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We propose a robust inferential procedure for assessing uncertainties of parameter estimation in high-dimensional linear models, where the dimension $p$ can grow exponentially fast with the sample size $n$. Our method combines the…

Machine Learning · Statistics 2015-03-19 Tianqi Zhao , Mladen Kolar , Han Liu

Background: The hazard ratio of the Cox proportional hazards model is widely used in randomized controlled trials to assess treatment effects. However, two properties of the hazard ratio including the non-collapsibility and built-in…

Methodology · Statistics 2024-01-17 Helen Bian , Menglan Pang , Guanbo Wang , Zihang Lu

In this article we estimate confidence regions of the common measures of (baseline, treatment effect) in observational studies, where the measure of baseline is baseline risk or baseline odds while the measure of treatment effect is odds…

Computation · Statistics 2015-01-22 Li Yin , Xiaoqin Wang

In a prospective cohort study, examining all participants for incidence of the condition of interest may be prohibitively expensive. For example, the "gold standard" for diagnosing temporomandibular disorder (TMD) is a physical examination…

Methodology · Statistics 2015-07-08 Naomi Brownstein , Jianwen Cai , Gary Slade , Eric Bair

We consider the smoothed maximum likelihood estimator and the smoothed Grenander-type estimator for a monotone baseline hazard rate $\lambda_0$ in the Cox model. We analyze their asymptotic behavior and show that they are asymptotically…

Statistics Theory · Mathematics 2018-05-18 Hendrik P. Lopuhaä , Eni Musta

We propose a class of transformation hazard models for right-censored failure time data. It includes the proportional hazards model (Cox) and the additive hazards model (Lin and Ying) as special cases. Due to the requirement of a…

Statistics Theory · Mathematics 2007-06-13 Gousheng Yin , Joseph G. Ibrahim

Let $\mu$ be a Gaussian measure (say, on ${\bf R}^n$) and let $K, L \subset {\bf R}^n$ be such that K is convex, $L$ is a "layer" (i.e. $L = \{x : a \leq < x,u > \leq b \}$ for some $a$, $b \in {\bf R}$ and $u \in {\bf R}^n$) and the…

Functional Analysis · Mathematics 2009-09-25 Stanislaw J. Szarek , Elisabeth Werner

Previous studies have shown that hazard ratios between treatment groups estimated with the Cox model are uninterpretable because the unspecified baseline hazard of the model fails to identify temporal change in the risk set composition due…

Machine Learning · Statistics 2025-09-04 Takashi Hayakawa , Satoshi Asai

This paper deals with the proportional hazards model proposed by D. R. Cox in a high-dimensional and sparse setting for a regression parameter. To estimate the regression parameter, the Dantzig selector is applied. The variable selection…

Statistics Theory · Mathematics 2017-10-31 Kou Fujimori

Frequentist model averaging has been proposed as a method for incorporating "model uncertainty" into confidence interval construction. Such proposals have been of particular interest in the environmental and ecological statistics…

Methodology · Statistics 2018-05-18 Paul Kabaila

This paper is concerned with inference about low-dimensional components of a high-dimensional parameter vector $\beta^0$ which is identified through instrumental variables. We allow for eigenvalues of the expected outer product of included…

Econometrics · Economics 2020-08-05 Christoph Breunig , Enno Mammen , Anna Simoni

We propose confidence regions with asymptotically correct uniform coverage probability of parameters whose Fisher information matrix can be singular at important points of the parameter set. Our work is motivated by the need for reliable…

Statistics Theory · Mathematics 2022-09-13 Karl Oskar Ekvall , Matteo Bottai

We present a distribution optimization framework that significantly improves confidence bounds for various risk measures compared to previous methods. Our framework encompasses popular risk measures such as the entropic risk measure,…

Machine Learning · Computer Science 2023-06-13 Hao Liang , Zhi-quan Luo

Frailty models are often the model of choice for heterogeneous survival data. A frailty model contains both random effects and fixed effects, with the random effects accommodating for the correlation in the data. Different estimation…

Methodology · Statistics 2019-09-17 Oodally Ajmal , Luc Duchateau , Estelle Kuhn

We explore a novel methodology for constructing confidence regions for parameters of linear models, using predictions from any arbitrary predictor. Our framework requires minimal assumptions on the noise and can be extended to functions…

Machine Learning · Statistics 2024-01-30 Charles Guille-Escuret , Eugene Ndiaye

We study high-dimensional linear models with error-in-variables. Such models are motivated by various applications in econometrics, finance and genetics. These models are challenging because of the need to account for measurement errors to…

Statistics Theory · Mathematics 2017-03-03 Alexandre Belloni , Victor Chernozhukov , Abhishek Kaul

In this paper, we propose a new framework to construct confidence sets for a $d$-dimensional unknown sparse parameter $\theta$ under the normal mean model $X\sim N(\theta,\sigma^2I)$. A key feature of the proposed confidence set is its…

Statistics Theory · Mathematics 2020-08-19 Yang Ning , Guang Cheng

Precision matrices play important roles in many practical applications. Motivated by temporally dependent multivariate data in modern social and scientific studies, we consider the statistical inference of precision matrices for…

Methodology · Statistics 2018-12-21 Jinyuan Chang , Yumou Qiu , Qiwei Yao , Tao Zou

We consider the problem of estimating an unknown $\theta\in {\mathbb{R}}^n$ from noisy observations under the constraint that $\theta$ belongs to certain convex polyhedral cones in ${\mathbb{R}}^n$. Under this setting, we prove bounds for…

Statistics Theory · Mathematics 2015-07-31 Sabyasachi Chatterjee , Adityanand Guntuboyina , Bodhisattva Sen

Measurement error in the covariate of main interest (e.g. the exposure variable, or the risk factor) is common in epidemiologic and health studies. It can effect the relative risk estimator or other types of coefficients derived from the…

Methodology · Statistics 2022-07-20 Sarit Agami