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Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…

Machine Learning · Computer Science 2023-09-07 Bliss Singhal , Fnu Pooja

Epilepsy affects more than 50 million people worldwide, making it one of the world's most prevalent neurological diseases. The main symptom of epilepsy is seizures, which occur abruptly and can cause serious injury or death. The ability to…

Signal Processing · Electrical Eng. & Systems 2024-02-06 Zakary Georgis-Yap , Milos R. Popovic , Shehroz S. Khan

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

Neurons and Cognition · Quantitative Biology 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

Purpose: Research into epileptic networks has recently allowed deeper insights into the epileptic process. Here we investigated the importance of individual network nodes for seizure dynamics. Methods: We analysed intracranial…

Neurons and Cognition · Quantitative Biology 2014-12-03 Christian Geier , Stephan Bialonski , Christian E. Elger , Klaus Lehnertz

We explore the use of neural networks trained with dropout in predicting epileptic seizures from electroencephalographic data (scalp EEG). The input to the neural network is a 126 feature vector containing 9 features for each of the 14 EEG…

Machine Learning · Computer Science 2019-02-05 Siddharth Pramod , Adam Page , Tinoosh Mohsenin , Tim Oates

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

Neurons and Cognition · Quantitative Biology 2022-12-13 Dominic RW Burrows

Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…

Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the…

Adaptation and Self-Organizing Systems · Physics 2018-10-02 Malbor Asllani , Timoteo Carletti

Electroencephalogram (EEG) is a prominent way to measure the brain activity for studying epilepsy, thereby helping in predicting seizures. Seizure prediction is an active research area with many deep learning based approaches dominating the…

Signal Processing · Electrical Eng. & Systems 2020-11-19 Zaid Bin Tariq , Arun Iyengar , Lara Marcuse , Hui Su , Bülent Yener

Identifying seizure activities in non-stationary electroencephalography (EEG) is a challenging task, since it is time-consuming, burdensome, and dependent on expensive human resources and subject to error and bias. A computerized seizure…

Signal Processing · Electrical Eng. & Systems 2020-04-29 S. Sheykhivand , T. Yousefi Rezaii , Z. Mousavi , A. Delpak , A. Farzamnia

An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…

Objective: This work presents a new computational framework to assist neurophysiologists in Stereoelectroencephalography (SEEG) analysis, with the goal of improving the definition of the Epileptogenic Zone (EZ) in patients with…

Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Theekshana Dissanayake , Tharindu Fernando , Simon Denman , Sridha Sridharan , Clinton Fookes

Epilepsy is a brain disorder due to abnormalactivity of neurons and recording of seizures is of primary interest in the evaluation of epileptic patients. A seizureis the phenomenon of rhythmicity discharge from either a local area or the…

Signal Processing · Electrical Eng. & Systems 2019-03-26 Hesam Akbari , Somayeh Saraf Esmaili , Sima Farzollah Zadeh

Over 15 million epilepsy patients worldwide do not respond to drugs and require surgical treatment. Successful surgical treatment requires complete removal, or disconnection of the epileptogenic zone (EZ), but without a prospective…

Machine Learning · Computer Science 2022-02-16 Adam Li , Chester Huynh

While Deep Learning (DL) is often considered the state-of-the art for Artificial Intelligence-based medical decision support, it remains sparsely implemented in clinical practice and poorly trusted by clinicians due to insufficient…

Machine Learning · Computer Science 2020-12-23 Valentin Gabeff , Tomas Teijeiro , Marina Zapater , Leila Cammoun , Sylvain Rheims , Philippe Ryvlin , David Atienza

Epilepsy affects nearly 1% of the global population, of which two thirds can be treated by anti-epileptic drugs and a much lower percentage by surgery. Diagnostic procedures for epilepsy and monitoring are highly specialized and…

Signal Processing · Electrical Eng. & Systems 2020-01-20 Tennison Liu , Nhan Duy Truong , Armin Nikpour , Luping Zhou , Omid Kavehei

There is increasing evidence for specific cortical and subcortical large-scale human epileptic networks to be involved in the generation, spread, and termination of not only primary generalized but also focal onset seizures. The complex…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Marie-Therese Kuhnert , Christian E. Elger , Klaus Lehnertz

Epilepsy is one of the most common neurological disorders that greatly impair patient' daily lives. Traditional epileptic diagnosis relies on tedious visual screening by neurologists from lengthy EEG recording that requires the presence of…

Artificial Intelligence · Computer Science 2016-11-18 Forrest Sheng Bao , Donald Yu-Chun Lie , Yuanlin Zhang