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We consider a spatially extended mesoscopic FitzHugh-Nagumo model with strong local interactions and prove that its asymptotic limit converges towards the classical nonlocal reaction-diffusion FitzHugh-Nagumo system. As the local…

Analysis of PDEs · Mathematics 2022-08-31 Alain Blaustein , Francis Filbet

This paper is devoted to the numerical approximation of the spatially-extended FitzHugh-Nagumo transport equation with strong local interactions based on a particle method. In this regime, the time step can be subject to stability…

Numerical Analysis · Mathematics 2020-09-30 Joachim Crevat , Francis Filbet

We consider a spatially extended mean-field model of a FitzHugh-Nagumo neural network, with a rescaled interaction kernel. Our main purpose is to prove that its asymptotic limit in the regime of strong local interactions converges toward a…

Analysis of PDEs · Mathematics 2020-03-17 Joachim Crevat

A detailed description and validation of a recently developed integration scheme is here reported for one- and two-dimensional reaction-diffusion models. As paradigmatic examples of this class of partial differential equations the complex…

Statistical Mechanics · Physics 2015-06-25 M. Nitti , A. Torcini , S. Ruffo

This article aims to provide insights into the qualitative analysis of some nonlinear Reaction-Diffusion (RD) systems arising in Neuroscience. We first introduce a non-homogeneous FitzHugh-Nagumo (nhFHN) featuring excitability and…

Dynamical Systems · Mathematics 2023-04-05 Benjamin Ambrosio

First time in six decades, uncountable infinite exact solutions of FitzHugh-Nagumo model with diffusion have been found. FitzHugh-Nagumo model is a nonlinear dynamical system applicable to neurosciences, chemical kinetics, cell division,…

Dynamical Systems · Mathematics 2024-07-24 Shahid Sultan Ali Ramji , Eddy Kwessi , Mujahid Abbas

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Pattern Formation and Solitons · Physics 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

In the bistable regime of the FitzHugh-Nagumo model of reaction-diffusion systems, spatially homogeneous patterns may be nonlinearly unstable to the formation of compact ``localized states." The formation of space-filling patterns from…

Condensed Matter · Physics 2009-10-28 Raymond E. Goldstein , David J. Muraki , Dean M. Petrich

In this paper, the transport phenomena of synaptic electric impulses are considered. The FitzHugh--Nagumo and FitzHugh--Rinzel models appear mathematically appropriate for evaluating these scientific issues. Moreover, applications of such…

Mathematical Physics · Physics 2023-06-13 Monica De Angelis

We investigate diffusion-driven instabilities in a FitzHugh-Nagumo reaction-diffusion system with superdiffusive transport, modeled by fractional Laplacian operators with different diffusion orders for the activator and the inhibitor. A…

Pattern Formation and Solitons · Physics 2026-03-04 Rossella Rizzo , Gaetana Gambino , Vincenzo Sciacca , Marco Sammartino

We show how to obtain general nonlinear aggregation-diffusion models, including Keller-Segel type models with nonlinear diffusions, as relaxations from nonlocal compressible Euler-type hydrodynamic systems via the relative entropy method.…

Analysis of PDEs · Mathematics 2019-10-29 José A. Carrillo , Yingping Peng , Aneta Wróblewska-Kamińska

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

Neurons and Cognition · Quantitative Biology 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

In this paper, we quantify the asymptotic limit of collective behavior kinetic equations arising in mathematical biology modeled by Vlasov-type equations with nonlocal interaction forces and alignment. More precisely, we investigate the…

Analysis of PDEs · Mathematics 2020-07-10 José A. Carrillo , Young-Pil Choi , Jinwook Jung

In this article, we discuss the dynamics of the 3-dimensional FitzHugh-Rinzel (FHR) model and a class of non-homogeneous FitzHugh-Nagumo (Nh-FHN) Reaction-Diffusion systems. The Nh-FHN models can be used to generate relevant wave…

Pattern Formation and Solitons · Physics 2022-05-10 B. Ambrosio , M. A. Aziz-Alaoui , Argha Mondal , Arnab Mondal , Sanjeev K. Sharma , Ranjit K. Upadhyay

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

Analysis of PDEs · Mathematics 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

The initial value problem P0, in all of the space, for the spatio - temporal FitzHugh - Nagumo equations is analyzed. When the reaction kinetics of the model can be outlined by means of piecewise linear approximations, then the solution of…

Neurons and Cognition · Quantitative Biology 2012-02-28 M. De Angelis , P. Renno

We give a new proof of the large deviation principle from the hydrodynamic limit for the Ginzberg-Landau model studied in Donsker and Varadhan (1989) using techniques from the theory of stochastic control and weak convergence methods. The…

Probability · Mathematics 2018-03-28 Sayan Banerjee , Amarjit Budhiraja , Michael Perlmutter

An asymptotic equation of motion for the pattern interface in the domain-forming reaction-diffusion systems is derived. The free boundary problem is reduced to the universal equation of non-local contour dynamics in two dimensions in the…

patt-sol · Physics 2009-10-30 C. B. Muratov

In this paper, we are interested in the dynamics of charged particles interacting with the incompressible viscous flow. More precisely, we consider the Vlasov-Poisson or Vlasov-Poisson-Fokker-Planck equation coupled with the incompressible…

Analysis of PDEs · Mathematics 2021-01-05 Young-Pil Choi , Jinwook Jung

The use of high-frequency currents in neurostimulation has received increased attention in recent years due to its varied effects on tissues and cells. Nonlinear differential equations are commonly used as models for Neurons, and averaging…

Analysis of PDEs · Mathematics 2025-12-29 Eduardo Cerpa , Matías Courdurier , Esteban Hernández , Leonel E. Medina , Esteban Paduro
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