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This article presents an Analysis of Variance model for functional data that explicitly incorporates phase variability through a time-warping component, allowing for a unified approach to estimation and inference in presence of amplitude…

Methodology · Statistics 2013-11-11 Daniel Gervini , Patrick A. Carter

In genomic applications, there is often interest in identifying genes whose time-course expression trajectories exhibit periodic oscillations with a period of approximately 24 hours. Such genes are usually referred to as circadian, and…

Methodology · Statistics 2024-02-28 Silvia Montagna , Irina Irincheeva , Surya T. Tokdar

Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This…

Machine Learning · Statistics 2017-11-29 Disi Ji , Eric Nalisnick , Padhraic Smyth

It is well-known that adaptive homodyne estimation of continuously varying optical phase provides superior accuracy in the phase estimate as compared to adaptive or non-adaptive static estimation. However, most phase estimation schemes rely…

Optimization and Control · Mathematics 2015-09-14 Shibdas Roy , Ian R. Petersen , Elanor H. Huntington

We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to…

Machine Learning · Computer Science 2015-04-24 Dong Mao , Yang Wang , Qiang Wu

Quasi-static aberrations in coronagraphic systems are the ultimate limitation to the capabilities of exoplanet imagers both ground-based and space-based. These aberrations - which can be due to various causes such as optics alignment or…

Instrumentation and Methods for Astrophysics · Physics 2019-07-31 Olivier Herscovici-Schiller , Jean-François Sauvage , Laurent M. Mugnier , Kjetil Dohlen , Arthur Vigan

Whisking is a rhythmic and adaptive behavior that rodents use to probe and interact with their environment, and the frequency of movement reflects both sensorimotor processing and internal brain states. A robust and traditional method of…

Quantitative Methods · Quantitative Biology 2026-05-28 Guanghui Li , Fangyuan Li , Barbara Lykke Lind , Rune W Berg

Mechanical strain and stress play a major role in biological processes such as wound healing or morphogenesis. To assess this role quantitatively, fixed or live images of tissues are acquired at a cellular precision in large fields of…

Tissues and Organs · Quantitative Biology 2019-06-12 M. Durande , S. Tlili , T. Homan , B. Guirao , F. Graner , H. Delanoë-Ayari

In recent years there has been substantial development in algorithms for quantum phase estimation. In this work we provide a new approach to online Bayesian phase estimation that achieves Heisenberg limited scaling that requires…

Quantum Physics · Physics 2022-08-10 Cassandra Granade , Nathan Wiebe

Accelerometry data has been widely used to measure activity and the circadian rhythm of individuals across the health sciences, in particular with people with advanced dementia. Modern accelerometers can record continuous observations on a…

Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative about the underlying biochemical processes of circadian…

Subcellular Processes · Quantitative Biology 2018-11-27 Hang-Hyun Jo , Yeon Jeong Kim , Jae Kyoung Kim , Mathias Foo , David E. Somers , Pan-Jun Kim

Forecasting multivariate time series data, such as prediction of electricity consumption, solar power production, and polyphonic piano pieces, has numerous valuable applications. However, complex and non-linear interdependencies between…

Machine Learning · Computer Science 2019-09-20 Shun-Yao Shih , Fan-Keng Sun , Hung-yi Lee

Membrane phase-separation is a mechanism that biological membranes often use to locally concentrate specific lipid species in order to organize diverse membrane processes. Phase separation has also been explored as a tool for the design of…

Computational Physics · Physics 2020-06-26 Alexander Zhiliakov , Yifei Wang , Annalisa Quaini , Maxim Olshanskii , Sheereen Majd

Neuromorphic systems typically employ current-mode circuits that model neural dynamics and produce output currents that range from few pico-Amperes to hundreds of micro-Amperes. On-line real-time monitoring of the signals produced by these…

Emerging Technologies · Computer Science 2019-08-20 Ning Qiao , Giacomo Indiveri

The circadian clock is the molecular mechanism responsible for the adaptation to daily rhythms in living organisms. Oscillations and fluctuations in environmental conditions regulate the circadian clock through signaling pathways. We study…

Biological Physics · Physics 2019-03-26 Andrea Auconi , Patrick Pett , Edda Klipp , Hanspeter Herzel

We discuss applications of nonlinear filtering of time series by locally linear phase space projections. Noise can be reduced whenever the error due to the manifold approximation is smaller than the noise in the system. Examples include the…

chao-dyn · Physics 2007-05-23 T. Schreiber , H. Kantz

Airflow signal encodes rich information about respiratory system. While the gold standard for measuring airflow is to use a spirometer with an occlusive seal, this is not practical for ambulatory monitoring of patients. Advances in sensor…

Machine Learning · Statistics 2020-08-12 Whitney K. Huang , Yu-Min Chung , Yu-Bo Wang , Jeff E. Mandel , Hau-Tieng Wu

Small continuous sensory and mechanical perturbations have often been used to identify properties of the closed-loop neural control of posture and other systems that are approximately linear time invariant. Here we extend this approach to…

Neurons and Cognition · Quantitative Biology 2016-10-31 Tim Kiemel , David Logan , John J. Jeka

A time-frequency diagram is a commonly used visualization for observing the time-frequency distribution of radio signals and analyzing their time-varying patterns of communication states in radio monitoring and management. While it excels…

Signal Processing · Electrical Eng. & Systems 2022-10-03 Ying Zhao , Luhao Ge , Huixuan Xie , Genghuai Bai , Zhao Zhang , Qiang Wei , Yun Lin , Yuchao Liu , Fangfang Zhou

In this paper we propose the Hatching-Box, a novel imaging and analysis system to automatically monitor and quantify the developmental behavior of Drosophila in standard rearing vials and during regular rearing routines, rendering explicit…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Julian Bigge , Maite Ogueta , Luis Garcia , Benjamin Risse