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Predictive marker patterns in imaging data are a means to quantify disease and progression, but their identification is challenging, if the underlying biology is poorly understood. Here, we present a method to identify predictive texture…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Matthias Perkonigg , Daniel Sobotka , Ahmed Ba-Ssalamah , Georg Langs

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Positron Emission Tomography scan images are extensively used in radiotherapy planning, clinical diagnosis, assessment of growth and treatment of a tumor. These all rely on fidelity and speed of detection and delineation algorithm. Despite…

Medical Physics · Physics 2017-10-25 Yeman B. Hagos , Vu H. Minh , Saed Khawaldeh , Usama Pervaiz , Tajwar A. Aleef

We propose a novel unsupervised image segmentation algorithm, which aims to segment an image into several coherent parts. It requires no user input, no supervised learning phase and assumes an unknown number of segments. It achieves this by…

Computer Vision and Pattern Recognition · Computer Science 2016-03-09 Aleksandar Dimitriev , Matej Kristan

The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xinrong Hu , Dewen Zeng , Xiaowei Xu , Yiyu Shi

Automated brain tumor segmentation based on deep learning (DL) has achieved promising performance. However, it generally relies on annotated images for model training, which is not always feasible in clinical settings. Therefore, the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Xinru Zhang , Ni Ou , Chenghao Liu , Zhizheng Zhuo , Yaou Liu , Chuyang Ye

Supervised deep learning-based methods yield accurate results for medical image segmentation. However, they require large labeled datasets for this, and obtaining them is a laborious task that requires clinical expertise.…

Computer Vision and Pattern Recognition · Computer Science 2021-12-20 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

In many applications of X-ray computed tomography, an unsupervised segmentation of the reconstructed 3D volumes forms an important step in the image processing chain for further investigation of the digitized object. Therefore, the goal is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-09 Thomas Lang

Traditional k-means clustering underperforms on non-convex shapes and requires the number of clusters k to be specified in advance. We propose a simple geometric enhancement: after standard k-means, each cluster center is assigned a radius…

Machine Learning · Computer Science 2025-04-30 Stefan Kober

Unsupervised pre-training has been proven as an effective approach to boost various downstream tasks given limited labeled data. Among various methods, contrastive learning learns a discriminative representation by constructing positive and…

Image and Video Processing · Electrical Eng. & Systems 2022-02-17 Jizong Peng , Ping Wang , Marco Pedersoli , Christian Desrosiers

Recently, self-supervised learning (SSL) methods have been used in pre-training the segmentation models for 2D and 3D medical images. Most of these methods are based on reconstruction, contrastive learning and consistency regularization.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Haofeng Li , Yiming Ouyang , Xiang Wan

Semi-supervised learning (SSL) has made notable advancements in medical image segmentation (MIS), particularly in scenarios with limited labeled data and significantly enhancing data utilization efficiency. Previous methods primarily focus…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Mengzhu Wang , Jiao Li , Houcheng Su , Nan Yin , Liang Yang , Shen Li

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Semi-supervised segmentation tackles the scarcity of annotations by leveraging unlabeled data with a small amount of labeled data. A prominent way to utilize the unlabeled data is by consistency training which commonly uses a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 Sukesh Adiga , Jose Dolz , Herve Lombaert

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Jia Dong , Yao Yao , Yang Dong , Hui Ma

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Brain tumor segmentation is important for diagnosis of the tumor, and current deep-learning methods rely on a large set of annotated images for training, with high annotation costs. Unsupervised segmentation is promising to avoid human…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Xiaochuan Ma , Jia Fu , Wenjun Liao , Shichuan Zhang , Guotai Wang