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Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu

We propose an efficient inference method for switching nonlinear dynamical systems. The key idea is to learn an inference network which can be used as a proposal distribution for the continuous latent variables, while performing exact…

Machine Learning · Computer Science 2020-02-12 Zhe Dong , Bryan A. Seybold , Kevin P. Murphy , Hung H. Bui

Variational inference (VI) combined with data subsampling enables approximate posterior inference over large data sets, but suffers from poor local optima. We first formulate a deterministic annealing approach for the generic class of…

Machine Learning · Statistics 2016-05-31 Stephan Mandt , James McInerney , Farhan Abrol , Rajesh Ranganath , David Blei

Conformal prediction is a distribution-free technique for establishing valid prediction intervals. Although conventionally people conduct conformal prediction in the output space, this is not the only possibility. In this paper, we propose…

Machine Learning · Computer Science 2023-04-11 Jiaye Teng , Chuan Wen , Dinghuai Zhang , Yoshua Bengio , Yang Gao , Yang Yuan

Despite the frequent use of agent-based models (ABMs) for studying social phenomena, parameter estimation remains a challenge, often relying on costly simulation-based heuristics. This work uses variational inference to estimate the…

Computers and Society · Computer Science 2025-12-04 Jacopo Lenti , Fabrizio Silvestri , Gianmarco De Francisci Morales

Conditional inference on arbitrary subsets of variables is a core problem in probabilistic inference with important applications such as masked language modeling and image inpainting. In recent years, the family of Any-Order Autoregressive…

Machine Learning · Computer Science 2022-10-25 Andy Shih , Dorsa Sadigh , Stefano Ermon

Neural topic models have triggered a surge of interest in extracting topics from text automatically since they avoid the sophisticated derivations in conventional topic models. However, scarce neural topic models incorporate the word…

Artificial Intelligence · Computer Science 2021-05-24 Rui Wang , Deyu Zhou , Yuxuan Xiong , Haiping Huang

Probability density function estimation with weighted samples is the main foundation of all adaptive importance sampling algorithms. Classically, a target distribution is approximated either by a non-parametric model or within a parametric…

Machine Learning · Computer Science 2023-10-16 Julien Demange-Chryst , François Bachoc , Jérôme Morio , Timothé Krauth

Variational methods are employed in situations where exact Bayesian inference becomes intractable due to the difficulty in performing certain integrals. Typically, variational methods postulate a tractable posterior and formulate a lower…

Machine Learning · Statistics 2019-06-12 Nikolaos Gianniotis , Christoph Schnörr , Christian Molkenthin , Sanjay Singh Bora

Recently, a number of mostly $\ell_1$-norm regularized least squares type deterministic algorithms have been proposed to address the problem of \emph{sparse} adaptive signal estimation and system identification. From a Bayesian perspective,…

Variable selection techniques have become increasingly popular amongst statisticians due to an increased number of regression and classification applications involving high-dimensional data where we expect some predictors to be unimportant.…

Methodology · Statistics 2010-09-20 Anthony Lee , Francois Caron , Arnaud Doucet , Chris Holmes

Calcium imaging permits optical measurement of neural activity. Since intracellular calcium concentration is an indirect measurement of neural activity, computational tools are necessary to infer the true underlying spiking activity from…

Machine Learning · Statistics 2017-11-07 Artur Speiser , Jinyao Yan , Evan Archer , Lars Buesing , Srinivas C. Turaga , Jakob H. Macke

In this article, we propose a variational inference formulation of auto-associative memories, allowing us to combine perceptual inference and memory retrieval into the same mathematical framework. In this formulation, the prior probability…

Machine Learning · Computer Science 2022-10-18 Louis Annabi , Alexandre Pitti , Mathias Quoy

As modern neural networks get more complex, specifying a model with high predictive performance and sound uncertainty quantification becomes a more challenging task. Despite some promising theoretical results on the true posterior…

Machine Learning · Computer Science 2025-06-18 Alisa Sheinkman , Sara Wade

Amortized variational inference (AVI) replaces instance-specific local inference with a global inference network. While AVI has enabled efficient training of deep generative models such as variational autoencoders (VAE), recent empirical…

Machine Learning · Statistics 2018-07-25 Yoon Kim , Sam Wiseman , Andrew C. Miller , David Sontag , Alexander M. Rush

To build a flexible and interpretable model for document analysis, we develop deep autoencoding topic model (DATM) that uses a hierarchy of gamma distributions to construct its multi-stochastic-layer generative network. In order to provide…

Machine Learning · Computer Science 2020-06-17 Hao Zhang , Bo Chen , Yulai Cong , Dandan Guo , Hongwei Liu , Mingyuan Zhou

This paper presents a new parameter estimation algorithm for the adaptive control of a class of time-varying plants. The main feature of this algorithm is a matrix of time-varying learning rates, which enables parameter estimation error…

Optimization and Control · Mathematics 2021-11-18 Joseph E. Gaudio , Anuradha M. Annaswamy , Eugene Lavretsky , Michael A. Bolender

Variational inference is a powerful tool for approximate inference, and it has been recently applied for representation learning with deep generative models. We develop the variational Gaussian process (VGP), a Bayesian nonparametric…

Machine Learning · Statistics 2016-04-19 Dustin Tran , Rajesh Ranganath , David M. Blei

A weakly admissible mesh (WAM) on a continuum real-valued domain is a sequence of discrete grids such that the discrete maximum norm of polynomials on the grid is comparable to the supremum norm of polynomials on the domain. The asymptotic…

Numerical Analysis · Mathematics 2021-09-20 Yiming Xu , Akil Narayan

Highly expressive directed latent variable models, such as sigmoid belief networks, are difficult to train on large datasets because exact inference in them is intractable and none of the approximate inference methods that have been applied…

Machine Learning · Computer Science 2016-06-06 Andriy Mnih , Karol Gregor