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We propose a numerical technique for parameter inference in Markov models of biological processes. Based on time-series data of a process we estimate the kinetic rate constants by maximizing the likelihood of the data. The computation of…

Quantitative Methods · Quantitative Biology 2011-02-15 Aleksandr Andreychenko , Linar Mikeev , David Spieler , Verena Wolf

Mathematical modeling of production systems is the foundation of all model-based approaches for production system analysis, design, improvement, and control. To construct such a model for the stochastic process of the production system more…

Systems and Control · Electrical Eng. & Systems 2024-05-22 Yuting Sun , Liang Zhang

We present a system for online probabilistic event forecasting. We assume that a user is interested in detecting and forecasting event patterns, given in the form of regular expressions. Our system can consume streams of events and forecast…

Databases · Computer Science 2018-12-18 Elias Alevizos , Alexander Artikis , Georgios Paliouras

Empirical analysis serves as an important complement to theoretical analysis for studying practical Bayesian optimization. Often empirical insights expose strengths and weaknesses inaccessible to theoretical analysis. We define two metrics…

Machine Learning · Computer Science 2016-04-01 Ian Dewancker , Michael McCourt , Scott Clark , Patrick Hayes , Alexandra Johnson , George Ke

In this paper, we present a generalized version of the matrix chain algorithm to generate efficient code for linear algebra problems, a task for which human experts often invest days or even weeks of works. The standard matrix chain problem…

Mathematical Software · Computer Science 2018-04-12 Henrik Barthels , Marcin Copik , Paolo Bientinesi

Scientific workloads are often described as directed acyclic task graphs. In this paper, we focus on the multifrontal factorization of sparse matrices, whose task graph is structured as a tree of parallel tasks. Among the existing models…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-06-05 Abdou Guermouche , Loris Marchal , Bertrand Simon , Frédéric Vivien

The covariance matrix of measurements of Markov random fields (processes) has useful properties that allow to develop effective computational algorithms for many problems in the study of Markov fields on the basis of field observations…

Information Theory · Computer Science 2018-04-04 Ulan N. Brimkulov , Chinara Jumabaeva , Kasym Baryktabasov

Tensor structured Markov chains are part of stochastic models of many practical applications, e.g., in the description of complex production or telephone networks. The most interesting question in Markov chain models is the determination of…

Numerical Analysis · Mathematics 2015-05-08 Matthias Bolten , Karsten Kahl , Sonja Sokolović

We propose a new Markov chain Monte Carlo method in which trial configurations are generated by evolving a state, sampled from a prior distribution, using a Markov transition matrix. We present two prototypical algorithms and derive their…

Statistical Mechanics · Physics 2023-01-09 Joel Mabillard , Isha Malhotra , Bortolo Matteo Mognetti

This paper presents a simple algorithm to check whether reachability probabilities in parametric Markov chains are monotonic in (some of) the parameters. The idea is to construct - only using the graph structure of the Markov chain and…

Logic in Computer Science · Computer Science 2019-07-22 Jip Spel , Sebastian Junges , Joost-Pieter Katoen

Many product lines are critical, and therefore reliability is a vital part of their requirements. Reliability is a probabilistic property. We therefore propose a model for feature-aware discrete-time Markov chains as a basis for verifying…

Software Engineering · Computer Science 2013-11-07 Maxime Cordy , Patrick Heymans , Pierre-Yves Schobbens , Amir Molzam Sharifloo , Carlo Ghezzi , Axel Legay

As the size of engineered systems grows, problems in reliability theory can become computationally challenging, often due to the combinatorial growth in the cut sets. In this paper we demonstrate how Multilevel Monte Carlo (MLMC) - a…

Computation · Statistics 2017-03-14 Louis J. M. Aslett , Tigran Nagapetyan , Sebastian J. Vollmer

Replication of experimental results has been a challenge faced by many scientific disciplines, including the field of machine learning. Recent work on the theory of machine learning has formalized replicability as the demand that an…

Machine Learning · Computer Science 2026-04-15 Eric Eaton , Marcel Hussing , Michael Kearns , Aaron Roth , Sikata Bela Sengupta , Jessica Sorrell

We describe an algorithm for computing the maximal invariant set for a Markov chain with linear safety constraints on the distribution over states. We then propose a Markov chain synthesis method that guarantees finite determination of the…

Optimization and Control · Mathematics 2019-05-06 Dylan Janak , Behçet Açıkmeşe

Despite the growing body of work in interpretable machine learning, it remains unclear how to evaluate different explainability methods without resorting to qualitative assessment and user-studies. While interpretability is an inherently…

Machine Learning · Computer Science 2020-07-16 An-phi Nguyen , María Rodríguez Martínez

A Markov-chain model is developed for the purpose estimation of the cure rate of non-performing loans. The technique is performed collectively, on portfolios and it can be applicable in the process of calculation of credit impairment. It is…

Risk Management · Quantitative Finance 2018-07-03 Vilislav Boutchaktchiev

Bayesian analysis for Markov jump processes is a non-trivial and challenging problem. Although exact inference is theoretically possible, it is computationally demanding thus its applicability is limited to a small class of problems. In…

Computation · Statistics 2017-02-08 Vassilios Stathopoulos , Mark A. Girolami

Bayesian analysis often concerns an evaluation of models with different dimensionality as is necessary in, for example, model selection or mixture models. To facilitate this evaluation, transdimensional Markov chain Monte Carlo (MCMC)…

Methodology · Statistics 2018-08-13 Daniel W. Heck , Antony M. Overstall , Quentin F. Gronau , Eric-Jan Wagenmakers

Important computational physics problems are often large-scale in nature, and it is highly desirable to have robust and high performing computational frameworks that can quickly address these problems. However, it is no trivial task to…

Mathematical Software · Computer Science 2017-09-18 J. Chang , K. B. Nakshatrala , M. G. Knepley , L. Johnsson

Bayesian regression remains a simple but effective tool based on Bayesian inference techniques. For large-scale applications, with complicated posterior distributions, Markov Chain Monte Carlo methods are applied. To improve the well-known…

Computation · Statistics 2020-09-28 Joris Tavernier , Jaak Simm , Adam Arany , Karl Meerbergen , Yves Moreau
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