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Deep learning with medical data often requires larger samples sizes than are available at single providers. While data sharing among institutions is desirable to train more accurate and sophisticated models, it can lead to severe privacy…

Machine Learning · Computer Science 2018-12-05 Brett K. Beaulieu-Jones , William Yuan , Samuel G. Finlayson , Zhiwei Steven Wu

Hierarchical Bayesian methods enable information sharing across multiple related regression problems. While standard practice is to model regression parameters (effects) as (1) exchangeable across datasets and (2) correlated to differing…

Methodology · Statistics 2021-07-15 Brian L. Trippe , Hilary K. Finucane , Tamara Broderick

Organizations are collecting vast amounts of data, but they often lack the capabilities needed to fully extract insights. As a result, they increasingly share data with external experts, such as analysts or researchers, to gain value from…

Machine Learning · Computer Science 2025-05-16 Yusi Wei , Hande Y. Benson , Joseph K. Agor , Muge Capan

Randomized response is attractive for privacy preserving data collection because the provided privacy can be quantified by means such as differential privacy. However, recovering and analyzing statistics involving multiple dependent…

Cryptography and Security · Computer Science 2018-07-16 Staal A. Vinterbo

This work studies formal utility and privacy guarantees for a simple multiplicative database transformation, where the data are compressed by a random linear or affine transformation, reducing the number of data records substantially, while…

Machine Learning · Statistics 2009-01-13 Shuheng Zhou , Katrina Ligett , Larry Wasserman

Datasets may contain observations with multiple labels. If the labels are not mutually exclusive, and if the labels vary greatly in frequency, obtaining a sample that includes sufficient observations with scarcer labels to make inferences…

Machine Learning · Computer Science 2026-05-27 Simon Chung , Colby J. Vorland , Donna L. Maney , Andrew W. Brown

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

In survival analysis, regression models are used to understand the effects of explanatory variables (e.g., age, sex, weight, etc.) to the survival probability. However, for sensitive survival data such as medical data, there are serious…

Machine Learning · Computer Science 2017-08-28 Thông T. Nguyên , Siu Cheung Hui

There are now several large scale deployments of differential privacy used to collect statistical information about users. However, these deployments periodically recollect the data and recompute the statistics using algorithms designed for…

Machine Learning · Computer Science 2018-11-21 Matthew Joseph , Aaron Roth , Jonathan Ullman , Bo Waggoner

This article deals with the analysis of high dimensional data that come from multiple sources (experiments) and thus have different possibly correlated responses, but share the same set of predictors. The measurements of the predictors may…

Methodology · Statistics 2020-07-01 Guorong Dai , Ursula U. Müller , Raymond J. Carroll

Graphs and networks are common ways of depicting biological information. In biology, many different biological processes are represented by graphs, such as regulatory networks, metabolic pathways and protein--protein interaction networks.…

Applications · Statistics 2010-11-16 Caiyan Li , Hongzhe Li

We study two-sample variable selection: identifying variables that discriminate between the distributions of two sets of data vectors. Such variables help scientists understand the mechanisms behind dataset discrepancies. Although…

Machine Learning · Statistics 2025-11-06 Kensuke Mitsuzawa , Motonobu Kanagawa , Stefano Bortoli , Margherita Grossi , Paolo Papotti

Longitudinal electronic health record (EHR) data offer opportunities to study biomarker trajectories; however, association estimates-the primary inferential target-from standard models designed for regular observation times may be biased by…

Methodology · Statistics 2026-02-18 Cheng-Han Yang , Xu Shi , Bhramar Mukherjee

With the development of big data and machine learning, privacy concerns have become increasingly critical, especially when handling heterogeneous datasets containing sensitive personal information. Differential privacy provides a rigorous…

Machine Learning · Statistics 2025-08-08 Ziliang Shen , Caixing Wang , Shaoli Wang , Yibo Yan

The paper considers variable selection in linear regression models where the number of covariates is possibly much larger than the number of observations. High dimensionality of the data brings in many complications, such as (possibly…

Methodology · Statistics 2016-11-29 Haeran Cho , Piotr Fryzlewicz

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Federated data analytics is a framework for distributed data analysis where a server compiles noisy responses from a group of distributed low-bandwidth user devices to estimate aggregate statistics. Two major challenges in this framework…

Machine Learning · Computer Science 2022-06-10 Kamalika Chaudhuri , Chuan Guo , Mike Rabbat

We develop scalable randomized kernel methods for jointly associating data from multiple sources and simultaneously predicting an outcome or classifying a unit into one of two or more classes. The proposed methods model nonlinear…

Methodology · Statistics 2023-04-11 Sandra E. Safo , Han Lu

Motivated by challenges in the analysis of biomedical data and observational studies, we develop statistical boosting for the general class of bivariate distributional copula regression with arbitrary marginal distributions, which is suited…

Methodology · Statistics 2024-03-05 Guillermo Briseño Sanchez , Nadja Klein , Hannah Klinkhammer , Andreas Mayr

With the increasing amount of data in society, privacy concerns in data sharing have become widely recognized. Particularly, protecting personal attribute information is essential for a wide range of aims from crowdsourcing to realizing…

Cryptography and Security · Computer Science 2024-02-13 Akito Yamamoto , Tetsuo Shibuya
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