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Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun

Purpose: Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image…

Medical Physics · Physics 2019-03-14 Juan Liu , Andrew S. Nencka , L. Tugan Muftuler , Brad Swearingen , Robin Karr , Kevin M. Koch

Quantitative susceptibility mapping (QSM) provides a valuable tool for quantifying susceptibility distributions in human brains; however, two types of opposing susceptibility sources (i.e., paramagnetic and diamagnetic), may coexist in a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Min Li , Chen Chen , Zhenghao Li , Yin Liu , Shanshan Shan , Peng Wu , Pengfei Rong , Feng Liu , G. Bruce Pike , Alan H. Wilman , Hongfu Sun , Yang Gao

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve the quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. In PDI, a deep…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Jinwei Zhang , Hang Zhang , Mert Sabuncu , Pascal Spincemaille , Thanh Nguyen , Yi Wang

Quantitative susceptibility mapping (QSM) is a valuable MRI post-processing technique that quantifies the magnetic susceptibility of body tissue from phase data. However, the traditional QSM reconstruction pipeline involves multiple…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Yang Gao , Zhuang Xiong , Amir Fazlollahi , Peter J Nestor , Viktor Vegh , Fatima Nasrallah , Craig Winter , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) is a MRI technique that estimates tissue magnetic susceptibility. The generation of QSM requires solving a challenging ill-posed field-to-source inversion problem. Recently, several deep learning…

Medical Physics · Physics 2022-06-28 Juan Liu , Kevin Koch

Abnormal iron accumulation in the brain subcortical nuclei has been reported to be correlated to various neurodegenerative diseases, which can be measured through the magnetic susceptibility from the quantitative susceptibility mapping…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Chao Chai , Pengchong Qiao , Bin Zhao , Huiying Wang , Guohua Liu , Hong Wu , E Mark Haacke , Wen Shen , Chen Cao , Xinchen Ye , Zhiyang Liu , Shuang Xia

Quantitative Susceptibility Mapping is a parametric imaging technique to estimate the magnetic susceptibilities of biological tissues from MRI phase measurements. This problem of estimating the susceptibility map is ill posed. Regularized…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Arvind Balachandrasekaran , Davood Karimi , Camilo Jaimes , Ali Gholipour

Quantitative susceptibility mapping (QSM) is a post-processing technique for deriving tissue magnetic susceptibility distribution from MRI phase measurements. Deep learning (DL) algorithms hold great potential for solving the ill-posed QSM…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Yang Gao , Zhuang Xiong , Shanshan Shan , Yin Liu , Pengfei Rong , Min Li , Alan H Wilman , G. Bruce Pike , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

This article provides recommendations for implementing quantitative susceptibility mapping (QSM) for clinical brain research. It is a consensus of the ISMRM Electro-Magnetic Tissue Properties Study Group. While QSM technical development…

We propose Nonlinear Dipole Inversion (NDI) for high-quality Quantitative Susceptibility Mapping (QSM) without regularization tuning, while matching the image quality of state-of-the-art reconstruction techniques. In addition to avoiding…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Daniel Polak , Itthi Chatnuntawech , Jaeyeon Yoon , Siddharth Srinivasan Iyer , Jongho Lee , Peter Bachert , Elfar Adalsteinsson , Kawin Setsompop , Berkin Bilgic

A learning-based posterior distribution estimation method, Probabilistic Dipole Inversion (PDI), is proposed to solve quantitative susceptibility mapping (QSM) inverse problem in MRI with uncertainty estimation. A deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Jinwei Zhang , Hang Zhang , Mert Sabuncu , Pascal Spincemaille , Thanh Nguyen , Yi Wang

Quantitative susceptibility mapping (QSM) utilizes MRI phase information to estimate tissue magnetic susceptibility. The generation of QSM requires solving ill-posed background field removal (BFR) and field-to-source inversion problems.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Juan Liu , Kevin M Koch

Recently, deep learning methods have been proposed for quantitative susceptibility mapping (QSM) data processing: background field removal, field-to-source inversion, and single-step QSM reconstruction. However, the conventional padding…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Juan Liu

Deep learning based Quantitative Susceptibility Mapping (QSM) has shown great potential in recent years, obtaining similar results to established non-learning approaches. Many current deep learning approaches are not data consistent,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Francesco Cognolato , Kieran O'Brien , Jin Jin , Simon Robinson , Frederik B. Laun , Markus Barth , Steffen Bollmann

Quantitative susceptibility mapping (QSM) aims to visualize the three dimensional susceptibility distribution by solving the field-to-source inverse problem using the phase data in magnetic resonance signal. However, the inverse problem is…

Numerical Analysis · Mathematics 2018-12-31 Chenglong Bao , Jae Kyu Choi , Bin Dong

Magnetic resonance imaging (MRI) reconstruction is an active inverse problem which can be addressed by conventional compressed sensing (CS) MRI algorithms that exploit the sparse nature of MRI in an iterative optimization-based manner.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Yuxiang Dai , Peixian Zhuang

Meta-learning has recently been an emerging data-efficient learning technique for various medical imaging operations and has helped advance contemporary deep learning models. Furthermore, meta-learning enhances the knowledge generalization…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Sriprabha Ramanarayanan , Arun Palla , Keerthi Ram , Mohanasankar Sivaprakasam

The data-driven approach of supervised learning methods has limited applicability in solving dipole inversion in Quantitative Susceptibility Mapping (QSM) with varying scan parameters across different objects. To address this generalization…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Zhuang Xiong , Yang Gao , Yin Liu , Amir Fazlollahi , Peter Nestor , Feng Liu , Hongfu Sun