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With substantial public concerns on potential cancer risks and health hazards caused by the accumulated radiation exposure in medical imaging, reducing radiation dose in X-ray based medical imaging such as Computed Tomography Perfusion…

Image and Video Processing · Electrical Eng. & Systems 2019-10-21 Peng Liu , Ruogu Fang

Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

Neurons and Cognition · Quantitative Biology 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

Like in many other research fields, recent developments in computational imaging have focused on developing machine learning (ML) approaches to tackle its main challenges. To improve the performance of computational imaging algorithms,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Maximilian B. Kiss , Ander Biguri , Carola-Bibiane Schönlieb , K. Joost Batenburg , Felix Lucka

The accurate segmentation of Coronary Computed Tomography Angiography (CCTA) images holds substantial clinical value for the early detection and treatment of Coronary Heart Disease (CHD). The Transformer, utilizing a self-attention…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Chenchu Xu , Meng Li , Xue Wu

Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Yifan Wu , Rohit Jena , Mehmet Gulsun , Vivek Singh , Puneet Sharma , James C. Gee

X-ray computed tomography (CT) is widely utilized in the medical, industrial, and other fields to nondestructively generate three-dimensional structural images of objects. However, CT images are often affected by various artifacts, with…

Medical Physics · Physics 2025-05-27 Yang Zou , Meili Qi , Jianhua Zhang , Difei Zhang , Shuwei Wang , Jiale Zhang , Shengkun Yao , Huaidong Jiang

Deep learning based approaches have been used to improve image quality in cone-beam computed tomography (CBCT), a medical imaging technique often used in applications such as image-guided radiation therapy, implant dentistry or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Mohammadreza Amirian , Daniel Barco , Ivo Herzig , Frank-Peter Schilling

This is a preprint. The latest version has been published here: https://pubs.rsna.org/doi/10.1148/ryai.230275 Purpose: Sparse-view computed tomography (CT) is an effective way to reduce dose by lowering the total number of views acquired,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Johannes Thalhammer , Manuel Schultheiss , Tina Dorosti , Tobias Lasser , Franz Pfeiffer , Daniela Pfeiffer , Florian Schaff

Coronary heart disease (CHD) is the leading cause of adult death in the United States and worldwide, and for which the coronary angiography procedure is the primary gateway for diagnosis and clinical management decisions. The…

Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Ziheng Zhang , Zihan Li , Dandan Shan , Yuehui Qiu , Qingqi Hong , Qingqiang Wu

Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Satu I. Inkinen , Mikael A. K. Brix , Miika T. Nieminen , Simon Arridge , Andreas Hauptmann

Deep learning algorithms offer a powerful means to automatically analyze the content of medical images. However, many biological samples of interest are primarily transparent to visible light and contain features that are difficult to…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Roarke Horstmeyer , Richard Y. Chen , Barbara Kappes , Benjamin Judkewitz

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

BACKGROUND Careful evaluation of the risk of stent under-expansions before the intervention will aid treatment planning, including the application of a pre-stent plaque modification strategy. OBJECTIVES It remains challenging to achieve a…

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

Acute Coronary Syndrome (ACS) is a syndrome caused by a decrease in blood flow in the coronary arteries. The ACS is usually related to coronary thrombosis and is primarily caused by plaque rupture followed by plaque erosion and calcified…

Computer Vision and Pattern Recognition · Computer Science 2020-05-22 Tae Joon Jun , Soo-Jin Kang , June-Goo Lee , Jihoon Kweon , Wonjun Na , Daeyoun Kang , Dohyeun Kim , Daeyoung Kim , Young-Hak Kim

Calcium imaging is an essential tool to study the activity of neuronal populations. However, the high level of background fluorescence in images hinders the accurate identification of neurons and the extraction of neuronal activities. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Seungjae Han , Eun-Seo Cho , Inkyu Park , Kijung Shin , Young-Gyu Yoon

Coronary artery disease (CAD) remains a prevalent cardiovascular condition, posing significant health risks worldwide. This pathology, characterized by plaque accumulation in coronary artery walls, leads to myocardial ischemia and various…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Xinyun Liu , Chen Zhao

Non-contrast computed tomography calcium scoring (CTCS) is widely recognized as an effective tool for cardiovascular risk stratification. This study aimed to develop a novel machine learning framework for predicting myocardial ischemia from…

Machine Learning · Computer Science 2026-05-22 Juhwan Lee , Sadeer Al-Kindi , Ammar Hoori , Tao Hu , Hao Wu , Justin N. Kim , Robert Gilkeson , Sanjay Rajagopalan , David L. Wilson
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