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Today's sequencing technology allows sequencing an individual genome within a few weeks for a fraction of the costs of the original Human Genome project. Genomics labs are faced with dozens of TB of data per week that have to be…

Databases · Computer Science 2009-09-15 Uwe Roehm , Jose Blakeley

Machine Learning on Big Data gets more and more attention in various fields. Even so privacy-preserving techniques become more important, even necessary due to legal regulations such as the General Data Protection Regulation (GDPR). On the…

Cryptography and Security · Computer Science 2022-01-28 Jasmin Zalonis , Frederik Armknecht , Björn Grohmann , Manuel Koch

Portable genome sequencing technology is revolutionizing genomic research by providing a faster, more flexible method of sequencing DNA and RNA [1, 2]. The unprecedented shift from bulky stand-alone benchtop equipment confined in a…

Cryptography and Security · Computer Science 2024-07-18 Carson Stillman , Jonathan E. Bravo , Christina Boucher , Sara Rampazzi

When sharing sensitive relational databases with other parties, a database owner aims to (i) have privacy guarantees for the database entries, (ii) have liability guarantees (via fingerprinting) in case of unauthorized sharing of its…

Cryptography and Security · Computer Science 2022-03-08 Tianxi Ji , Erman Ayday , Emre Yilmaz , Pan Li

Data confidentiality is an important requirement for clients when outsourcing databases to the cloud. Trusted execution environments, such as Intel SGX, offer an efficient, hardware-based solution to this cryptographic problem. Existing…

Cryptography and Security · Computer Science 2020-02-13 Benny Fuhry , Jayanth Jain H A , Florian Kerschbaum

Blockchain has the potential to revolutionize the way we store, use, and process data. Information on most blockchains can be viewed by every node hosting the blockchain, which means that most blockchains cannot handle private data.…

Cryptography and Security · Computer Science 2018-10-30 Sabine Bertram , Co-Pierre Georg

Private queries allow a user Alice to learn an element of a database held by a provider Bob without revealing which element she was interested in, while limiting her information about the other elements. We propose to implement private…

This paper studies how a system operator and a set of agents securely execute a distributed projected gradient-based algorithm. In particular, each participant holds a set of problem coefficients and/or states whose values are private to…

Cryptography and Security · Computer Science 2018-05-24 Yang Lu , Minghui Zhu

Quantum computing has undergone rapid development in recent years. Owing to limitations on scalability, personal quantum computers still seem slightly unrealistic in the near future. The first practical quantum computer for ordinary users…

Cryptography and Security · Computer Science 2017-07-04 He-Liang Huang , You-Wei Zhao , Tan Li , Feng-Guang Li , Yu-Tao Du , Xiang-Qun Fu , Shuo Zhang , Xiang Wang , Wan-Su Bao

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

The trend towards delegating data processing to a remote party raises major concerns related to privacy violations for both end-users and service providers. These concerns have attracted the attention of the research community, and several…

Cryptography and Security · Computer Science 2015-12-15 Youssef Gahi , Mouhcine Guennoun , Zouhair Guennoun , Khalil El-khatib

Data is the lifeblood of AI, yet much of the most valuable data remains locked in silos due to privacy and regulations. As a result, AI remains heavily underutilized in many of the most important domains, including healthcare, education,…

Cryptography and Security · Computer Science 2026-02-11 Mayank Kumar , Qian Lou , Paulo Barreto , Martine De Cock , Sikha Pentyala

The database community, at least for the last decade, has been grappling with querying encrypted data, which would enable secure database as a service solutions. A recent breakthrough in the cryptographic community (in 2009) related to…

Databases · Computer Science 2013-02-13 Murali Mani , Kinnari Shah , Manikanta Gunda

In recent years, Whole Genome Sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a…

Cryptography and Security · Computer Science 2015-02-17 Erman Ayday , Emiliano De Cristofaro , Jean-Pierre Hubaux , Gene Tsudik

DNA fingerprinting and matching for identifying suspects has been a common practice in criminal investigation. Such proceedings involve multiple parties such as investigating agencies, suspects and forensic labs. A major challenge in such…

Cryptography and Security · Computer Science 2024-09-24 Sankha Das

The problem we address is the following: how can a user employ a predictive model that is held by a third party, without compromising private information. For example, a hospital may wish to use a cloud service to predict the readmission…

Machine Learning · Computer Science 2014-12-25 Pengtao Xie , Misha Bilenko , Tom Finley , Ran Gilad-Bachrach , Kristin Lauter , Michael Naehrig

Database users have started moving toward the use of cloud computing as a service because it provides computation and storage needs at affordable prices. However, for most of the users, the concern of privacy plays a major role as they…

Databases · Computer Science 2020-01-13 Sultan Almakdi , Brajendra Panda

Progress in Whole Genome Sequencing (WGS) will soon allow a large number of individuals to have their genome fully sequenced. This lays the foundations to improve modern healthcare, enabling a new era of personalized medicine where…

Cryptography and Security · Computer Science 2014-02-03 Emiliano De Cristofaro

FHE-SQL is a privacy-preserving database system that enables secure query processing on encrypted data using Fully Homomorphic Encryption (FHE), providing privacy guaranties where an untrusted server can execute encrypted queries without…

Cryptography and Security · Computer Science 2025-10-20 Po-Yu Tseng , Po-Chu Hsu , Shih-Wei Liao

Huge DBMSs storing genomic information are being created and engineerized for doing large-scale, comprehensive and in-depth analysis of human beings and their diseases. However, recent regulations like the GDPR require that sensitive data…

Data Structures and Algorithms · Computer Science 2020-12-29 Ferdinando Montecuollo , Giovannni Schmid