beams. The algorithm is equally amenable to scattered or scanned beams. All…

Medical Physics · Physics 2016-10-05 Bernard Gottschalk

Objective. Prompt-gamma imaging encompasses several approaches for online monitoring of beam range or deposited dose distribution in proton therapy. We test one of the imaging techniques - a coded mask approach - both experimentally and via…

The medical commissioning is an important step to bring a particle gantry into clinical operation for tumour treatments. This involves the parametrization and characterization of all relevant systems including the beam delivery, the patient…

Medical Physics · Physics 2018-04-25 David Meer

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…

Accelerator Physics · Physics 2025-06-25 Alexander A. Pryanichnikov , Dmitry Shwartz , Jon Feldmand , Joao Seco , Maria Francesca Spadea

Currently, radiobiology experiments using heavy ions at GANIL(Grand Accelerateur National d Ions Lourds) are conducted under the supervision of the CIMAP (Center for research on Ions, MAterials and Photonics). In this context, a new beam…

Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…

Medical Physics · Physics 2025-04-01 Magdalena Kołodziej

When treating moving tumors, the precise delivery of proton therapy by pencil beam scanning (PBS) is challenged by the interplay effect. Although several 4D-optimization methods have been proposed, what is the most beneficial motion…

Medical Physics · Physics 2025-01-29 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

Every radiotherapy center has to be equipped with real-time beam monitoring devices. In 2008, the medical application group from the Laboratory of Corpuscular Physics (LPC Caen) developed an Ionization Chamber in collaboration with the…

Instrumentation and Detectors · Physics 2015-06-16 C. Courtois , G. Boissonnat , C. Brusasco , J. Colin , D. Cussol , J. M. Fontbonne , B. Marchand , T. Mertens , S. De Neuter , J. Perronnel