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The problem of string reconstruction from substring information has found many applications due to its relevance in DNA- and polymer-based data storage. One practically important and challenging paradigm requires reconstructing mixtures of…

Information Theory · Computer Science 2020-10-22 Ryan Gabrys , Srilakshmi Pattabiraman , Olgica Milenkovic

This paper studies reconstruction of strings based upon their substrings spectrum. Under this paradigm, it is assumed that all substrings of some fixed length are received and the goal is to reconstruct the string. While many existing works…

Information Theory · Computer Science 2021-06-02 Sagi Marcovich , Eitan Yaakobi

The problem of reconstructing strings from substring information has found many applications due to its importance in genomic data sequencing and DNA- and polymer-based data storage. One practically important and challenging paradigm…

Information Theory · Computer Science 2021-10-07 Ryan Gabrys , Srilakshmi Pattabiraman , Olgica Milenkovic

The problem of string reconstruction based on its substrings spectrum has received significant attention recently due to its applicability to DNA data storage and sequencing. In contrast to previous works, we consider in this paper a setup…

Information Theory · Computer Science 2022-05-11 Yonatan Yehezkeally , Sagi Marcovich , Eitan Yaakobi

This paper studies the problem of encoding messages into sequences which can be uniquely recovered from some noisy observations about their substrings. The observed reads comprise consecutive substrings with some given minimum overlap. This…

Information Theory · Computer Science 2023-12-11 Hengjia Wei , Moshe Schwartz , Gennian Ge

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2023-04-21 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

We consider the problem of binary string reconstruction from the multiset of its substring compositions, i.e., referred to as the substring composition multiset, first introduced and studied by Acharya et al. We introduce a new algorithm…

Information Theory · Computer Science 2023-06-05 Utkarsh Gupta , Hessam Mahdavifar

Motivated by applications in polymer-based data storage, we study the problem of reconstructing a string from part of its composition multiset. We give a full description of the structure of the strings that cannot be uniquely reconstructed…

Information Theory · Computer Science 2022-10-18 Zuo Ye , Ohad Elishco

Motivated by mass-spectrometry protein sequencing, we consider a simply-stated problem of reconstructing a string from the multiset of its substring compositions. We show that all strings of length 7, one less than a prime, or one less than…

Discrete Mathematics · Computer Science 2014-03-12 Jayadev Acharya , Hirakendu Das , Olgica Milenkovic , Alon Orlitsky , Shengjun Pan

Motivated by studies of data retrieval in polymer-based storage systems, we consider the problem of reconstructing a multiset of binary strings that have the same length and the same weight from the compositions of their prefixes and…

Discrete Mathematics · Computer Science 2024-11-07 Yaoyu Yang , Zitan Chen

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Motivated by polymer-based data-storage platforms that use chains of binary synthetic polymers as the recording media and read the content via tandem mass spectrometers, we propose a new family of codes that allows for unique string…

Information Theory · Computer Science 2019-04-22 Srilakshmi Pattabiraman , Ryan Gabrys , Olgica Milenkovic

The problem called "String reconstruction from substrings" is a mathematical model of sequencing by hybridization that plays an important role in DNA sequencing. In this problem, we are given a blackbox oracle holding an unknown string…

Data Structures and Algorithms · Computer Science 2018-08-03 Kazuo Iwama , Junichi Teruyama , Shuntaro Tsuyama

The sequence reconstruction problem, introduced by Levenshtein in 2001, considers a communication scenario where the sender transmits a codeword from some codebook and the receiver obtains multiple noisy reads of the codeword. The common…

Information Theory · Computer Science 2020-06-16 Kui Cai , Han Mao Kiah , Tuan Thanh Nguyen , Eitan Yaakobi

We consider the problem of coding for the substring channel, in which information strings are observed only through their (multisets of) substrings. Due to existing DNA sequencing techniques and applications in DNA-based storage systems,…

Information Theory · Computer Science 2024-03-27 Yonatan Yehezkeally , Nikita Polyanskii

Motivated by polymer-based data-storage platforms that use chains of binary synthetic polymers as the recording media and read the content via tandem mass spectrometers, we propose a new family of codes that allows for both unique string…

Information Theory · Computer Science 2021-06-29 Srilakshmi Pattabiraman , Ryan Gabrys , Olgica Milenkovic

Reconstruction codes are generalizations of error-correcting codes that can correct errors by a given number of noisy reads. The study of such codes was initiated by Levenshtein in 2001 and developed recently due to applications in modern…

Information Theory · Computer Science 2023-02-21 Zuo Ye , Xin Liu , Xiande Zhang , Gennian Ge

Graphs are a powerful tool for analyzing large data sets, but many real-world phenomena involve interactions that go beyond the simple pairwise relationships captured by a graph. In this paper we introduce and study a simple combinatorial…

Data Structures and Algorithms · Computer Science 2025-11-25 Elise Tate , Joshua A. Grochow

Synthetic polymer-based storage seems to be a particularly promising candidate that could help to cope with the ever-increasing demand for archival storage requirements. It involves designing molecules of distinct masses to represent the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Antonia Wachter-Zeh , Eitan Yaakobi

The problem of reconstructing a sequence from the set of its length-$k$ substrings has received considerable attention due to its various applications in genomics. We study an uncoded version of this problem where multiple random sources…

Information Theory · Computer Science 2023-05-11 Kel Levick , Ilan Shomorony
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