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Our work was motivated by a recent study on birth defects of infants born to pregnant women exposed to a certain medication for treating chronic diseases. Outcomes such as birth defects are rare events in the general population, which often…

Applications · Statistics 2017-02-24 Ronghui Xu , Jue Hou , Christina D. Chambers

High-dimensional spectral data -- routinely generated in dairy production -- are used to predict a range of traits in milk products. Partial least squares (PLS) regression is ubiquitously used for these prediction tasks. However, PLS…

Determining the precise rank is an important problem in many large-scale applications with matrix data exploiting low-rank plus noise models. In this paper, we suggest a universal approach to rank inference via residual subsampling (RIRS)…

Statistics Theory · Mathematics 2024-11-12 Xiao Han , Qing Yang , Yingying Fan

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

Methodology · Statistics 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

The purpose of this work is to improve the efficiency in estimating the average causal effect (ACE) on the survival scale where right-censoring exists and high-dimensional covariate information is available. We propose new estimators using…

Methodology · Statistics 2021-06-29 Ran Dai , Cheng Zheng , Mei-Jie Zhang

Learning models have been shown to rely on spurious correlations between non-predictive features and the associated labels in the training data, with negative implications on robustness, bias and fairness. In this work, we provide a…

Machine Learning · Statistics 2025-05-29 Simone Bombari , Marco Mondelli

DNA copy number and mRNA expression are widely used data types in cancer studies, which combined provide more insight than separately. Whereas in existing literature the form of the relationship between these two types of markers is fixed a…

In this work, we show that Spearman's correlation coefficient test about $H_0:\rho_s=0$ found in most statistical software packages is theoretically incorrect and performs poorly when bivariate normality assumptions are not met or the…

Methodology · Statistics 2020-08-05 Han Yu , Alan D. Hutson

It is emphasised that for epidemiological studies where disease incidence is rare, results from conventional proportional hazards models can often correctly estimate causal associations. The well-known "backdoor criteria" from…

Methodology · Statistics 2021-10-06 A. J. Webster

Conditional independence (CI) testing arises naturally in many scientific problems and applications domains. The goal of this problem is to investigate the conditional independence between a response variable $Y$ and another variable $X$,…

Methodology · Statistics 2025-10-07 Adel Javanmard , Mohammad Mehrabi

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for spurious correlation induced from the shared history, the task also requires sufficient…

We address the problem of survival regression modelling with multivariate responses and nonlinear covariate effects. Our model extends the proportional hazards model by introducing several weakly-parametric elements: the marginal baseline…

Methodology · Statistics 2025-10-16 Na Lei , Mark A. Wolters , Wenqing He

We develop new tools for formal inference and informal model validation in the analysis of spatial point pattern data. The score test is generalized to a "pseudo-score" test derived from Besag's pseudo-likelihood, and to a class of…

Methodology · Statistics 2012-05-18 Adrian Baddeley , Ege Rubak , Jesper Møller

Instrumental variables (IV) are a useful tool for estimating causal effects in the presence of unmeasured confounding. IV methods are well developed for uncensored outcomes, particularly for structural linear equation models, where simple…

Methodology · Statistics 2019-02-01 Behzad Kianian , Jung In Kim , Jason P. Fine , Limin Peng

Respondent-driven sampling (RDS) is a popular method for sampling hard-to-survey populations that leverages social network connections through peer recruitment. While RDS is most frequently applied to estimate the prevalence of infections…

Methodology · Statistics 2016-10-24 Ashton M. Verdery , Jacob C. Fisher , Nalyn Siripong , Kahina Abdesselam , Shawn Bauldry

Matching is a popular nonparametric covariate adjustment strategy in empirical health services research. Matching helps construct two groups comparable in many baseline covariates but different in some key aspects under investigation. In…

Applications · Statistics 2023-08-17 Chang Chen , Zhiyu Qian , Bo Zhang

Synthetic high-resolution (HR) \& low-resolution (LR) pairs are widely used in existing super-resolution (SR) methods. To avoid the domain gap between synthetic and test images, most previous methods try to adaptively learn the synthesizing…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Zhengxiong Luo , Yan Huang , Shang Li , Liang Wang , Tieniu Tan

Over the last two decades, many exciting variable selection methods have been developed for finding a small group of covariates that are associated with the response from a large pool. Can the discoveries from these data mining approaches…

Statistics Theory · Mathematics 2017-07-24 Jianqing Fan , Qi-Man Shao , Wen-Xin Zhou

Residual variance and the signal-to-noise ratio are important quantities in many statistical models and model fitting procedures. They play an important role in regression diagnostics, in determining the performance limits in estimation and…

Methodology · Statistics 2012-09-04 Lee H. Dicker

Focusing on Stable Roommates (SR) instances, we contribute to the toolbox for conducting experiments for stable matching problems. We introduce a polynomial-time computable pseudometric to measure the similarity of SR instances, analyze its…

Computer Science and Game Theory · Computer Science 2022-08-09 Niclas Boehmer , Klaus Heeger , Stanisław Szufa
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