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Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Mammographic breast density, a parameter used to describe the proportion of breast tissue fibrosis, is widely adopted as an evaluation characteristic of the likelihood of breast cancer incidence. In this study, we present a radiomics…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Jingxu Xu , Cheng Li , Yongjin Zhou , Lisha Mou , Hairong Zheng , Shanshan Wang

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

This study leverages graph neural networks to integrate MELC data with Radiomic-extracted features for melanoma classification, focusing on cell-wise analysis. It assesses the effectiveness of gene expression profiles and Radiomic features,…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Luis Carlos Rivera Monroy , Leonhard Rist , Martin Eberhardt , Christian Ostalecki , Andreas Bauer , Julio Vera , Katharina Breininger , Andreas Maier

Feature selection is a pattern recognition approach to choose important variables according to some criteria to distinguish or explain certain phenomena. There are many genomic and proteomic applications which rely on feature selection to…

Computer Vision and Pattern Recognition · Computer Science 2011-06-13 Fabricio Martins Lopes , David Correa Martins-Jr , Roberto M. Cesar-Jr

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

In the context of brain tumor characterization, we focused on two key questions: (a) stability of radiomics features to variability in multiregional segmentation masks obtained with fully-automatic deep segmentation methods and (b)…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Maria Nadeem , Asma Shaheen , Muhammad F. A. Chaudhary , Hassan Mohy-ud-Din

Radiomics analysis has emerged as a promising approach for extracting quantitative features from medical images to aid in cancer diagnosis and treatment. However, radiomics research currently lacks standardization, and radiomics features…

Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a…

We study information theoretic methods for ranking biomarkers. In clinical trials there are two, closely related, types of biomarkers: predictive and prognostic, and disentangling them is a key challenge. Our first step is to phrase…

Machine Learning · Statistics 2016-12-06 Konstantinos Sechidis , Emily Turner , Paul D. Metcalfe , James Weatherall , Gavin Brown

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

We introduce RadiomicsFill, a synthetic tumor generator conditioned on radiomics features, enabling detailed control and individual manipulation of tumor subregions. This conditioning leverages conventional high-dimensional features of the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Inye Na , Jonghun Kim , Hyunjin Park

The application of machine learning to radiological images is an increasingly active research area that is expected to grow in the next five to ten years. Recent advances in machine learning have the potential to recognize and classify…

Image and Video Processing · Electrical Eng. & Systems 2019-04-01 Zhenwei Zhang , Ervin Sejdic

The presence of MGMT promoter methylation significantly affects how well chemotherapy works for patients with Glioblastoma Multiforme (GBM). Currently, confirmation of MGMT promoter methylation relies on invasive brain tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Rawan Alyahya , Asrar Alruwayqi , Atheer Alqarni , Asma Alkhaldi , Metab Alkubeyyer , Xin Gao , Mona Alshahrani

The de facto standard of dynamic histogram binning for radiomic feature extraction leads to an elevated sensitivity to fluctuations in annotated regions. This may impact the majority of radiomic studies published recently and contribute to…

Image and Video Processing · Electrical Eng. & Systems 2022-11-11 Darryl E. Wright , Cole Cook , Jason Klug , Panagiotis Korfiatis , Timothy L. Kline

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

Quantitative Methods · Quantitative Biology 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

Medical Physics · Physics 2025-10-22 Haotian Feng , Ke Sheng