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Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Adrian Shajkofci , Michael Liebling

We present a variational Bayesian method of joint image reconstruction and point spread function (PSF) estimation when the PSF of the imaging device is only partially known. To solve this semi-blind deconvolution problem, prior…

Data Analysis, Statistics and Probability · Physics 2013-03-18 Se Un Park , Nicolas Dobigeon , Alfred O. Hero

This paper demonstrates a practical method that can correct spatial varying blur from a set of images of the same object. The algorithm jointly estimates the object and local point spread functions~(PSF). The method prioritizes sections…

Image and Video Processing · Electrical Eng. & Systems 2020-11-04 Wouter van de Ketterij , Oleg Soloviev , Michel Verhaegen

The quality of microscopy images often suffers from optical aberrations. These aberrations and their associated point spread functions have to be quantitatively estimated to restore aberrated images. The recent state-of-the-art method…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Kira Vinogradova , Eugene W. Myers

We propose a solution to the image deconvolution problem where the convolution kernel or point spread function (PSF) is assumed to be only partially known. Small perturbations generated from the model are exploited to produce a few…

Data Analysis, Statistics and Probability · Physics 2015-06-04 Se Un Park , Nicolas Dobigeon , Alfred O. Hero

We study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function (PSF) of a…

Deconvolution is the most commonly used image processing method to remove the blur caused by the point-spread-function (PSF) in optical imaging systems. While this method has been successful in deblurring, it suffers from several…

Image and Video Processing · Electrical Eng. & Systems 2019-10-10 Huangxuan Zhao , Ziwen Ke , Ningbo Chen , Ke Li , Lidai Wang , Xiaojing Gong , Wei Zheng , Liang Song , Zhicheng Liu , Dong Liang , Chengbo Liu

We proposed a deconvolution optical-resolution photoacoustic microscope for high -resolution imaging of brain. The focal spot of the photoacoustic microscopy is measured to obtain the lateral PSF (point spread function) of the system.…

Medical Physics · Physics 2020-11-05 Xianlin Song , Lingfang Song , Anqing Chen , Jianshuang Wei

A point-spread function describes the optics of an imaging system and can be used to correct collected images for instrumental effects. The state of the art for deconvolving images with the point-spread function is the Richardson-Lucy…

Instrumentation and Methods for Astrophysics · Physics 2024-05-07 Stefan Johann Hofmeister

Due to limited size and imperfect of the optical components in a spectrometer, aberration has inevitably been brought into two-dimensional multi-fiber spectrum image in LAMOST, which leads to obvious spacial variation of the point spread…

Instrumentation and Methods for Astrophysics · Physics 2020-10-28 Jiali Xu , Qian Yin , Ping Guo , Xin Zheng

We have shown that the left side null space of the autoregression (AR) matrix operator is the lexicographical presentation of the point spread function (PSF) on condition the AR parameters are common for original and blurred images. The…

Computer Vision and Pattern Recognition · Computer Science 2012-06-19 Yu. A. Bunyak , O. Yu. Sofina , R. N. Kvetnyy

Optical astronomical images are strongly affected by the point spread function (PSF) of the optical system and the atmosphere (seeing) which blurs the observed image. The amount of blurring depends both on the observed band, and on the…

Instrumentation and Methods for Astrophysics · Physics 2023-08-31 Hong Wang , Sreevarsha Sreejith , Yuewei Lin , Nesar Ramachandra , Anže Slosar , Shinjae Yoo

Deconvolution is the most widely used aberration correction technique in microscopy, however most techniques assume that the aberrations are the same for each point in the image, which is rarely true. Methods for tracking spatially varying…

Optics · Physics 2025-12-02 Jakub Czuchnowski , Chuan Li , Hongli Ni , Brandon Weissbourd , Jerome Mertz

A method for spatial deconvolution of spectra is presented. It follows the same fundamental principles as the ``MCS image deconvolution algorithm'' (Magain, Courbin, Sohy, 1998) and uses information contained in the spectrum of a reference…

Astrophysics · Physics 2009-10-31 F. Courbin , P. Magain , M. Kirkove , S. Sohy

Microscopy is one of the most essential imaging techniques in life sciences. High-quality images are required in order to solve (potentially life-saving) biomedical research problems. Many microscopy techniques do not achieve sufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jan Aelterman , Jonas De Vylder , Hiep Luong , Yvan Saeys , Wilfried Philips

We investigate possibilities to speed up iterative algorithms for non-blind image deconvolution. We focus on algorithms in which convolution with the point-spread function to be deconvolved is used in each iteration, and aim at accelerating…

Computer Vision and Pattern Recognition · Computer Science 2013-04-29 Martin Welk , Martin Erler

A major issue in optical astronomical image analysis is the combined effect of the instrument's point spread function (PSF) and the atmospheric seeing that blurs images and changes their shape in a way that is band and time-of-observation…

Instrumentation and Methods for Astrophysics · Physics 2024-10-02 Sreevarsha Sreejith , Anže Slosar , Hong Wang

Access to knowledge of the point spread function (PSF) of adaptive optics(AO)-assisted observations is still a major limitation when processing AO data. This limitation is particularly important when image analysis requires the use of…

Instrumentation and Methods for Astrophysics · Physics 2023-05-10 A. Lau , R. JL. Fétick , B. Neichel , O. Beltramo-Martin , T. Fusco

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

Deconvolution microscopy has been extensively used to improve the resolution of the widefield fluorescent microscopy. Conventional approaches, which usually require the point spread function (PSF) measurement or blind estimation, are…

Machine Learning · Computer Science 2019-04-08 Sungjun Lim , Sang-Eun Lee , Sunghoe Chang , Jong Chul Ye
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