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The adaptive and surprising emergent properties of biological materials self-assembled in far-from-equilibrium environments serve as an inspiration for efforts to design nanomaterials and their properties. In particular, controlling the…

Statistical Mechanics · Physics 2023-07-07 Shriram Chennakesavalu , Sreekanth K. Manikandan , Frank Hu , Grant M. Rotskoff

The intelligent behavior of robots does not emerge solely from control systems, but from the tight coupling between body and brain, a principle known as embodied intelligence. Designing soft robots that leverage this interaction remains a…

Robotics · Computer Science 2026-03-23 Jianqiang Wang , Shuaiqun Pan , Alvaro Serra-Gomez , Xiaohan Wei , Yue Xie

Many organisms exhibit branching morphologies that twist around each other and become entangled. Entanglement occurs when different objects interlock, creating complex and often irreversible configurations. This physical phenomenon is…

The relation between a structure and the function running on that structure is of central interest in many fields, including computer science, biology (organ vs. function), psychology (body vs. mind), architecture (designs vs.…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-16 Ciprian Ionut Paduraru , Gheorghe Stefanescu

The design of amorphous entangled systems, specifically from soft and active materials, has the potential to open exciting new classes of active, shape-shifting, and task-capable 'smart' materials. However, the global emergent mechanics…

Soft Condensed Matter · Physics 2022-07-11 William Savoie , Harry Tuazon , M. Saad Bhamla , Daniel I. Goldman

An autonomous adaptive MPC architecture is presented for control of heating, ventilation and air condition (HVAC) systems to maintain indoor temperature while reducing energy use. Although equipment use and occupant changes with time,…

Systems and Control · Electrical Eng. & Systems 2021-02-09 Tingting Zeng , Prabir Barooah

Advances in synthetic biology allow us to engineer bacterial collectives with pre-specified characteristics. However, the behavior of these collectives is difficult to understand, as cellular growth and division as well as extra-cellular…

Cell Behavior · Quantitative Biology 2017-09-13 James J. Winkle , Oleg Igoshin , Matthew R. Bennett , Krešimir Josić , William Ott

Biological transport networks are highly optimized structures that ensure power-efficient distribution of fluids across various domains, including animal vasculature and plant venation. Theoretically, these networks can be described as…

Biological Physics · Physics 2025-08-01 Albert Alonso , Lars Erik J. Skjegstad , Julius B. Kirkegaard

The growth of plants is a hydromechanical phenomenon in which cells enlarge by absorbing water, while their walls expand and remodel under turgor-induced tension. In multicellular tissues, where cells are mechanically interconnected,…

Biological Physics · Physics 2025-09-09 Hadrien Oliveri , Ibrahim Cheddadi

Morphoelasticity represents a foundational theory for tracing back growth, remodelling, and morphogenesis, yet crucial challenges persist. A unified growth law -- independent of a priori assumptions about constitutive relations or specified…

Soft Condensed Matter · Physics 2025-07-29 Angelo Rosario Carotenuto , Stefania Palumbo , Arsenio Cutolo , Massimiliano Fraldi

Creating autonomous, self-supporting, self-replicating, sustainable systems is a great challenge. To some extent, understanding life means not only being able to create it from scratch, but also improving, supporting, saving it, or even…

Robotics · Computer Science 2011-11-07 Serge Kernbach

Traditional robotic mechanisms contain a series of rigid links connected by rotational joints that provide powered motion, all of which is controlled by a central processor. By contrast, analogous mechanisms found in nature, such as octopus…

Computational Engineering, Finance, and Science · Computer Science 2023-11-06 Anurag Bhattacharyya , Jin-Young Kim , Lee R. Alacoque , Kai A. James

Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

The remarkable range of biological forms in and around us, such as the undulating shape of a leaf or flower in the garden, the coils in our gut, or the folds in our brain, raise a number of questions at the interface of biology, physics and…

General Mathematics · Mathematics 2021-05-13 Marta Lewicka , L. Mahadevan

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

Many biological materials must couple mechanical strength with the ability to rapidly self-assemble at a specific location. In particular, biomolecular condensates readily self-assemble via phase separation, but may also need to resist…

Interconnectivity, fault tolerance, and dynamic evolution of the circuitry are long sought-after objectives of bio-inspired engineering. Here, we propose dendritic transistors composed of organic semiconductors as building blocks for…

Emerging Technologies · Computer Science 2021-06-14 Matteo Cucchi , Hans Kleemann , Hsin Tseng , Alexander Lee , Karl Leo

We consider a free boundary problem for a system of PDEs, modeling the growth of a biological tissue. A morphogen, controlling volume growth, is produced by specific cells and then diffused and absorbed throughout the domain. The geometric…

Analysis of PDEs · Mathematics 2017-11-22 Alberto Bressan , Marta Lewicka