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Capturing aleatoric uncertainty is a critical part of many machine learning systems. In deep learning, a common approach to this end is to train a neural network to estimate the parameters of a heteroscedastic Gaussian distribution by…

Machine Learning · Computer Science 2022-04-04 Maximilian Seitzer , Arash Tavakoli , Dimitrije Antic , Georg Martius

Probabilistic models analyze data by relying on a set of assumptions. Data that exhibit deviations from these assumptions can undermine inference and prediction quality. Robust models offer protection against mismatch between a model's…

Machine Learning · Statistics 2018-06-20 Yixin Wang , Alp Kucukelbir , David M. Blei

Random-effects models are frequently used to synthesise information from different studies in meta-analysis. While likelihood-based inference is attractive both in terms of limiting properties and of implementation, its application in…

Methodology · Statistics 2018-02-16 Ioannis Kosmidis , Annamaria Guolo , Cristiano Varin

Labeling patients in electronic health records with respect to their statuses of having a disease or condition, i.e. case or control statuses, has increasingly relied on prediction models using high-dimensional variables derived from…

Methodology · Statistics 2021-10-14 Zijian Guo , Prabrisha Rakshit , Daniel S. Herman , Jinbo Chen

In this paper we discuss how to evaluate the differences between fitted logistic regression models across sub-populations. Our motivating example is in studying computerized diagnosis for learning disabilities, where sub-populations based…

Methodology · Statistics 2023-03-24 Guy Ashiri-Prossner , Yuval Benjamini

Regression analysis based on many covariates is becoming increasingly common. However, when the number of covariates $p$ is of the same order as the number of observations $n$, maximum likelihood regression becomes unreliable due to…

Methodology · Statistics 2023-09-06 Emanuele Massa , Marianne Jonker , Kit Roes , Anthony Coolen

Consider a set of categorical variables $\mathcal{P}$ where at least one, denoted by $Y$, is binary. The log-linear model that describes the counts in the resulting contingency table implies a specific logistic regression model, with the…

Methodology · Statistics 2019-12-04 Wei Jing , Michail Papathomas

Firth-type logistic regression has become a standard approach for the analysis of binary outcomes with small samples. Whereas it reduces the bias in maximum likelihood estimates of coefficients, bias towards 1/2 is introduced in the…

Methodology · Statistics 2021-01-20 Rainer Puhr , Georg Heinze , Mariana Nold , Lara Lusa , Angelika Geroldinger

The exact maximum likelihood estimate (MLE) provides a test statistic for the unit root test that is more powerful \citep[p. 577]{Fuller96} than the usual least squares approach. In this paper a new derivation is given for the asymptotic…

Statistics Theory · Mathematics 2016-11-04 Ying Zhang , H. Yu , A. I. McLeod

The choice of free parameters in network models is subjective, since it depends on what topological properties are being monitored. However, we show that the Maximum Likelihood (ML) principle indicates a unique, statistically rigorous…

Disordered Systems and Neural Networks · Physics 2008-08-07 Diego Garlaschelli , Maria I. Loffredo

There is a considerable literature in case-control logistic regression on whether or not non-confounding covariates should be adjusted for. However, only limited and ad hoc theoretical results are available on this important topic. A…

Statistics Theory · Mathematics 2023-05-19 Siliang Zhang , Jinbo Chen , Zhiliang Ying , Hong Zhang

Maximum likelihood estimation (MLE) is a fundamental computational problem in statistics. In this paper, MLE for statistical models with discrete data is studied from an algebraic statistics viewpoint. A reformulation of the MLE problem in…

Statistics Theory · Mathematics 2014-05-27 Jose Israel Rodriguez

Contemporary machine learning applications often involve classification tasks with many classes. Despite their extensive use, a precise understanding of the statistical properties and behavior of classification algorithms is still missing,…

Machine Learning · Computer Science 2020-11-17 Christos Thrampoulidis , Samet Oymak , Mahdi Soltanolkotabi

Machine-Learned Likelihoods (MLL) combines machine-learning classification techniques with likelihood-based inference tests to estimate the experimental sensitivity of high-dimensional data sets. We extend the MLL method by including Kernel…

High Energy Physics - Phenomenology · Physics 2023-12-18 Ernesto Arganda , Andres D. Perez , Martin de los Rios , Rosa María Sandá Seoane

In this paper, we consider distributed maximum likelihood estimation (MLE) with dependent quantized data under the assumption that the structure of the joint probability density function (pdf) is known, but it contains unknown deterministic…

Information Theory · Computer Science 2013-09-17 Xiaojing Shen , Pramod K. Varshney , Yunmin Zhu

The linear regression model with a random variable (RV) measurement matrix, where the mean of the random measurement matrix has full column rank, has been extensively studied. In particular, the quasiconvexity of the maximum likelihood…

Signal Processing · Electrical Eng. & Systems 2025-07-16 Ruohai Guo , Jiang Zhu , Xing Jiang , Fengzhong Qu

This paper develops a unified estimation framework, the Maximum Ideal Likelihood Estimation (MILE), for general parametric models with latent variables. Unlike traditional approaches relying on the marginal likelihood of the observed data,…

Statistics Theory · Mathematics 2025-10-08 Yizhou Cai , Ting Fung Ma

Large Language Models (LLMs) can propose rules in natural language, sidestepping the need for a predefined predicate space in traditional rule learning. Yet many LLM-based approaches ignore interactions among rules, and the opportunity to…

Artificial Intelligence · Computer Science 2026-02-16 Yang Yang , Hua XU , Zhangyi Hu , Yutao Yue

An important challenge in statistical analysis concerns the control of the finite sample bias of estimators. For example, the maximum likelihood estimator has a bias that can result in a significant inferential loss. This problem is…

Statistics Theory · Mathematics 2019-11-04 Stéphane Guerrier , Mucyo Karemera , Samuel Orso , Maria-Pia Victoria-Feser

The behavior of maximum likelihood estimates (MLEs) and the likelihood ratio statistic in a family of problems involving pointwise nonparametric estimation of a monotone function is studied. This class of problems differs radically from the…

Statistics Theory · Mathematics 2009-09-29 Moulinath Banerjee