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Synthetic biology is the engineering of cellular networks. It combines principles of engineering and the knowledge of biological networks to program the behavior of cells. Computational modeling techniques in conjunction with molecular…

Quantitative Methods · Quantitative Biology 2009-02-17 Deepak Chandran , Frank T. Bergmann , Herbert M. Sauro

We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a…

Other Computer Science · Computer Science 2009-11-16 Russ Harmer

In this paper, we introduce a variational Bayesian algorithm (VBA) for image blind deconvolution. Our generic framework incorporates smoothness priors on the unknown blur/image and possible affine constraints (e.g., sum to one) on the blur…

Computer Vision and Pattern Recognition · Computer Science 2021-10-15 Yunshi Huang , Emilie Chouzenoux , Jean-Christophe Pesquet

There is a concerted effort to build domain-general artificial intelligence in the form of universal neural network models with sufficient computational flexibility to solve a wide variety of cognitive tasks but without requiring…

Neural and Evolutionary Computing · Computer Science 2023-03-27 Jascha Achterberg , Danyal Akarca , Moataz Assem , Moritz Heimbach , Duncan E. Astle , John Duncan

This paper studies the mathematical properties of collectively canalizing Boolean functions, a class of functions that has arisen from applications in systems biology. Boolean networks are an increasingly popular modeling framework for…

Discrete Mathematics · Computer Science 2023-06-07 Claus Kadelka , Benjamin Keilty , Reinhard Laubenbacher

The generating functional method is employed to investigate the synchronous dynamics of Boolean networks, providing an exact result for the system dynamics via a set of macroscopic order parameters. The topology of the networks studied and…

Disordered Systems and Neural Networks · Physics 2015-05-28 Alexander Mozeika , David Saad

The world is fundamentally compositional, so it is natural to think of visual recognition as the recognition of basic visually primitives that are composed according to well-defined rules. This strategy allows us to recognize unseen complex…

Computer Vision and Pattern Recognition · Computer Science 2018-01-29 Rodrigo Santa Cruz , Basura Fernando , Anoop Cherian , Stephen Gould

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular nodes, each being associated to a Boolean variable and a…

Discrete Mathematics · Computer Science 2025-06-24 José E. R. Cury , Patrícia Tenera Roxo , Vasco Manquinho , Claudine Chaouiya , Pedro T. Monteiro

Boolean networks, first developed in the late 1960s as a tool for studying complex disordered dynamical systems, consist of nodes governed by Boolean functions whose evolution is entirely deterministic in that the state of the network at a…

Quantum Physics · Physics 2023-03-02 Ian T. Durham

Amplitude demodulation is a classical operation used in signal processing. For a long time, its effective applications in practice have been limited to narrowband signals. In this work, we generalize amplitude demodulation to wideband…

Signal Processing · Electrical Eng. & Systems 2021-06-16 Mantas Gabrielaitis

We describe a question answering model that applies to both images and structured knowledge bases. The model uses natural language strings to automatically assemble neural networks from a collection of composable modules. Parameters for…

Computation and Language · Computer Science 2016-06-09 Jacob Andreas , Marcus Rohrbach , Trevor Darrell , Dan Klein

"Module networks" are a framework to learn gene regulatory networks from expression data using a probabilistic model in which coregulated genes share the same parameters and conditional distributions. We present a method to infer ensembles…

Quantitative Methods · Quantitative Biology 2009-04-09 Tom Michoel , Riet De Smet , Anagha Joshi , Kathleen Marchal , Yves Van de Peer

Bayesian networks (BNs) are a widely used class of probabilistic graphical models employed in numerous application domains. However, inferring the network's graphical structure from data remains challenging. Bayesian structure learners…

Machine Learning · Computer Science 2025-11-19 William Zhao , Guy Van den Broeck , Benjie Wang

In this paper we propose a new approach to quantum neural networks. Our multi-layer architecture avoids the use of measurements that usually emulate the non-linear activation functions which are characteristic of the classical neural…

Quantum Physics · Physics 2020-11-30 Viet Pham Ngoc , Herbert Wiklicky

We propose a model to show the self-assembling of network-like structures between a set of nodes without using preexisting positional information or long-range attraction of the nodes. The model is based on Brownian agents that are capable…

Statistical Mechanics · Physics 2009-11-07 Frank Schweitzer , Benno Tilch

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

In this paper, we focus on the study of quotients of Boolean control networks (BCNs) with the motivation that they might serve as smaller models that still carry enough information about the original network. Given a BCN and an equivalence…

Optimization and Control · Mathematics 2020-07-13 Rui Li , Qi Zhang , Tianguang Chu

The colloid cellular automata do not imitate the physical structure of colloids but are governed by logical functions derived from the colloids. We analyse the space-time complexity of Boolean circuits derived from the electrical responses…

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

Neurons and Cognition · Quantitative Biology 2026-02-24 Alessandro Salatiello