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Shape transformations of epithelial tissues in three dimensions, which are crucial for embryonic development or in vitro organoid growth, can result from active forces generated within the cytoskeleton of the epithelial cells. How the…

Biological Physics · Physics 2024-12-23 Diana Khoromskaia , Guillaume Salbreux

Topological invariants have proved useful for analyzing emergent function as they characterize a property of the entire system, and are insensitive to local details, disorder, and noise. They support boundary states, which reduce the system…

Statistical Mechanics · Physics 2025-10-10 Jaime Agudo-Canalejo , Evelyn Tang

The onset of stochasticity is measured in $\Lambda$CDM cosmological simulations using a set of classical observables. It is quantified as the local derivative of the logarithm of the dispersion of a given observable (within a set of…

Astrophysics · Physics 2009-11-13 Jerome Thiebaut , Christophe Pichon , Thierry Sousbie , Simon Prunet , D. Pogosyan

Fractional killing in response to drugs is a hallmark of non-genetic cellular heterogeneity. Yet how individual lineages evade drug treatment, as observed in bacteria and cancer cells, is not quantitatively understood. We analyse a…

Populations and Evolution · Quantitative Biology 2024-09-25 Francesco Puccioni , Johannes Pausch , Paul Piho , Philipp Thomas

Phenotypic noise underpins homeostasis and fitness of individual cells. Yet, the extent to which noise shapes cell-to-population properties in microbial active matter remains poorly understood. By quantifying variability in confluent…

Biological Physics · Physics 2023-11-07 Jayabrata Dhar , Anh L. P. Thai , Arkajyoti Ghoshal , Luca Giomi , Anupam Sengupta

In most vertebrate species, the body axis is generated by the formation of repeated transient structures called somites. This spatial periodicity in somitogenesis has been related to the temporally sustained oscillations in certain mRNAs…

Quantitative Methods · Quantitative Biology 2009-11-13 K. I. Mazzitello , C. M. Arizmendi , H. G. E. Hentschel

Fast scrambling, quantified by the exponential initial growth of Out-of-Time-Ordered-Correlators (OTOCs), is the ability to efficiently spread quantum correlations among the degrees of freedom of interacting systems, and constitutes a…

Quantum Physics · Physics 2023-05-04 Felix Meier , Mathias Steinhuber , Juan Diego Urbina , Daniel Waltner , Thomas Guhr

Our current understanding of brain rhythms is based on quantifying their instantaneous or time-averaged characteristics. What remains unexplored, is the actual structure of the waves -- their shapes and patterns over finite timescales. To…

Neurons and Cognition · Quantitative Biology 2022-05-10 Clarissa Hoffman , Jingheng Cheng , Daoyun Ji , Y. Dabaghian

Stochastic growth processes give rise to diverse intricate structures everywhere and across all scales in nature. Despite the seemingly unrelated complex phenomena at their origin, the Laplacian growth theory has succeeded in unifying their…

Statistical Mechanics · Physics 2016-05-31 J. R. Nicolás-Carlock , J. L. Carrillo-Estrada , V. Dossetti

We present a study investigating the role of mitochondrial variability in generating noise in eukaryotic cells. Noise in cellular physiology plays an important role in many fundamental cellular processes, including transcription,…

Cell Behavior · Quantitative Biology 2015-05-28 Iain G. Johnston , Bernadett Gaal , Ricardo Pires das Neves , Tariq Enver , Francisco J. Iborra , Nick S. Jones

Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this variability on buckling are unknown.…

Soft Condensed Matter · Physics 2025-12-12 Rahul G. Ramachandran , Ricard Alert , Pierre A. Haas

Environmental stochasticity is known to be a destabilizing factor, increasing abundance fluctuations and extinction rates of populations. However, the stability of a community may benefit from the differential response of species to…

Populations and Evolution · Quantitative Biology 2016-02-10 Matan Danino , Nadav M. Shnerb , Sandro Azaele , William E. Kunin , David A. Kessler

In early development, regulation of transcription results in precisely positioned and highly reproducible expression patterns that specify cellular identities. How transcription, a fundamentally noisy molecular process, is regulated to…

Subcellular Processes · Quantitative Biology 2018-01-10 Benjamin Zoller , Shawn C. Little , Thomas Gregor

Natural bacterial habitats are often complex fluids with viscoelastic and anisotropic responses to stress; for example, they can take the form of liquid crystals (LCs), with elongated microscopic constituents that collectively align while…

We present a study of disorder origination and growth inside an ordered phase processes induced by the presence of multiplicative noise within mean-field approximation. Our research is based on the study of solutions of the nonlinear…

Pattern Formation and Solitons · Physics 2017-03-14 S. E. Kurushina , E. A. Shapovalova

Multifractal analysis of stochastic processes deals with the fine scale properties of the sample paths and seeks for some global scaling property that would enable extracting the so-called spectrum of singularities. In this paper we…

Probability · Mathematics 2014-06-12 Danijel Grahovac , Nikolai N. Leonenko

Understanding the principles that govern dynamical systems is a central challenge across many scientific domains, including biology and ecology. Incomplete knowledge of nonlinear interactions and stochastic effects often renders bottom-up…

Machine Learning · Computer Science 2025-11-18 Gianluigi Pillonetto , Alberto Giaretta , Mauro Bisiacco

The co-evolution of structure and dynamics, known as adaptivity, is a fundamental property in various systems and drives diverse emergent behaviors. However, the adaptivity in previous works is primarily stemmed from pairwise situations,…

Physics and Society · Physics 2025-08-22 Longzhao Liu , Hongwei Zheng , Zhihao Han , Xin Wang , Shaoting Tang

During the development of an organism, cells must coordinate and organize to generate the correct shape, structure, and spatial patterns of tissues and organs, a process known as morphogenesis. The morphogenesis of embryonic tissues is…

Tissues and Organs · Quantitative Biology 2026-04-28 Adrian Aguirre-Tamaral , Elisa Floris , Bernat Corominas-Murtra

Many living and non-living complex systems can be modeled and understood as collective systems made of heterogeneous components that self-organize and generate nontrivial morphological structures and behaviors. This chapter presents a brief…

Adaptation and Self-Organizing Systems · Physics 2018-01-09 Hiroki Sayama