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High-dimensional clinical data have become invaluable resources for genetic studies, due to their accessibility in biobank-scale datasets and the development of high performance modeling techniques especially using deep learning. Recent…

Machine Learning · Computer Science 2023-07-19 Taedong Yun

In classification problems, supervised machine-learning methods outperform traditional algorithms, thanks to the ability of neural networks to learn complex patterns. However, in two-class classification tasks like anomaly or fraud…

Machine Learning · Computer Science 2022-04-01 Mihai-Cezar Augustin , Vivien Bonvin , Regis Houssou , Efstratios Rappos , Stephan Robert-Nicoud

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

In this paper, we propose a new approach to deformable image registration that captures sliding motions. The large deformation diffeomorphic metric mapping (LDDMM) registration method faces challenges in representing sliding motion since it…

Optimization and Control · Mathematics 2023-03-15 Lili Bao , Jiahao Lu , Shihui Ying , Stefan Sommer

We propose numerical algorithms for solving large deformation diffeomorphic image registration problems. We formulate the nonrigid image registration problem as a problem of optimal control. This leads to an infinite-dimensional partial…

Numerical Analysis · Mathematics 2015-05-08 Andreas Mang , George Biros

We propose an unsupervised deep learning algorithm for the motion-compensated reconstruction of 5D cardiac MRI data from 3D radial acquisitions. Ungated free-breathing 5D MRI simplifies the scan planning, improves patient comfort, and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Joseph Kettelkamp , Ludovica Romanin , Davide Piccini , Sarv Priya , Mathews Jacob

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

In this paper, we propose a new self-supervised method, which is called Denoising Masked AutoEncoders (DMAE), for learning certified robust classifiers of images. In DMAE, we corrupt each image by adding Gaussian noises to each pixel value…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Quanlin Wu , Hang Ye , Yuntian Gu , Huishuai Zhang , Liwei Wang , Di He

In recent years, learning-based image registration methods have gradually moved away from direct supervision with target warps to instead use self-supervision, with excellent results in several registration benchmarks. These approaches…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Sean I. Young , Yaël Balbastre , Adrian V. Dalca , William M. Wells , Juan Eugenio Iglesias , Bruce Fischl

In this work, we propose to resolve the issue existing in current deep learning based organ segmentation systems that they often produce results that do not capture the overall shape of the target organ and often lack smoothness. Since…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Hui Tang , Zhi Qiao , Guanzhong Gong , Yong Yin , Zhen Qian , Chao Huang , Wei Fan , Xiaolei Huang

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu

We introduce a new predictive mechanism that operates in the presence of hidden confounding across distributionally diverse data sources while ensuring consistent estimation of causal parameters-despite their recognized suboptimality for…

Statistics Theory · Mathematics 2025-04-01 Carlos García Meixide , David Ríos Insua

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based autoencoders have shown great potential in detecting anomalies in medical images. However, especially…

Image and Video Processing · Electrical Eng. & Systems 2020-01-03 David Zimmerer , Simon Kohl , Jens Petersen , Fabian Isensee , Klaus Maier-Hein

Recent advancements in diffusion models have demonstrated significant success in unsupervised anomaly segmentation. For anomaly segmentation, these models are first trained on normal data; then, an anomalous image is noised to an…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Mehrdad Moradi , Kamran Paynabar

Deformable image registration aims to find a dense non-linear spatial correspondence between a pair of images, which is a crucial step for many medical tasks such as tumor growth monitoring and population analysis. Recently, Deep Neural…

Image and Video Processing · Electrical Eng. & Systems 2025-01-09 Mingyuan Meng , Michael Fulham , Dagan Feng , Lei Bi , Jinman Kim

This paper introduces GeoMorph, a novel geometric deep-learning framework designed for image registration of cortical surfaces. The registration process consists of two main steps. First, independent feature extraction is performed on each…

Machine Learning · Computer Science 2023-11-23 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Shearography is a non-destructive testing method for detecting subsurface defects, offering high sensitivity and full-field inspection capabilities. However, its industrial adoption remains limited due to the need for expert interpretation.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Jessica Plassmann , Nicolas Schuler , Georg von Freymann , Michael Schuth

Detecting structures at the particle scale within plastically deformed crystalline materials allows a better understanding of the occurring phenomena. While previous approaches mostly relied on applying hand-chosen criteria on different…

Materials Science · Physics 2024-05-15 Armand Barbot , Riccardo Gatti

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan
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