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We consider the bi-criteria shortest-path problem where we want to compute shortest paths on a graph that simultaneously balance two cost functions. While this problem has numerous applications, there is usually no path minimizing both cost…

Data Structures and Algorithms · Computer Science 2021-03-08 Oren Salzman

Current hardware limitations restrict the potential when solving quadratic unconstrained binary optimization (QUBO) problems via the quantum approximate optimization algorithm (QAOA) or quantum annealing (QA). Thus, we consider training…

Quantum Physics · Physics 2020-04-30 Thomas Gabor , Sebastian Feld , Hila Safi , Thomy Phan , Claudia Linnhoff-Popien

Nervous systems, like any organismal structure, have been shaped by evolutionary processes to increase fitness. The resulting neural 'bauplan' has to account for multiple objectives simultaneously, including computational function as well…

Neurons and Cognition · Quantitative Biology 2021-05-05 Fabian Pallasdies , Philipp Norton , Jan-Hendrik Schleimer , Susanne Schreiber

Bilevel optimization problems comprise an upper level optimization task that contains a lower level optimization task as a constraint. While there is a significant and growing literature devoted to solving bilevel problems with single…

Neural and Evolutionary Computing · Computer Science 2024-09-06 Bing Wang , Hemant K. Singh , Tapabrata Ray

This work addresses a Multi-Objective Shortest Path Problem (MO-SPP) on a graph where the goal is to find a set of Pareto-optimal solutions from a start node to a destination in the graph. A family of approaches based on MOA* have been…

Artificial Intelligence · Computer Science 2022-05-31 Zhongqiang Ren , Richard Zhan , Sivakumar Rathinam , Maxim Likhachev , Howie Choset

Multi-objective optimization (MOO) is a prevalent challenge for Deep Learning, however, there exists no scalable MOO solution for truly deep neural networks. Prior work either demand optimizing a new network for every point on the Pareto…

Machine Learning · Computer Science 2021-10-15 Michael Ruchte , Josif Grabocka

The Quantum Approximate Optimization Algorithm (QAOA) requires considered optimization problems to be translated into a compatible format. A popular transformation step in this pipeline involves the quadratization of higher-order binary…

Quantum Physics · Physics 2025-11-26 Damian Rovara , Lukas Burgholzer , Robert Wille

We explore the application of variational quantum algorithms to the NP-hard set balancing problem, a critical challenge in clinical trial design and experimental scheduling. The problem is mapped to an Ising model, with tailored Quadratic…

Quantum Physics · Physics 2025-09-10 Nikhil Kowshik , Sayan Manna , Sudebkumar Prasant Pal

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

Multiobjective combinatorial optimization (MOCO) problems can be found in many real-world applications. However, exactly solving these problems would be very challenging, particularly when they are NP-hard. Many handcrafted heuristic…

Machine Learning · Computer Science 2022-05-10 Xi Lin , Zhiyuan Yang , Qingfu Zhang

We model the formation of multi-layer transportation networks as a multi-objective optimization process, where service providers compete for passengers, and the creation of routes is determined by a multi-objective cost function encoding a…

Physics and Society · Physics 2018-09-26 Andrea Santoro , Vito Latora , Giuseppe Nicosia , Vincenzo Nicosia

In the pursuit of achieving near-term quantum advantage for combinatorial optimization problems, the Quantum Approximate Optimization Algorithm (QAOA) and the Variational Quantum Eigensolver (VQE) are the primary methods of interest, but…

Quantum Physics · Physics 2025-03-06 Adelina Bärligea , Benedikt Poggel , Jeanette Miriam Lorenz

For a practical quantum key distribution (QKD) system, parameter optimization - the choice of intensities and probabilities of sending them - is a crucial step in gaining optimal performance, especially when one realistically considers…

Quantum Physics · Physics 2020-01-01 Wenyuan Wang , Hoi-Kwong Lo

Current computer-aided synthesis planning (CASP) methods often treat retrosynthesis as solved once a single feasible route is identified, focusing primarily on convergence or shortest-path metrics. This view is misaligned with real-world…

Artificial Intelligence · Computer Science 2026-05-27 Friedrich Hastedt , Dongda Zhang , Antonio del Rio Chanona

Recent studies suggest that gradient-based methods applied to relaxed box-constrained Quadratic Unconstrained Binary Optimization (QUBO) formulations can outperform classical heuristics in some large-scale regimes, often relying on heavy…

Discrete Mathematics · Computer Science 2026-05-11 Yongliang Sun , Ismail Alkhouri , Cheng-Han Huang , Alvaro Velasquez , Susmit Jha , Rongrong Wang

Ant colony optimization (ACO) is a commonly used meta-heuristic to solve complex combinatorial optimization problems like traveling salesman problem (TSP), vehicle routing problem (VRP), etc. However, classical ACO algorithms provide better…

Emerging Technologies · Computer Science 2021-11-05 Mrityunjay Ghosh , Nivedita Dey , Debdeep Mitra , Amlan Chakrabarti

Quantum Key Distribution (QKD) networks harness the principles of quantum physics in order to securely transmit cryptographic key material, providing physical guarantees. These networks require traditional management and operational…

Networking and Internet Architecture · Computer Science 2026-01-28 Jorge López , Charalampos Chatzinakis , Marc Cartigny

This paper presents a quantum-based Fourier-regression approach for machine learning hyperparameter optimization applied to a benchmark of models trained on a dataset related to a forecast problem in the airline industry. Our approach…

Quantum networks rely on high-fidelity entanglement links, but achieving target fidelity often increases latency and Bell pair consumption due to purification. This paper proposes a cost-based scheduler that jointly optimizes path selection…

Quantum Physics · Physics 2026-03-04 Gongyu Ni , Holger Claussen , Lester Ho

Pareto-optimality plays a central role in evaluating the efficiency of solutions to allocation problems, such as house allocation, school choice, and kidney exchange. We introduce a general linear programming problem subject to…

Optimization and Control · Mathematics 2025-09-23 Bart van Rossum , Twan Dollevoet