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The formation of microdomains, also called rafts, in biomembranes can be attributed to the surface tension of the membrane. In order to model this phenomenon, a model involving a coupling between the local composition and the local…

Analysis of PDEs · Mathematics 2016-06-29 Irene Fonseca , Gurgen Hayrapetyan , Giovanni Leoni , Barbara Zwicknagl

Random tilings of very large domains will typically lead to a solid, a liquid, and a gas phase. In the two-phase case, the solid-liquid boundary (arctic curve) is smooth, possibly with singularities. At the point of tangency of the arctic…

Mathematical Physics · Physics 2023-02-23 Mark Adler , Pierre van Moerbeke

Finsler geometric surface model is studied as a coarse-grained model for membranes of three-component such as DOPC, DPPC and Cholesterol. To understand the phase separation of liquid ordered (DPPC rich) $L_o$ and the liquid disordered (DOPC…

Soft Condensed Matter · Physics 2016-08-09 Satoshi Usui , Hiroshi Koibuchi

Proteins and nucleic acids can spontaneously self-assemble into membraneless droplet-like compartments, both in vitro and in vivo. A key component of these droplets are multi-valent proteins that possess several adhesive domains with…

Biomolecules · Quantitative Biology 2020-01-10 Srivastav Ranganathan , Eugene Shakhnovich

A model of lipid bilayers made of a mixture of two lipids with different average compositions on both leaflets, is developed. A Landau hamiltonian describing the lipid-lipid interactions on each leaflet, with two lipidic fields $\psi_1$ and…

Soft Condensed Matter · Physics 2014-08-28 Guillaume Gueguen , Nicolas Destainville , Manoel Manghi

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

We investigate the permeability of lipid membranes for fluorescence dyes and ions. We find that permeability reaches a maximum close to the chain melting transition of the membranes. Close to transitions, fluctuations in area and…

We study the stability and shapes of domains with spontaneous curvature in fluid films and membranes, embedded in a surrounding membrane with zero spontaneous curvature. These domains can result from the inclusion of an impurity in a fluid…

Soft Condensed Matter · Physics 2009-11-11 James L. Harden , Fred C. MacKintosh , Peter D. Olmsted

Observations show an almost ubiquitous presence of extra mixing in low-mass upper giant branch stars. The most commonly invoked explanation for this is thermohaline mixing. One-dimensional stellar evolution models include various…

Solar and Stellar Astrophysics · Physics 2022-12-28 Adrian E. Fraser , Meridith Joyce , Evan H. Anders , Jamie Tayar , Matteo Cantiello

The way living tissues respond to external mechanical forces is crucial in physiological processes like embryogenesis, homeostasis or tumor growth. Providing a complete description across length scales which relates the properties of…

Soft Condensed Matter · Physics 2025-11-07 Majid Layachi , Remi Merindol , Laura Casanellas

Over recent decades, lipid membranes have become standard models for examining the biophysics and biochemistry of cell membranes. Interrogation of lipid domains within biomembranes is generally done with fluorescence microscopy via…

Biological Physics · Physics 2018-03-30 Stephen H. Donaldson , Hilton B. de Aguiar

The domain formation of curvature-inducing molecules, such as peripheral or transmembrane proteins and conical surfactants, is studied in thermal equilibrium and nonequilibrium steady states using meshless membrane simulations. These…

Soft Condensed Matter · Physics 2023-01-30 Hiroshi Noguchi

Nanoscale membrane assemblies of sphingolipids, cholesterol, and certain proteins, also known as lipid rafts, play a crucial role in facilitating a broad range of important cell functions. Whereas on living cell membranes lipid rafts have…

A recently described technique (Estes and Mayer, Biochim. Biophys. Acta 1712 (2005) 152--160) for the preparation of giant unilamellar vesicles (GUVs) in solutions with high ionic strength is examined. By observing a series of osmotic…

Soft Condensed Matter · Physics 2009-02-18 Primoz Peterlin , Vesna Arrigler

Previous studies indicate that the properties of graphene oxide (GO) can be significantly improved by enhancing its graphitic domain size through thermal diffusion and clustering of functional groups. Remarkably, this transition takes place…

Biological membranes are known to form various structural motifs, from lipid bilayers to tubular filaments and networks facilitating e.g. adhesion and cell-cell communication. To understand the biophysical processes underpinning lipid-lipid…

Soft Condensed Matter · Physics 2025-12-30 David Regan , Paola Borri , Wolfgang Langbein

Understanding and engineering the domain boundaries in chemically vapor deposited (CVD) monolayer graphene will be critical for improving its properties. In this study, a combination of transmission electron microscopy (TEM) techniques…

This article summarizes a variety of physical mechanisms proposed in the literature, which can generate micro- and nanodomains in multicomponent lipid bilayers and biomembranes. It mainly focusses on lipid-driven mechanisms that do not…

Biological Physics · Physics 2016-11-16 Friederike Schmid

Using an interface displacement model derived from a microscopic density functional theory we investigate thin liquidlike wetting layers adsorbed on flat substrates with an embedded chemical heterogeneity forming a stripe. For a wide range…

Soft Condensed Matter · Physics 2009-10-31 C. Bauer , S. Dietrich , A. O. Parry

The intricate interplay of structural, charge and spin orders in layered cuprates leads to emergent phenomena, most notably high-temperature superconductivity. However, there is growing awareness that both the structure and electronic…

Superconductivity · Physics 2025-11-25 Mark S. Senn , Evie Ladbrook , Jon Wright