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Penalized regression methods are an attractive tool for high-dimensional data analysis, but their widespread adoption has been hampered by the difficulty of applying inferential tools. In particular, the question "How reliable is the…

Statistics Theory · Mathematics 2026-05-13 Patrick Breheny

We show that the control of the false discovery rate (FDR) for a multiple testing procedure is implied by two coupled simple sufficient conditions. The first one, which we call ``self-consistency condition'', concerns the algorithm itself,…

Statistics Theory · Mathematics 2008-10-21 Gilles Blanchard , Etienne Roquain

With the rapid growth of crowdsourcing platforms it has become easy and relatively inexpensive to collect a dataset labeled by multiple annotators in a short time. However due to the lack of control over the quality of the annotators, some…

Machine Learning · Statistics 2016-06-17 Qianqian Xu , Jiechao Xiong , Xiaochun Cao , Yuan Yao

Differential privacy provides a rigorous framework for privacy-preserving data analysis. This paper proposes the first differentially private procedure for controlling the false discovery rate (FDR) in multiple hypothesis testing. Inspired…

Statistics Theory · Mathematics 2021-07-06 Cynthia Dwork , Weijie J. Su , Li Zhang

Improved procedures, in terms of smaller missed discovery rates (MDR), for performing multiple hypotheses testing with weak and strong control of the family-wise error rate (FWER) or the false discovery rate (FDR) are developed and studied.…

Statistics Theory · Mathematics 2011-03-10 Edsel A. Peña , Joshua D. Habiger , Wensong Wu

Motivated by the genomic application of expression quantitative trait loci (eQTL) mapping, we propose a new procedure to perform simultaneous testing of multiple hypotheses using Bayes factors as input test statistics. One of the most…

Methodology · Statistics 2016-06-09 Xiaoquan Wen

When many (m) null hypotheses are tested with a single dataset, the control of the number of false rejections is often the principal consideration. Two popular controlling rates are the probability of making at least one false discovery…

Methodology · Statistics 2013-07-11 Djalel Eddine Meskaldji , Jean-Philippe Thiran , Stephan Morgenthaler

We propose a new empirical Bayes method for covariate-assisted multiple testing with false discovery rate (FDR) control, where we model the local false discovery rate for each hypothesis as a function of both its covariates and p-value. Our…

Methodology · Statistics 2021-07-01 Patrick Chao , William Fithian

The False Discovery Rate (FDR) paradigm aims to attain certain control on Type I errors with relatively high power for multiple hypothesis testing. The Benjamini--Hochberg (BH) procedure is a well-known FDR controlling procedure. Under a…

Statistics Theory · Mathematics 2007-11-06 Zhiyi Chi

Most link prediction methods return estimates of the connection probability of missing edges in a graph. Such output can be used to rank the missing edges from most to least likely to be a true edge, but does not directly provide a…

Methodology · Statistics 2024-03-26 Ariane Marandon

The topological gap protocol (TGP) is a statistical test designed to identify a topological phase with high confidence and without human bias. It is used to determine a promising parameter regime for operating topological qubits. The…

Mesoscale and Nanoscale Physics · Physics 2025-04-21 Morteza Aghaee , Zulfi Alam , Mariusz Andrzejczuk , Andrey E. Antipov , Mikhail Astafev , Amin Barzegar , Bela Bauer , Jonathan Becker , Umesh Kumar Bhaskar , Alex Bocharov , Srini Boddapati , David Bohn , Jouri Bommer , Leo Bourdet , Samuel Boutin , Benjamin J. Chapman , Sohail Chatoor , Anna Wulff Christensen , Patrick Codd , William S. Cole , Paul Cooper , Fabiano Corsetti , Ajuan Cui , Andreas Ekefjärd , Saeed Fallahi , Luca Galletti , Geoff Gardner , Deshan Govender , Flavio Griggio , Ruben Grigoryan , Sebastian Grijalva , Sergei Gronin , Jan Gukelberger , Marzie Hamdast , Esben Bork Hansen , Sebastian Heedt , Samantha Ho , Laurens Holgaard , Kevin Van Hoogdalem , Jinnapat Indrapiromkul , Henrik Ingerslev , Lovro Ivancevic , Thomas Jensen , Jaspreet Jhoja , Jeffrey Jones , Konstantin V. Kalashnikov , Ray Kallaher , Rachpon Kalra , Farhad Karimi , Torsten Karzig , Maren Elisabeth Kloster , Christina Knapp , Jonne Koski , Pasi Kostamo , Tom Laeven , Gijs de Lange , Thorvald Larsen , Jason Lee , Kyunghoon Lee , Grant Leum , Kongyi Li , Tyler Lindemann , Matthew Looij , Marijn Lucas , Roman Lutchyn , Morten Hannibal Madsen , Nash Madulid , Michael Manfra , Signe Brynold Markussen , Esteban Martinez , Marco Mattila , Robert McNeil , Ryan V. Mishmash , Gopakumar Mohandas , Christian Mollgaard , Michiel de Moor , Trevor Morgan , George Moussa , Chetan Nayak , William Hvidtfelt Padkær Nielsen , Jens Hedegaard Nielsen , Mike Nystrom , Eoin O'Farrell , Keita Otani , Karl Petersson , Luca Petit , Dima Pikulin , Mohana Rajpalke , Alejandro Alcaraz Ramirez , Katrine Rasmussen , David Razmadze , Yuan Ren , Ken Reneris , Ivan A. Sadovskyy , Lauri Sainiemi , Juan Carlos Estrada Saldaña , Irene Sanlorenzo , Emma Schmidgall , Cristina Sfiligoj , Sarat Sinha , Thomas Soerensen , Patrick Sohr , Tomaš Stankevič , Lieuwe Stek , Eric Stuppard , Henri Suominen , Judith Suter , Sam Teicher , Nivetha Thiyagarajah , Raj Tholapi , Mason Thomas , Emily Toomey , Josh Tracy , Michelle Turley , Shivendra Upadhyay , Ivan Urban , Dmitrii V. Viazmitinov , Dominik Vogel , John Watson , Alex Webster , Joseph Weston , Georg W. Winkler , David J. Van Woerkom , Brian Paquelet Wütz , Chung Kai Yang , Emrah Yucelen , Jesús Herranz Zamorano , Roland Zeisel , Guoji Zheng , Justin Zilke

Selecting relevant features associated with a given response variable is an important issue in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent…

Methodology · Statistics 2020-12-17 Chenguang Dai , Buyu Lin , Xin Xing , Jun S. Liu

Multiple testing problems arising in modern scientific applications can involve simultaneously testing thousands or even millions of hypotheses, with relatively few true signals. In this paper, we consider the multiple testing problem where…

Methodology · Statistics 2016-06-28 Ang Li , Rina Foygel Barber

We introduce an Integrative Ranking and Thresholding (IRT) framework for fusing evidence from multiple testing procedures. The key innovation is a method that transforms binary testing decisions into compound $e-$values, enabling the…

Methodology · Statistics 2025-09-04 Trambak Banerjee , Bowen Gang , Jianliang He

We develop a flexible feature selection framework based on deep neural networks that approximately controls the false discovery rate (FDR), a measure of Type-I error. The method applies to architectures whose first layer is fully connected.…

Machine Learning · Statistics 2026-02-10 Kazuma Sawaya

We consider the problem of variable selection in high-dimensional statistical models where the goal is to report a set of variables, out of many predictors $X_1, \dotsc, X_p$, that are relevant to a response of interest. For linear…

Methodology · Statistics 2019-03-20 Adel Javanmard , Hamid Javadi

The false discovery rate (FDR) measures the share of false positives in a set of statistical tests. I develop simple and intuitive bounds on the FDR in cross-sectional predictability publications. The simplest bound requires just a few…

General Finance · Quantitative Finance 2025-11-20 Andrew Y. Chen

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

Signal Processing · Electrical Eng. & Systems 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

In many scenarios such as genome-wide association studies where dependences between variables commonly exist, it is often of interest to infer the interaction effects in the model. However, testing pairwise interactions among millions of…

Methodology · Statistics 2022-09-02 Jingyi Duan , Yang Ning , Xi Chen , Yong Chen

One important partition of algorithms for controlling the false discovery rate (FDR) in multiple testing is into offline and online algorithms. The first generally achieve significantly higher power of discovery, while the latter allow…

Methodology · Statistics 2021-03-05 Tijana Zrnic , Daniel L. Jiang , Aaditya Ramdas , Michael I. Jordan
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