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The ability of the adaptive immune system to discriminate between self and non-self mainly stems from the ontogenic clonal-deletion of lymphocytes expressing strong binding affinity with self-peptides. However, some self-directed…

Biological Physics · Physics 2012-12-12 Elena Agliari , Adriano Barra , Gino Del Ferraro , Francesco Guerra , Daniele Tantari

One basic requirement of many studies is the necessity of classifying data. Clustering is a proposed method for summarizing networks. Clustering methods can be divided into two categories named model-based approaches and algorithmic…

Machine Learning · Computer Science 2013-02-19 Raheleh Namayandeh , Farzad Didehvar , Zahra Shojaei

Malware attacks have become significantly more frequent and sophisticated in recent years. Therefore, malware detection and classification are critical components of information security. Due to the large amount of malware samples…

Cryptography and Security · Computer Science 2024-05-07 Olha Jurečková , Martin Jureček , Mark Stamp

Generative approaches to clustering provide information on geometric properties of clusters, whereas discriminative approaches provide boundaries between clusters. Ideas from both approaches are incorporated to present a fully unsupervised,…

Machine Learning · Statistics 2026-04-28 Mackenzie R. Neal , Paul D. McNicholas , Arthur White

Kernel-based clustering algorithms have the ability to capture the non-linear structure in real world data. Among various kernel-based clustering algorithms, kernel k-means has gained popularity due to its simple iterative nature and ease…

Computer Vision and Pattern Recognition · Computer Science 2014-02-18 Radha Chitta , Rong Jin , Timothy C. Havens , Anil K. Jain

Clustering is a usual unsupervised machine learning technique for grouping the data points into groups based upon similar features. We focus here on unsupervised clustering for contaminated data, i.e in the case where K-medians should be…

Statistics Theory · Mathematics 2024-02-28 Antoine Godichon-Baggioni , Sobihan Surendran

Clustering algorithms are fundamental tools across many fields, with density-based methods offering particular advantages in identifying arbitrarily shaped clusters and handling noise. However, their effectiveness is often limited by the…

Machine Learning · Computer Science 2025-12-01 Meysam Shirdel Bilehsavar , Razieh Ghaedi , Samira Seyed Taheri , Xinqi Fan , Christian O'Reilly

Estimating heterogeneous treatment effects is critical in domains such as personalized medicine, resource allocation, and policy evaluation. A central challenge lies in identifying subpopulations that respond differently to interventions,…

Machine Learning · Statistics 2025-09-18 Zilong Wang , Turgay Ayer , Shihao Yang

When a data set has significant differences in its class and cluster structure, selecting features aiming only at the discrimination of classes would lead to poor clustering performance, and similarly, feature selection aiming only at…

Machine Learning · Computer Science 2023-07-11 Suchismita Das , Nikhil R. Pal

Artificial Immune Systems have been used successfully to build recommender systems for film databases. In this research, an attempt is made to extend this idea to web site recommendation. A collection of more than 1000 individuals web…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Tom Morrison , Uwe Aickelin

Consider unsupervised clustering of objects drawn from a discrete set, through the use of human intelligence available in crowdsourcing platforms. This paper defines and studies the problem of universal clustering using responses of crowd…

Human-Computer Interaction · Computer Science 2016-10-11 Ravi Kiran Raman , Lav Varshney

Similarity-based clustering methods separate data into clusters according to the pairwise similarity between the data, and the pairwise similarity is crucial for their performance. In this paper, we propose {\em Clustering by Discriminative…

Machine Learning · Computer Science 2022-06-24 Yingzhen Yang , Ping Li

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

Computation · Statistics 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

A novel nonparametric clustering algorithm is proposed using the interpoint distances between the members of the data to reveal the inherent clustering structure existing in the given set of data, where we apply the classical nonparametric…

Methodology · Statistics 2024-09-02 Soumita Modak

Existing clustering methods for functional data often prioritize partitioning accuracy over interpretability, making it challenging to extract meaningful insights when the data-generating process follows a specific underlying structure and…

The role of T-cells within the immune system is to confirm and assess anomalous situations and then either respond to or tolerate the source of the effect. To illustrate how these mechanisms can be harnessed to solve real-world problems, we…

Artificial Intelligence · Computer Science 2010-07-05 Jungwon Kim , William Wilson , Uwe Aickelin , Julie McLeod

Term clustering is important in biomedical knowledge graph construction. Using similarities between terms embedding is helpful for term clustering. State-of-the-art term embeddings leverage pretrained language models to encode terms, and…

Computation and Language · Computer Science 2022-04-04 Sihang Zeng , Zheng Yuan , Sheng Yu

Contrastive learning is an efficient approach to self-supervised representation learning. Although recent studies have made progress in the theoretical understanding of contrastive learning, the investigation of how to characterize the…

Machine Learning · Computer Science 2023-08-21 Hiroki Waida , Yuichiro Wada , Léo Andéol , Takumi Nakagawa , Yuhui Zhang , Takafumi Kanamori

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

Cluster-based algorithm selection deals with selecting recommendation algorithms on clusters of users to obtain performance gains. No studies have been attempted for many combinations of clustering approaches and recommendation algorithms.…

Information Retrieval · Computer Science 2024-05-29 Andreas Lizenberger , Ferdinand Pfeifer , Bastian Polewka
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