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As machine learning continues to gain momentum in the neuroscience community, we witness the emergence of novel applications such as diagnostics, characterization, and treatment outcome prediction for psychiatric and neurological disorders,…

Computer Vision and Pattern Recognition · Computer Science 2018-04-27 Maxim Sharaev , Alexander Andreev , Alexey Artemov , Alexander Bernstein , Evgeny Burnaev , Ekaterina Kondratyeva , Svetlana Sushchinskaya , Renat Akzhigitov

We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

Machine Learning · Statistics 2016-10-04 Xin Gao , Raymond J. Carroll

We extend recent work (Brehmer, et. al., 2018) that use neural networks as surrogate models for likelihood-free inference. As in the previous work, we exploit the fact that the joint likelihood ratio and joint score, conditioned on both…

Machine Learning · Statistics 2018-08-06 Markus Stoye , Johann Brehmer , Gilles Louppe , Juan Pavez , Kyle Cranmer

Although there is growing interest in measuring integrated information in computational and cognitive systems, current methods for doing so in practice are computationally unfeasible. Existing and novel integration measures are investigated…

Neurons and Cognition · Quantitative Biology 2017-02-08 Max Tegmark

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

Given the joint chances of a pair of random variables one can compute quantities of interest, like the mutual information. The Bayesian treatment of unknown chances involves computing, from a second order prior distribution and the data…

Machine Learning · Computer Science 2007-05-23 Marcus Hutter , Marco Zaffalon

The assumption that data samples are independent and identically distributed (iid) is standard in many areas of statistics and machine learning. Nevertheless, in some settings, such as social networks, infectious disease modeling, and…

Methodology · Statistics 2019-02-06 Eli Sherman , Ilya Shpitser

Malaria can be diagnosed by the presence of parasites and symptoms (usually fever) due to the parasites. In endemic areas, however, an individual may have fever attributable either to malaria or to other causes. Thus, the parasite level of…

Methodology · Statistics 2025-07-22 Zhaoyang Tian , Kun Liang , Pengfei Li

To improve the precision of inferences and reduce costs there is considerable interest in combining data from several sources such as sample surveys and administrative data. Appropriate methodology is required to ensure satisfactory…

Methodology · Statistics 2022-10-21 Dexter Cahoy , Joseph Sedransk

Parametric inference posits a statistical model that is a specified family of probability distributions. Restricted inference, e.g., restricted likelihood ratio testing, attempts to exploit the structure of a statistical submodel that is a…

Statistics Theory · Mathematics 2019-03-22 Michael W. Trosset , Carey E. Priebe

Cognitive diagnosis models have been popularly used in fields such as education, psychology, and social sciences. While parametric likelihood estimation is a prevailing method for fitting cognitive diagnosis models, nonparametric…

Statistics Theory · Mathematics 2025-10-01 Chengyu Cui , Yanlong Liu , Gongjun Xu

This study applied Bayesian optimization likelihood-free inference(BOLFI) to virus dynamics experimental data and efficiently inferred the model parameters with uncertainty measure. The computational benefit is remarkable compared to…

Applications · Statistics 2025-09-11 Yingying Xu

Overall, the two main contributions of this work include the application of sentence simplification to association extraction as described above, and the use of distributional semantics for concept extraction. The proposed work on concept…

Computation and Language · Computer Science 2011-09-13 Siddhartha Jonnalagadda

For the purpose of causal inference we employ a stochastic model of the data generating process, utilizing individual propensity probabilities for the treatment, and also individual and counterfactual prognosis probabilities for the…

Methodology · Statistics 2024-07-15 Brian Knaeble , Mehdi Hakim-Hashemi , Mark A. Abramson

Cognitive architectures are influential, integrated computational frameworks for modeling cognitive processes. Due to a variety of factors, however, researchers using cognitive architectures to explain and predict human performance rarely…

Neurons and Cognition · Quantitative Biology 2024-10-24 Andrea Stocco , Konstantinos Mitsopoulos , Yuxue C. Yang , Holly S. Hake , Theodros Haile , Bridget Leonard , Kevin Gluck

Understanding epistasis (genetic interaction) may shed some light on the genomic basis of common diseases, including disorders of maximum interest due to their high socioeconomic burden, like schizophrenia. Distance correlation is an…

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

We study inference with a small labeled sample, a large unlabeled sample, and high-quality predictions from an external model. We link prediction-powered inference with empirical likelihood by stacking supervised estimating equations based…

Methodology · Statistics 2025-12-19 Guanghui Wang , Mengtao Wen , Changliang Zou

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq