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In this paper, we focus on numerical methods for the genetic drift problems, which is governed by a degenerated convection-dominated parabolic equation. Due to the degeneration and convection, Dirac singularities will always be developed at…

Numerical Analysis · Mathematics 2016-12-13 Minxin Chen , Chun Liu , Shixin Xu , Xingye Yue , Ran Zhang

We propose and analyze an optimal mass transport method for a random genetic drift problem driven by a Moran process under weak-selection. The continuum limit, formulated as a reaction-advection-diffusion equation known as the Kimura…

Analysis of PDEs · Mathematics 2021-01-01 José A. Carrillo , Lin Chen , Qi Wang

In this paper, we propose a numerical method to uniformly handle the random genetic drift model for pure drift with or without natural selection and mutation. For pure drift and natural selection case, the Dirac $\delta$ singularity will…

Numerical Analysis · Mathematics 2023-10-27 Chenghua Duan , Chun Liu , Xingye Yue

The Energy-Dissipation Principle provides a variational tool for the analysis of parabolic evolution problems: solutions are characterized as so-called null-minimizers of a global functional on entire trajectories. This variational…

Analysis of PDEs · Mathematics 2021-09-14 Luca Scarpa , Ulisse Stefanelli

We propose a new continuum model for random genetic drift by employing a dynamic boundary condition approach. The model can be viewed as a regularized version of the Kimura equation and admits a continuous solution. We establish the…

Analysis of PDEs · Mathematics 2025-08-08 Chun Liu , Jan-Eric Sulzbach , Yiwei Wang

We propose numerical schemes for the approximate solution of problems defined on the edges of a one-dimensional graph. In particular, we consider linear transport and a drift-diffusion equations, and discretize them by extending Finite…

Numerical Analysis · Mathematics 2024-11-01 Beatrice Crippa , Anna Scotti , Andrea Villa

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

We study numerical methods for porous media equation (PME). There are two important characteristics: the finite speed propagation of the free boundary and the potential waiting time, which make the problem not easy to handle. Based on…

Numerical Analysis · Mathematics 2019-03-27 Chenghua Duan , Chun Liu , Cheng Wang , Xingye Yue

In this paper we develop a new approach to stochastic evolution equations with an unbounded drift $A$ which is dependent on time and the underlying probability space in an adapted way. It is well-known that the semigroup approach to…

Probability · Mathematics 2014-02-28 Matthijs Pronk , Mark Veraar

One of the fundamental mathematical models for studying random genetic drift is the Kimura equation, derived as the large-population limit of the discrete Wright-Fisher model. However, due to the degeneracy of the diffusion coefficient, it…

Numerical Analysis · Mathematics 2025-05-15 Chi-An Chen , Chun Liu , Yiwei Wang

The compact Genetic Algorithm (cGA), parameterized by its hypothetical population size $K$, offers a low-memory alternative to evolving a large offspring population of solutions. It evolves a probability distribution, biasing it towards…

Neural and Evolutionary Computing · Computer Science 2024-04-19 Cella Florescu , Marc Kaufmann , Johannes Lengler , Ulysse Schaller

We consider stochastic control with discretionary stopping for the drift of a diffusion process over an infinite time horizon. The objective is to choose a control process and a stopping time to minimize the expectation of a convex terminal…

Optimization and Control · Mathematics 2025-06-24 Václav E. Beneš , Georgy Gaitsgori , Ioannis Karatzas

We consider an optimal control problem on a bounded domain $\Omega\subset\mathbb{R}^2,$ governed by a parabolic convection--diffusion--reaction equation with pointwise control constraints. We follow the optimize--then--discretize approach,…

Numerical Analysis · Mathematics 2025-12-11 Christos Pervolianakis

Traditional Genetic Algorithms (GAs) mating schemes select individuals for crossover independently of their genotypic or phenotypic similarities. In Nature, this behaviour is known as random mating. However, non-random schemes - in which…

Neural and Evolutionary Computing · Computer Science 2009-09-30 C. M. Fernandes , J. J. Merelo , A. C. Rosa

Solving Quadratic equation is one of the intrinsic interests as it is the simplest nonlinear equations. A novel approach for solving Quadratic Equation based on Genetic Algorithms (GAs) is presented. Genetic Algorithms (GAs) are a technique…

Neural and Evolutionary Computing · Computer Science 2013-06-20 Tanistha Nayak , Tirtharaj Dash

Explicit numerical finite difference schemes for partial differential equations are well known to be easy to implement but they are particularly problematic for solving equations whose solutions admit shocks, blowups and discontinuities.…

Numerical Analysis · Mathematics 2016-10-19 Christopher. N. Angstmann , Bruce I. Henry , Byron A. Jacobs , Anna V. McGann

A numerical method is developed to solve the time-dependent Dirac equation in cylindrical coordinates for 3-D axisymmetric systems. The time evolution is treated by a splitting scheme in coordinate space using alternate direction iteration,…

Computational Physics · Physics 2015-04-03 François Fillion-Gourdeau , Emmanuel Lorin , André D. Bandrauk

Theory predicts rapid genetic drift during invasions, yet many expanding populations maintain high genetic diversity. We find that genetic drift is dramatically suppressed when dispersal rates increase with the population density because…

Populations and Evolution · Quantitative Biology 2019-03-29 Gabriel Birzu , Sakib Matin , Oskar Hallatschek , Kirill S. Korolev

In this work, we develop novel structure-preserving numerical schemes for a class of nonlinear Fokker--Planck equations with nonlocal interactions. Such equations can cover many cases of importance, such as porous medium equations with…

Numerical Analysis · Mathematics 2020-08-18 Chenghua Duan , Wenbin Chen , Chun Liu , Xingye Yue , Shenggao Zhou

In this article, we present a numerical approach to ensure the preservation of physical bounds on the solutions to linear and nonlinear hyperbolic convection-reaction problems at the discrete level. We provide a rigorous framework for error…

Numerical Analysis · Mathematics 2025-01-22 Ben S. Ashby , Abdalaziz Hamdan , Tristan Pryer
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