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Advances in quantum algorithms suggest a tentative scaling advantage on certain combinatorial optimization problems. Recent work, however, has also reinforced the idea that barren plateaus render variational algorithms ineffective on large…

Quantum Physics · Physics 2025-03-14 Tim Bode , Krish Ramesh , Tobias Stollenwerk

Hybrid Quantum Neural Networks (HQNNs) have gained attention for their potential to enhance computational performance by incorporating quantum layers into classical neural network (NN) architectures. However, a key question remains: Do…

Quantum Physics · Physics 2025-02-24 Muhammad Kashif , Alberto Marchisio , Muhammad Shafique

Despite numerous advances in the field and a seemingly ever-increasing amount of investment, we are still some years away from seeing a production quantum computer in action. However, it is possible to make some educated guesses about the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-22 James H. Davenport , Jessica R. Jones , Matthew Thomason

The observation of an unequivocal quantum speedup remains an elusive objective for quantum computing. The D-Wave quantum annealing processors have been at the forefront of experimental attempts to address this goal, given their relatively…

Quantum Physics · Physics 2018-08-08 Tameem Albash , Daniel A. Lidar

Quantum Annealing, or Quantum Stochastic Optimization, is a classical randomized algorithm which provides good heuristics for the solution of hard optimization problems. The algorithm, suggested by the behaviour of quantum systems, is an…

Quantum Physics · Physics 2011-07-06 Diego de Falco , Dario Tamascelli

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

Protein folding is a central challenge in computational biology, with important applications in molecular biology, drug discovery and catalyst design. As a hard combinatorial optimisation problem, it has been studied as a potential target…

Quantum annealing is a computing paradigm that has the ambitious goal of efficiently solving large-scale combinatorial optimization problems of practical importance. However, many challenges have yet to be overcome before this goal can be…

Solving problems related to planning and operations of large-scale power systems is challenging on classical computers due to their inherent nature as mixed-integer and nonlinear problems. Quantum computing provides new avenues to approach…

Quantum Physics · Physics 2025-05-02 Willie Aboumrad , Phani R V Marthi , Suman Debnath , Martin Roetteler , Evgeny Epifanovsky

We study the glued-trees problem of Childs et. al. in the adiabatic model of quantum computing and provide an annealing schedule to solve an oracular problem exponentially faster than classically possible. The Hamiltonians involved in the…

Quantum Physics · Physics 2013-05-30 Daniel Nagaj , Rolando D. Somma , Maria Kieferova

Quantum annealing (QA) is a method for solving combinatorial optimization problems. We can estimate the computational time for QA using the adiabatic condition. The adiabatic condition consists of two parts: an energy gap and a transition…

Quantum Physics · Physics 2024-08-28 Hiroshi Hayasaka , Takashi Imoto , Yuichiro Matsuzaki , Shiro Kawabata

Computing nonlinear functions over multilinear forms is a general problem with applications in risk analysis. For instance in the domain of energy economics, accurate and timely risk management demands for efficient simulation of millions…

Realizing quantum speedup for practically relevant, computationally hard problems is a central challenge in quantum information science. Using Rydberg atom arrays with up to 289 qubits in two spatial dimensions, we experimentally…

Quantum computing will change the way we tackle certain problems. It promises to dramatically speed-up many chemical, financial, and machine-learning applications. However, to capitalize on those promises, complex design flows composed of…

Quantum Physics · Physics 2020-10-28 Lukas Burgholzer , Robert Wille

Quantum annealing is an innovative idea and method for avoiding the increase of the calculation cost of the combinatorial optimization problem. Since the combinatorial optimization problems are ubiquitous, quantum annealing machine with…

Statistical Mechanics · Physics 2020-01-13 Shohei Watabe , Yuya Seki , Shiro Kawabata

Quantum annealing promises to be an effective heuristic for complex NP-hard problems. However, clear demonstrations of quantum advantage are wanting, primarily constrained by the difficulty of embedding the problem into the quantum…

Quantum Physics · Physics 2022-11-15 Minjae Jo , Michael Hanks , M. S. Kim

Quantum annealing is a heuristic optimization algorithm that exploits quantum evolution to approximately find lowest energy states. Quantum annealers have scaled up in recent years to tackle increasingly larger and more highly connected…

Quantum Physics · Physics 2025-07-04 Humberto Munoz Bauza , Daniel A. Lidar

Quantum machine learning algorithms could provide significant speed-ups over their classical counterparts; however, whether they could also achieve good generalization remains unclear. Recently, two quantum perceptron models which give a…

Quantum Physics · Physics 2022-06-22 Mathieu Roget , Giuseppe Di Molfetta , Hachem Kadri

Quantum error-correcting codes (QECCs) is at the heart of fault-tolerant quantum computing. As the size of quantum platforms is expected to grow, one of the open questions is to design new optimal codes of ever-increasing size. A related…

Quantum Physics · Physics 2024-07-08 Refat Ismail , Ashish Kakkar , Anatoly Dymarsky

One of the most well-known problems in transportation and logistics is the Capacitated Vehicle Routing Problem (CVRP). It involves optimizing a set of truck routes to service a set of customers, subject to limits on truck capacity, to…

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