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We apply monomer-resolved computer simulations of supercoiled ring polymers under shear, taking full account of the hydrodynamic interactions, accompanied, in parallel, by simulations in which these are switched off. The combination of…

Soft Condensed Matter · Physics 2024-04-17 Christoph Schneck , Jan Smrek , Christos N. Likos , Andreas Zöttl

Understanding interactions between microparticles and lipid membranes is of increasing importance, especially for unraveling the influence of microplastics on our health and environment. Here, we study how a short-ranged adhesive force…

Soft Condensed Matter · Physics 2017-10-11 Casper van der Wel , Doris Heinrich , Daniela J. Kraft

We study the dynamics of the phase behavior of a polymer blend in the presence of shear flow. By adopting a two fluid picture and using a generalization of the concept of material derivative, we construct kinetic equations that describe the…

Soft Condensed Matter · Physics 2009-10-30 Tao Sun , Anna C. Balazs , David Jasnow

Intermolecular forces are known to precipitate adhesion events between solid bodies. Inspired by a macro-scale experiment showing the hysteretic adhesion of a piece of flexible tape over a plastic substrate, we develop here a model of…

Soft Condensed Matter · Physics 2009-07-05 Arthur A. Evans , Eric Lauga

This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated…

Biological Physics · Physics 2014-12-17 Markus Deserno , Kurt Kremer , Harald Paulsen , Christine Peter , Friederike Schmid

A self-consistent model is developed to investigate attachment / detachment kinetics of two soft, deformable microspheres with irregular surface and coated with flexible binding ligands. The model highlights how the microscale binding…

Cell Behavior · Quantitative Biology 2015-10-13 Sarthok Sircar , Andrei Kotousov , Giang Nguyen , Anthony J. Roberts

The system of polymers in solvent mixtures is a widely-used model to represent biomolecular condensates in intracellular environments. Here, we apply a variational theory to control the center-of-mass of two polymers and perform the first…

Soft Condensed Matter · Physics 2025-02-28 Luofu Liu , Rui Wang

We present a multi-scale model to study the attachment of spherical particles with a rigid core, coated with binding ligands and in equilibrium with the surrounding, quiescent fluid medium. This class of fluid-immersed adhesion is…

Biological Physics · Physics 2013-09-10 Sarthok Sircar , John G. Younger , David M. Bortz

Continuum elasticity is a powerful tool applicable in a broad range of physical systems and phenomena. Yet, understanding how and on what scales material disorder may lead to the breakdown of continuum elasticity is not fully understood. We…

Soft Condensed Matter · Physics 2023-04-11 Edan Lerner , Eran Bouchbinder

Contact unit size reduction is a widely studied mechanism as a means to improve adhesion in natural fibrillar systems, such as those observed in beetles or geckos. However, these animals also display complex structural features in the way…

Soft Condensed Matter · Physics 2018-06-22 Lucas Brely , Federico Bosia , Nicola M. Pugno

Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…

Fluid Dynamics · Physics 2010-07-06 Petia M. Vlahovska , Yuan-nan Young , Gerrit Danker , Chaouqi Misbah

We develop a stochastic kinetic model of a pre-formed attachment of a mictrotuble (MT) with a cell cortex, in which the MT is tethered to the cell by a group of active motor proteins. Such an attachment is a particularly unique case of…

Subcellular Processes · Quantitative Biology 2018-10-31 Dipanwita Ghanti , Raymond W. Friddle , Debashish Chowdhury

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…

Mechanical forces such as fluid shear have been shown to enhance cell growth and differentiation, but knowledge of their mechanistic effect on cells is limited because the local flow patterns and associated metrics are not precisely known.…

Large-scale simulations of thermal welding of polymers are performed to investigate the rise of mechanical strength at the polymer-polymer interface with the welding time. The welding process is in the core of integrating polymeric elements…

Soft Condensed Matter · Physics 2012-11-30 Ting Ge , Flint Pierce , Dvora Perahia , Gary S. Grest , Mark O. Robbins

When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering…

Tissues and Organs · Quantitative Biology 2015-06-18 Ziheng Wu , Zhiliang Xu , Oleg Kim , Mark Alber

The dynamics of elastocapillary thinning in high molecular weight polymer solutions are re-examined using high-speed digital video microscopy. At long times, the evolution of the viscoelastic thread deviates from self-similar exponential…

Other Condensed Matter · Physics 2009-11-11 Monica S. N. Oliveira , Gareth H. McKinley

We investigated the influence of short- and long-range correlated quenched disorder introduced into the medium on the process of adsorption of long-flexible polymer chains on a wall by using the field theoretical approach in $d=4-\epsilon$…

Disordered Systems and Neural Networks · Physics 2007-05-23 Z. Usatenko , A. Ciach

Reconstituted filamentous actin networks with myosin motor proteins form active gels, in which motor proteins generate forces that drive the network far from equilibrium. This motor activity can also strongly affect the network elasticity;…

Soft Condensed Matter · Physics 2010-09-21 C. P. Broedersz , F. C. MacKintosh

The dynamical mechanical analysis of blood generally uses models inspired by conventional flows, assuming scale-independent homogeneous flows and without considering fluid-surface boundary interactions. The present experimental study…

Fluid Dynamics · Physics 2024-09-24 Ursula Windberger , Patrick Baroni , Laurence Noirez