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Electrical properties (EPs) of tissues, conductivity and permittivity, are modulated by the ionic and water content, which change in presence of pathologies. Information on tissues EPs can be used e.g. as an endogenous biomarker in…
Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…
In this paper, we propose a novel deep convolutional neural network (CNN)-based algorithm for solving ill-posed inverse problems. Regularized iterative algorithms have emerged as the standard approach to ill-posed inverse problems in the…
In clinical CT system, the x-ray tube emits polychromatic x-rays, and the x-ray detectors operate in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral equation. However,…
A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…
PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…
Deep learning networks have shown state-of-the-art performance in many image reconstruction problems. However, it is not well understood what properties of representation and learning may improve the generalization ability of the network.…
Positron Emission Tomography scan images are extensively used in radiotherapy planning, clinical diagnosis, assessment of growth and treatment of a tumor. These all rely on fidelity and speed of detection and delineation algorithm. Despite…
Ultrasound imaging is caught between the quest for the highest image quality, and the necessity for clinical usability. Our contribution is two-fold: First, we propose a novel fully convolutional neural network for ultrasound…
Image reconstruction under multiple light scattering is crucial in a number of applications such as diffraction tomography. The reconstruction problem is often formulated as a nonconvex optimization, where a nonlinear measurement model is…
The mathematical problem for Electrical Impedance Tomography (EIT) is a highly nonlinear ill-posed inverse problem requiring carefully designed reconstruction procedures to ensure reliable image generation. D-bar methods are based on a…
Current methods for magnetic resonance-based positron emission tomography attenuation correction (PET-MR AC) are time consuming, and less able than computed tomography (CT)-based AC methods to capture inter-individual variability and skull…
CT images corrupted by metal artifacts have serious negative effects on clinical diagnosis. Considering the difficulty of collecting paired data with ground truth in clinical settings, unsupervised methods for metal artifact reduction are…
Electrical impedance tomography (EIT) is a noninvasive medical imaging modality utilizing the current-density/voltage data measured on the surface of the subject. Calder\'on's method is a relatively recent EIT imaging algorithm that is…
Positron emission tomography (PET) serves as an essential tool for diagnosis of encephalopathy and brain science research. However, it suffers from the limited choice of tracers. Nowadays, with the wide application of PET imaging in…
Phase recovery from intensity-only measurements forms the heart of coherent imaging techniques and holography. Here we demonstrate that a neural network can learn to perform phase recovery and holographic image reconstruction after…
Sparse-view computed tomography (CT) has been adopted as an important technique for speeding up data acquisition and decreasing radiation dose. However, due to the lack of sufficient projection data, the reconstructed CT images often…
To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…
Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) combined with Computed Tomography (CT) scans are critical in oncology to the identification of solid tumours and the monitoring of their progression. However, precise and consistent…
Magnetic resonance imaging (MRI) is increasingly utilized for image-guided radiotherapy due to its outstanding soft-tissue contrast and lack of ionizing radiation. However, geometric distortions caused by gradient nonlinearity (GNL) limit…