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Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects, are of interest because they may highlight genes associated…

Statistics Theory · Mathematics 2014-03-11 Vonn Walter , Fred A. Wright , Andrew B. Nobel

Sample correlation matrices are employed ubiquitously in statistics. However, quite surprisingly, little is known about their asymptotic spectral properties for high-dimensional data, particularly beyond the case of "null models" for which…

Statistics Theory · Mathematics 2019-03-13 David Morales-Jimenez , Iain M. Johnstone , Matthew R. McKay , Jeha Yang

Given two networks of differing sizes, it is of interest to test whether the two networks belong to the same distribution. We formalize the notion of "equality of distribution" under the framework of the generalized random dot product…

Statistics Theory · Mathematics 2026-03-10 Joshua Agterberg , Minh Tang , Carey Priebe

We are interested in the problem of two-sample network hypothesis testing: given two networks with the same set of nodes, we wish to test whether the underlying Bernoulli probability matrices of the two networks are the same or not. We…

Methodology · Statistics 2024-08-14 Jiashun Jin , Zheng Tracy Ke , Shengming Luo , Yucong Ma

The problem of testing the equality of mean vectors for high-dimensional data has been intensively investigated in the literature. However, most of the existing tests impose strong assumptions on the underlying group covariance matrices…

Statistics Theory · Mathematics 2022-12-29 Tianming Zhu , Pengfei Wang , Jin-Ting Zhang

Pooled analyses that aggregate data from multiple studies are becoming increasingly common in collaborative epidemiologic research in order to increase the size and diversity of the study population. However, biomarker measurements from…

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

Methodology · Statistics 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

Given a random sample of size $n$ from a $p$ dimensional random vector, where both $n$ and $p$ are large, we are interested in testing whether the $p$ components of the random vector are mutually independent. This is the so-called complete…

Statistics Theory · Mathematics 2022-01-24 Yongcheng Qi , Yingchao Zhou

The comparison of a parameter in $k$ populations is a classical problem in statistics. Testing for the equality of means or variances are typical examples. Most procedures designed to deal with this problem assume that $k$ is fixed and that…

Testing cross-sectional independence in panel data models is of fundamental importance in econometric analysis with high-dimensional panels. Recently, econometricians began to turn their attention to the problem in the presence of serial…

Methodology · Statistics 2023-09-18 Hongfei Wang , Binghui Liu , Long Feng , Yanyuan Ma

We propose a new asymptotic test for the separability of a covariance matrix. The null distribution is valid in wide matrix elliptical model that includes, in particular, both matrix Gaussian and matrix $t$-distribution. The test is fast to…

Statistics Theory · Mathematics 2026-01-26 Joni Virta , Takeru Matsuda

We consider statistical procedures for hypothesis testing of real valued functionals of matched pairs with missing values. In order to improve the accuracy of existing methods, we propose a novel multiplication combination procedure.…

Statistics Theory · Mathematics 2018-01-29 Lubna Amro , Frank Konietschke , Markus Pauly

Strong mixing property holds for a broad class of linear and nonlinear time series models such as ARMA and GARCH models. In this article we study correlation structure of strong mixing sequences, and some asymptotic properties are…

Statistics Theory · Mathematics 2012-03-02 Fatemeh Azizzadeh , Saeid Rezakhah

Correlation testing provides a quick method of discriminating amongst potential terms to include in a nuclear mass formula or functional and is a necessary tool for further nuclear mass models; however a firm mathematical foundation of the…

Nuclear Theory · Physics 2013-05-14 M. G. Bertolli

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

Methodology · Statistics 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

Tests of equality of copulas between two samples are introduced and studied using the empirical Bernstein copula process. Three statistics are proposed and their asymptotic properties are established. Besides, a subsampling Bernstein…

Statistics Theory · Mathematics 2023-12-19 Guanjie Lyu , Mohamed Belalia

Heterogeneity in the cell population of cancer tissues poses many challenges in cancer diagnosis and treatment. Studying the heterogeneity in cell populations from gene expression measurement data in the context of cancer research is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Anik Chaudhuri , Anwoy Mohanty , Manoranjan Satpathy

Correlation analysis is a fundamental problem in statistics. In this paper, we consider the correlation detection problem between a pair of Erdos-Renyi graphs. Specifically, the problem is formulated as a hypothesis testing problem: under…

Statistics Theory · Mathematics 2026-01-21 Dong Huang , Pengkun Yang

This paper investigates the theoretical and empirical performance of Fisher-Pitman-type permutation tests for assessing the equality of unknown Poisson mixture distributions. Building on nonparametric maximum likelihood estimators (NPMLEs)…

Methodology · Statistics 2021-06-08 Zhen Miao , Weihao Kong , Ramya Korlakai Vinayak , Wei Sun , Fang Han

In The Cancer Genome Atlas (TCGA) data set, there are many interesting nonlinear dependencies between pairs of genes that reveal important relationships and subtypes of cancer. Such genomic data analysis requires a rapid, powerful and…

Applications · Statistics 2022-11-30 Siqi Xiang , Wan Zhang , Siyao Liu , Katherine A. Hoadley , Charles M. Perou , Kai Zhang , J. S. Marron