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Mechanical characteristics of single biological cells are used to identify and possibly leverage interesting differences among cells or cell populations. Fluidity---hysteresivity normalized to the extremes of an elastic solid or a viscous…

Cell Behavior · Quantitative Biology 2013-10-22 John M. Maloney , Eric Lehnhardt , Alexandra F. Long , Krystyn J. Van Vliet

The morphological dynamics, instabilities and transitions of elastic filaments in viscous flows underlie a wealth of biophysical processes from flagellar propulsion to intracellular streaming, and are also key to deciphering the rheological…

Fluid Dynamics · Physics 2018-11-09 Yanan Liu , Brato Chakrabarti , David Saintillan , Anke Lindner , Olivia du Roure

Brain tissue accommodates non-linear deformations and exhibits time-dependent mechanical behaviour. The latter is one of the most pronounced features of brain tissue, manifesting itself primarily through viscoelastic effects such as stress…

Soft Condensed Matter · Physics 2025-12-23 G. Small , F. Ballatore , C. Giverso , V. Balbi

In the manufacturing process of high-performance particulate materials, viscous sintering plays a crucial role, particularly in fields such as polymer processing and additive manufacturing. The interactions between microscopic particles,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-06 Xiaoxu Dai , Bo Qian , Arkadz Kirshtein , Qingcheng Yang

In the fiber melt spinning of semi-crystalline polymers, the degree of crystallization can be non-homogeneous over the cross-section of the fiber, affecting the properties of the end product. For simulation-based process design, the…

Fluid Dynamics · Physics 2024-07-12 Manuel Ettmüller , Walter Arne , Nicole Marheineke , Raimund Wegener

Objective: This paper presents a force control scheme for brief isotonic holds in an isometrically contracted muscle tissue, with minimal overshoot and settling time to measure its shortening velocity, a key parameter of muscle function.…

Systems and Control · Electrical Eng. & Systems 2022-07-29 Amanda Bianco , Raphael Zonis , Anne-Marie Lauzon , James Richard Forbes , Gijs Ijpma

We show that a viscoelastic thin sheet driven out of equilibrium by active structural remodelling develops a rich variety of shapes as a result of a competition between viscous relaxation and activity. In the regime where active processes…

Soft Condensed Matter · Physics 2020-02-26 D. A. Matoz-Fernandez , Fordyce A. Davidson , Nicola R. Stanley-Wall , Rastko Sknepnek

In this paper we present a theoretical and experimental study aimed at characterizing the hysteretic properties of viscoelastic materials. In the last decades viscoelastic materials have become a reference for new technological…

Instrumentation and Detectors · Physics 2021-10-27 Elena Pierro , Giuseppe Carbone

The viscoelastic properties of arterial tissue dictate vessel behavior in certain disease states, injury modalities, and during some endovascular procedures. In this study, we characterized the viscoelastic mechanical response of porcine…

There has been increasing experimental evidence of non-affine elastic deformation mechanisms in biological soft tissues. These observations call for novel constitutive models which are able to describe the dominant underlying…

Computational Physics · Physics 2021-03-04 Sebastian Skatulla , Carlo Sansour , Georges Limbert

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

The conformational change of biological macromolecule is investigated from the point of quantum transition. A quantum theory on protein folding is proposed. Compared with other dynamical variables such as mobile electrons, chemical bonds…

Biomolecules · Quantitative Biology 2013-08-06 LiaoFu Luo

We carry out a theoretical study of the vibrational and relaxation properties of naturally-occurring proteins with the purpose of characterizing both the folding and equilibrium thermodynamics. By means of a suitable model we provide a full…

Statistical Mechanics · Physics 2007-05-23 Cristian Micheletti , Gianluca Lattanzi , Amos Maritan

Soft materials often exhibit a distinctive power-law viscoelastic response arising from broad distribution of time-scales present in their complex internal structure. A promising tool to accurately describe the rheological behaviour of soft…

Soft Condensed Matter · Physics 2020-07-17 Alessandra Bonfanti , Jonathan Louis Kaplan , Guillaume Charras , Alexandre J Kabla

Biological tissues exhibit diverse mechanical and rheological behaviors during morphogenesis. While much is known about tissue phase transitions controlled by structural order and cell mechanics, key questions regarding how tissue-scale…

Soft Condensed Matter · Physics 2026-04-29 Pengyu Yu , Fridtjof Brauns , M. Cristina Marchetti

Constitutive models that describe the mechanical behavior of soft tissues have advanced greatly over the past few decades. These expert models are generalizable and require the calibration of a number of parameters to fit experimental data.…

Quantitative Methods · Quantitative Biology 2021-07-13 Vahidullah Tac , Vivek D. Sree , Manuel K. Rausch , Adrian B. Tepole

We derive an asymptotically consistent morphoelastic shell model to describe the finite deformations of biological tissues using the variational asymptotical method. Biological materials may exhibit remarkable compressibility when under…

Soft Condensed Matter · Physics 2024-07-23 Xiang Yu , Xiaoyi Chen

We propose a new approach allowing visio-haptic interaction with a FE model of a human liver having both non-linear geometric and material properties. The material properties used in the model are extracted from the experimental data of pig…

Graphics · Computer Science 2021-04-12 Igor Peterlik , Mert Sedef , Cagatay Basdogan , Ludek Matyska

We study two closely related, nonlinear models of a viscoplastic solid. These models capture essential features of plasticity over a wide range of strain rates and applied stresses. They exhibit inelastic strain relaxation and steady flow…

Materials Science · Physics 2009-10-31 Alexander E. Lobkovsky , J. S. Langer

Phase separation is a fundamental phenomenon that produces spatially heterogeneous patterns in soft matter. In this Lecture Note we show that phase separation in these materials generally belongs to what we call "viscoelastic phase…

Soft Condensed Matter · Physics 2013-07-08 Hajime Tanaka