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One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a…

Populations and Evolution · Quantitative Biology 2015-05-19 Anna Melbinger , Massimo Vergassola

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

Among the wide variety of evolutionary computing models, Finite State Machines (FSMs) have several attractions for fundamental research. They are easy to understand in concept and can be visualised clearly in simple cases. They have a ready…

Neural and Evolutionary Computing · Computer Science 2023-10-23 Gabor Zoltai , Yue Xie , Frank Neumann

The running-time analysis of evolutionary combinatorial optimization is a fundamental topic in evolutionary computation. Its current research mainly focuses on specific algorithms for simplified problems due to the challenge posed by…

Neural and Evolutionary Computing · Computer Science 2025-01-14 Min Huang , Pengxiang Chen , Han Huang , Tonli He , Yushan Zhang , Zhifeng Hao

Existing theoretical models of evolution focus on the relative fitness advantages of different mutants in a population while the dynamic behavior of the population size is mostly left unconsidered. We here present a generic stochastic model…

Populations and Evolution · Quantitative Biology 2010-10-20 Anna Melbinger , Jonas Cremer , Erwin Frey

Kingman's model describes the evolution of a one-locus haploid population of infinite size and discrete generations under the competition of selection and mutation. A random generalisation has been made in a previous paper which assumes all…

Probability · Mathematics 2020-12-01 Linglong Yuan

Epistasis occurs when the effect of a mutation depends on its carrier's genetic background. Despite increasing evidence that epistasis for fitness is common, its role during evolution is contentious. Fitness landscapes, mappings of genotype…

Populations and Evolution · Quantitative Biology 2022-06-13 Claudia Bank

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

A model for the evolution of a finite population in a rugged fitness landscape is introduced and solved. The population is trapped in an evolutionary loop, alternating periods of stasis to periods in which it performs adaptive walks. The…

Disordered Systems and Neural Networks · Physics 2009-10-31 Luca Peliti

Darwinian evolution can be modeled in general terms as a flow in the space of fitness (i.e. reproductive rate) distributions. In the diffusion approximation, Tsimring et al. have showed that this flow admits "fitness wave" solutions:…

Populations and Evolution · Quantitative Biology 2017-01-30 Matteo Smerlak , Ahmed Youssef

Cumulative cultural evolution is what made humanity to thrive in various ecological and demographic environments. Solutions to the tasks that humans needed to solve could be mapped onto a task space which could take the form of either…

Computers and Society · Computer Science 2020-07-09 Masaki Suyama , Kosuke Sato

Ben-Ari and Schinazi (2016) introduced a stochastic model to study `virus-like evolving population with high mutation rate'. This model is a birth and death model with an individual at birth being either a mutant with a random fitness…

Probability · Mathematics 2020-01-03 Rahul Roy , Hideki Tanemura

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

In this article, a stochastic individual-based model describing Darwinian evolution of asexual, phenotypic trait-structured population, is studied. We consider a large population with constant population size characterised by a resampling…

Probability · Mathematics 2024-07-09 Nicolas Champagnat , Vincent Hass

Genotypic fitness landscapes are constructed by assessing the fitness of all possible combinations of a given number of mutations. In the last years, several experimental fitness landscapes have been completely resolved. As fitness…

Populations and Evolution · Quantitative Biology 2015-07-02 Luca Ferretti , Daniel Weinreich , Benjamin Schmiegelt , Atsushi Yamauchi , Yutaka Kobayashi , Fumio Tajima , Guillaume Achaz

Darwin's theory of evolution is considered to be one of the greatest scientific gems in modern science. It not only gives us a description of how living things evolve, but also shows how a population evolves through time and also, why only…

Machine Learning · Computer Science 2013-12-18 Arka Bhattacharya

Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of asexual organisms is coupled to molecular properties and…

Populations and Evolution · Quantitative Biology 2009-11-13 Muyoung Heo , Louis Kang , Eugene I. Shakhnovich

Constraints on changes in expression levels across all cell components imposed by the steady growth of cells have recently been discussed both experimentally and theoretically. By assuming a small environmental perturbation and considering…

Populations and Evolution · Quantitative Biology 2018-04-18 Chikara Furusawa , Kunihiko Kaneko

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi